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Transcript
CHONPS Creature Creation Activity Class Set-No Writing Please! A mad scientist has been at work here in Parker, Colorado. He has created a special strand of DNA. He wants to insert this strand into a fetal cell culture where the DNA, with the help of various enzymes, will then be transcribed and translated into specific proteins. His hope is that the fetal cell will divide and divide, and a creature will eventually be “born” with those specific traits coded for by the proteins that were made. He plans to name his creature CHONPS. Why is this significant? A young scientist gets a copy of this CHONPS DNA code on paper. It is your task to transcribe and translate the DNA. Then use the attached charts to figure out what this CHONPS will actually look like. You then will create your creature on cardstock by drawing, coloring, and clearly illustrating his or her traits. You must embellish your creation as it must not just be a 2-D drawing. You must also include some sort of “scene” for your creature like a day at the beach or at the prom. A 3-D model would be great as well and does not require a “scene”. You will be transcribing and translating the left side of DNA only! Use the following chart to find out which amino acids the mRNAs is coding for. Then determine the complementary tRNA that will bring that amino acid to the ribosome in order to assemble the protein. You must complete the tRNA anticodon strand as well in order to receive credit for this portion of the assignment. If the MRNA codon is… UUU, UUC UUA, UUG, CUU, CUC, CUA, CUG AUU, AUC, AUA AUG GUU, GUC, GUA, GUG UGU, UGC UGG CGU, CGC, CGA, CGG, AGA, AGG GGU, GGC, GGA, GGG AGU, AGC, UCU, UCC, UCA, UCG CCU, CCC, CCA, CCG ACU, ACC, ACA, ACG GCU, GCC, GCA, GCG UAU, UAC CAU, CAC CAA, CAG AAU, AAC AAA, AAG GAU, GAC GAA, GAG UAA, UAG, UGA Then the amino acid it codes for will be… Phenylalanine Leucine Isoleucine Methionine-start; proteins always begin with this Valine Cysteine Tryptophan Arginine Glycine Serine Proline Threonine Alanine Tyrosine Histidine Glutamine Asparagine Lysine Aspartic Acid Glutamic Acid STOP Note: Methionine is an amino acid that codes for START. It is the signal that a new protein is about to be built. Every protein you make will begin with methionine. There are three codons for STOP: UAA, UAG, and UGA. They are signals to the ribosome that the protein is finished being built and it will detach from the ribosome. Use the following chart to determine what traits are being coded for by the proteins that the CHONPS DNA specified. If you have transcribed and translated correctly, you will have seven traits for your creature. If the Amino Acid Sequence is… Glycine-serine-threonine Cysteine-tryptophan-arginine Isoleucine-aspartic acid-glutamic acid Phenylalanine-isoleucine-valine Phenylalanine-isoleucine-cysteine Phenylalanine-isoleucine-alanine-tyrosine Alanine-tyrosine-histidine Isoleucine-cysteine-tryptophan Isoleucine-tyrosine-histidine-glycine-leucine Phenylalanine-isoleucine-tyrosine-serine Phenylalanine-isoleucine-tryptophan Isoleucine-tryptophan-arginine Isoleucine-arginine-glycine Isoleucine-glycine-serine Phenylalanine-isoleucine-histidine-arginine Phenylalanine-isoleucine-glutamine-threonine Phenylalanine-isoleucine-arginine Isoleucine-serine-proline Isoleucine-threonine-alanine Isoleucine-alanine-tyrosine Isoleucine-histidine-glutamine-serine-tryptophan Phenylalanine-isoleucine-glycine Phenylalanine-isoleucine-serine Phenylalanine-isoleucine-proline Phenylalanine-isoleucine-threonine Isoleucine-glutamine-asparagine-lysine Phenylalanine-isoleucine-asparagine-glycine Phenylalanine-isoleucine-lysine-cysteine Isoleucine-Asparagine-lysine Isoleucine-lysine-aspartic acid Phenylalanine-isoleucine-aspartic acid-tryptophan Phenylalanine-isoleucine-glutamic acid-serine Then the Trait being coded for is… Two eyes One eye Three eyes Hairless Straight hair Freckles Short nose Long nose Female Striped skin Curly hair Plump Skinny Two legs Polka-dotted skin Yellow skin Hairy One leg Three legs Six legs Male Red hair Black hair Brown hair Orange hair Needs glasses Blue skin Green skin Big ears Big mouth Orange skin Red skin Make sure to mark the traits that you have determined your creature to have on your code sheet.