* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Cell Membrane
Survey
Document related concepts
Cell culture wikipedia , lookup
Artificial cell wikipedia , lookup
Cellular differentiation wikipedia , lookup
Human genetic resistance to malaria wikipedia , lookup
Sexual reproduction wikipedia , lookup
Introduction to genetics wikipedia , lookup
Symbiogenesis wikipedia , lookup
Evolution of metal ions in biological systems wikipedia , lookup
Cell growth wikipedia , lookup
Cell-penetrating peptide wikipedia , lookup
State switching wikipedia , lookup
Biochemistry wikipedia , lookup
Organ-on-a-chip wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Cell theory wikipedia , lookup
Transcript
STAAR/EOC Academy Types of Cells Eukaryotic-You and Me - Animals and Plant Prokaryotic-Bacteria- PRO means NOOOO Nucleus -Eubacteria and Archaebacteria Cell Organelles A. Cell Wall-Protection and Support-In plant cells and Bacteria as well. B. Nucleus-Control Center of Cell-The Brain C. Ribosomes-Makes Protein-Translations occurs here-Found on Rough ER-Small Dots D. Endoplasmic Reticulum-Smooth and Rough-Assembles Proteins-Rough has Ribosomes -Looks like a maze -Located near Nucleus E. Mitochondria-Power Plant of the Cell- Cellular Respiration occurs here- Makes ATP. -C6 H12 O6 + O2 CO2 + H20 + ATP- Looks like a Snake F. Lysosome-Digestion occurs here-Stomach of the Cell G. Centriole-Cell Division- Small dots located near Nucleus-Spindle fibers attach here. H. Chloroplast-Found in Plants ONLY. Photosynthesis occurs here-Looks like Poker Chips -CO2 +H2O O2 + H2O + C6 H12 O6 I. Cell Membrane-Protection and Support-Phospholipid Bilayer-Made of Phospholipids, Fatty acid tails and Protein Channels-Selectively Permeable- Allows things in and out of the cell J. Nucleolus-Small dark dot in the center of the Nucleus-Makes Ribosomes K. Chromosomes-Make DNA-Found in the Nucleus-Blue Print of life. L. Golgi Body/Golgi Apparatus-Packages proteins-Looks like pancakes-UPS/FedEx M. Vacuole-Water and mineral storage-Large in plants. N. Cytoplasm-Liquid portion of the cell-Water in the pool. O. Flagella-long whip-like structure found on some cells. Used for locomotion/movement - Sperm P. Cilia-hair-like structures found on some cells-Used for locomotion/movement Q. Nuclear Membrane/Envelope-Membrane around the nucleus-Allows things in and out. Homeostasis-Process by which organisms maintain a relatively stable internal environment. Constant internal condition. Regulates what is in and out of the cell. Cell membrane-Also called Plasma Membrane or Phospholipid Bilayer. Regulates what enters and leaves the cell. Also protects and supports it. Made of phospholipids. Phospholipid Cell Membrane Membrane Functions Diffusion-Where particles pass through a membrane fro a high to low concentration gradient. No energy required. Osmosis-A type of diffusion that is only associated with WATER. High to low concentration gradient. No energy required A. Isotonic-Water particles are balanced on the inside of the cell as well as the outside. B. Hypertonic-There is more water in the cell that outside of the cell so the cell shrinks. EX. 90% in the cell and 10% outside. Remember water in the body will balance out. C. Hypotonic-There is more water on the outside of the cell than inside. So the cell will swell and possibly burst. Hypo sounds like HIPPO. Hippos are FAT!!!!! EX. 10% water in cell and 90% water outside. Remember that water will balance out. Facilitated Diffusion-Type of diffusion where large molecule cannot diffuse across the phospholipids. Molecules have to pass through the protein channels. High to low concentration. DOES NOT REQUIRE ENERGY!!!!!! Active Transport-DIFFERENT than the other types of diffusion. LOW to HIGH CONCENTRATION. This process requires the cell to transport material in the opposite direction. Usually requires the protein channels. PROCESS REQUIRES ENERGY!!!!! Very important to know this!!!! Diffusion/Osmosis Facilitated Diffusion Active Transport Other information about cells Pinocytosis- Process by which a cell takes in liquid from the surrounding environment- CELL DRINKING Phagocytosis- Process by which extensions of cytoplasm surround and engulf large particles and take them into the cell. CELL EATING Endocytosis- Process by which a cell takes material into the cell by folding of the cell membrane. Exocytosis- Process by which a cell releases large amounts of material. EXO sounds like exit. Go to the bathroom! Adenosine Triphosphate (ATP) - one of the principal chemical compounds that living things use to store and release energy. Made in the MITOCHONDRIA by CELLULAR RESPIRATION. ENERGY!!!!!!! Adenosine Diphosphate (ADP)-reduced when an ATP molecule looses one of its phosphate molecules Photosynthesis (Plants or Autotrophs) and Cellular Respiration (Animals or Heterotrophs) STAAR/EOC-Cells, Organelles, and Functions Animal Cell Plant Cell Specialized Cells Many organisms are multi-cellular - they are made up of lots of cells, not just one! Many of these cells are specialized, sharing out the life processes (they work together as a team, supporting the organism). Specialist cells occur in both animals and plants… Animal/ Plant Cell Picture Function Specialization To carry oxygen Large surface area for oxygen Hemoglobin which binds the oxygen No nucleus To carry nerve impulses to different parts of the body Long Connections at each end Can carry electrical signals To store fat when there is excess To absorb water and minerals Large surface area which helps it to absorb water and minerals Thin cell wall makes it easy for minerals to pass through To absorb sunlight (needed for photosynthesis) Large surface area Many chloroplasts (containing chlorophyll, for photosynthesis) palisade mesophyll and spongy mesophyll. To conduct water, minerals, and nutrients through out a plant Elongated, tubular shape with thin walled sieve tubes Consists of xylem and phloem vessels Gives mechanical strength to the plant Red blood cells Nerve cell Large Round Empty looking Fat cells Root hair cells Leaf cross section Stem cells Unit 2 Biomolecules!!!! You are what you eat!!! Carbohydrates-You get these from all plant matter! Carbohydrates are made of CARBON, HYDROGEN, and OXYGEN. Monomers (BUILDING BLOCKS) are sugars. Also called monosaccharides or glucose. C6 H12 O6. Functions (THEIR JOB) is to supply the body with ENERGY!! Also in plants they are for structure and support (CELL WALL) Examples are Glucose-Blood Sugar STARCH-Complex sugar found in Potatoes, Corn, and Pasta. NOT found in MEAT!!! This is energy!!!! Cellulose-Used to make cell walls in plants, Support and Structure, Fiber for humans. We cannot digest it!!! Polysaccharides (Polymers) are long chains of monosaccharides. Like a chain. Very Complex Sugar!!! Chemical Indicators- Benedicts Solution tests for Sugar!!! Will turn sugars ORANGE!! Lugol’s or Iodine will turn STARCH black. Molecular Structure Monosaccharide Bread Polysaccharides are Complex. EX STARCH Pasta Fruit and Vegetables Potatoes=Starch ALL CARBOHYDRATES ARE FOR ENERGY!!!!!!!!!!!!!! Unit 2 Biomolecules!!!! You are what you eat!!! Lipids- You get these from Animal Fats, Oils, Nuts, and BEESWAX!!! Lipids are made of CARBON, HYDROGEN, AND OXYGEN. Monomers (BUILDING BLOCKS) are or is 1 glycerol and 3 fatty acid tails. Functions of lipids are to STORE ENERGY. Ex BODY FAT. Also MAKES up part of the cell membrane. Lipids function also as an insulator in the winter. Ex Coat or Blanket. Reduces heat loss. Examples are Body Fat-Storage Oils and Waxes!! Cooking Oil, Beeswax, Car Wax, Candle Wax!!!! Cell Membrane- Phospholipid Bilayer or Plasma Membrane. Hormones-Testosterone and Estrogen. Chemical Indicators- None. Identify lipids by placing a drop of a substance on a piece of paper. If it becomes translucent it is a lipid. Ex. French Fries from McDonalds that have been sitting in a bag for a while. Oil or Grease will make the bag somewhat see through. Saturated Fat=Solid at room temperature. Unsaturated=Liquid at room temperature. Molecular Structure Saturated and Unsaturated Fats Meat(Saturated) Glycerol and 3 Fatty Acid Tails Fish Oils(Unsaturated) Beeswax All LIPIDS ARE FOR STORAGE!!!!!!!! Unit 2 Biomolecules!!!! You are what you eat!!! Proteins- You get these from All Animal Products and Beans. Does not come from POTATOES (Starch)!!!!! Proteins are made of CARBON, HYDROGEN, OXYGEN, NITROGEN, and SULFER. Monomers (Building Blocks) are AMINO ACIDS , there are 20 different amino acids. Functions of proteins are to BUILD MUSCLE, MAKES ENZYMES, and STRUCTURE AND SUPPORT OF ALL ORGANISMS. ENZYMES SPEED UP CHEMICAL REACTIONS. Examples are Muscles- If you want big muscles eat a lot of protein and lift weights!! Hair and Cartilage- Protein Rich Shampoo and Lotion!!! Hormones- Testosterone and Estrogen. Polypeptides (Polymers) are long chains of amino acids. They are together by peptide bonds. Chemical Indicator- Biuret Solution tests for protein. Protein will turn light purple if it is present in the food source. Molecular Structure Amino Acid Farm Animals (Animal Products) Polypeptides Beans Polypeptides Tofu ALL PROTEINS ARE FOR STUCTURE AND SUPPORT (MUSCLE GROWTH). THEY ALSO MAKE ENZYMES AND HORMONES!!!! Unit 2 Biomolecules!!!! You are what you eat!!! Nucleic Acids- You do not eat these!!! DNA and RNA you get this from your parents! Monomers (Building Blocks) are Nucleotides. They are made of a PHOSPHATE, 5 CARBON SUGAR, and a NITROGEN BASE. Phosphate and the 5 carbon sugar make the backbone of DNA and RNA. Functions (THEIR JOB) are to store genetic material (DNA-Blue Print of Life) and to make proteins (RNA-Protein Synthesis). Synthesis means to create or make!!! Examples are Deoxyribonucleic Acid (DNA-Double Stranded) and Ribonucleic Acid (RNASingle Stranded) Molecular Structure Nucleotide DNA-Blueprint (instructions) Nucleotide RNA-Makes Proteins DNA IS THE BLUEPRINT OF LIFE AND RNA MAKES PROTEINS! TEKS 6C - Protein Synthesis (Transcription and Translation) Protein Synthesis DNA Contains double strand of nucleotides made of deoxyribose sugar, phosphate, and nitrogen bases (Guanine, Thymine, Adenine, Cytosine) provides instructions for the production of proteins in a process known as protein synthesis too large to leave the nucleus, so the cell needs to make RNA to send the protein making instructions to the ribosomes RNA contains single strand of nucleotides made of ribose sugar, phosphate, nitrogen bases (guanine, adenine, cytosine, Uracil) 3 types of RNA: o Messenger (mRNA)- transcribes (copies) the DNA instructions to take to the cytoplasm o Transfer (tRNA)- uses anticodons to read sections of mRNA so amino acids can attach to form a protein o Ribosomal (rRNA)- structural parts of ribosomes that help to build proteins Base Pairing Rules: DNA RNA A–T A–U C–G C–G Steps of protein synthesis: Transcription- mRNA is made from DNA template and the mRNA single strand is sent to cytoplasm to find a ribosome. This begins the protein making process. Translation- tRNA brings amino acids to the mRNA codon sections to be “read” to create the polypeptide strand http://commons.wikimedia.org/wiki/File:Mrna.gif CELLULAR RESPIRATION AND PHOTOSYNTHESIS- HANDOUT *Energy, ATP and Cellular Respiration: Energy is the ability to do work (muscle contraction). Energy can change from one form to another, but is not created or destroyed. Chemical energy stored in ATP can be converted to muscle contraction. Our bodies constantly use chemical energy for necessary cellular processes. *ALL organisms use a 2-step process to provide the energy needed for most of their biological processes: 1) Chemical energy from organic molecules like glucose is used to produce ATP in a process called cellular respiration 2) ATP provides energy for most biological processes. The process of Cellular Respiration takes place in the mitochondria!! *Cellular respiration is the process that transfers some of the chemical energy in glucose or another organic molecule to chemical energy in ATP, so energy is available in a form that is useful for biological processes. Cellular Respiration Equations = C6H12O6 + 6O2 6CO2 + 6H2O + Energy Note that not all of the energy released from glucose by cellular respiration is captured in ATP: some of the energy is converted to heat. *To use energy from food: Cellular respiration transfers energy in organic molecules such as glucose to energy in ATP. Then, ATP is used to provide energy for cellular processes. *Fermentation-produces energy from food molecules by producing ATP in the absence of oxygen. It is said to be anaerobic. The 2 main types of fermentation are alcoholic fermentation and lactic acid fermentation. Alcoholic fermentation produces carbon dioxide gas and is the reason bread dough rises. Lactic acid fermentation can cause muscle soreness due to lactic acid build-up in muscle Photosynthesis equation = 6CO2 + 6H2O 6O2 + C6H12O *Photosynthesis begins with light reactions which convert the energy in sunlight to chemical energy in ATP and NADPH. In the 2nd stage of photosynthesis, known as the Calvin Cycle, ATP and NADPH provide the energy and H needed to convert CO2 to a 3-carbon molecule which is converted to glucose. Glucose can also be used to produce starch (a storage molecule) and cellulose (a major structural molecule in plants). The process of Photosynthesis takes place in the chloroplast!! Relating Photosynthesis and Cellular respiration: Plants must also carry out cellular respiration to provide ATP for cellular processes. Notice that the equation for photosynthesis and the equation for cellular respiration are FLIPPED! The reactants become the products and the products become the reactants. Heterotrophs use the process of Cellular Respiration to obtain the energy needed stored in glucose. Autotrophs use the process of Photosynthesis to obtain their energy stored in glucose by making glucose. Darland/Spaniel (Punnett Squares) Monohybrid/Dihybrid crosses Steps for setting up a Punnett Square 1. Make a Key for trait(s) observed 2. Determine Genotypes of each parent 3. Determine possible gametes of each parent 4. Set up offspring in Punnett square 5. Analyze your results Example: A green pea plant (GG) is being crossed with a green pea plant (Gg), yellow is the recessive color. Step 1 Step 2 Key: Genotypes: G= green Parent #1 Gg ParentG#2 gametes G Step 4 Step 3 g= yellow Parent #2 GG Step 3 GG GG Gg Gg Analysis of results Step 5 G Parent #1 gametes g Genotype = 2 GG: 2 Gg ; 0 gg Phenotype = 4 Green pea plants: 0 yellow pea plants DNA Structure In 1953, James Watson and Francis Crick established the structure of DNA (Nucleic Acid). The structure is a double helix, which is like a twisted ladder. The sides of the ladder are made of alternating sugar and phosphate molecules. The sugar is deoxyribose. The rungs of the ladder are pairs of 4 types of nitrogen bases. Two of the bases are purines - adenine and guanine. The pyrimidines are thymine and cytosine. The bases are known by their coded letters A, G, T, C. These bases always bond in a certain way. Adenine will only bond to thymine. Guanine will only bond with cytosine. This is known as the Base-Pair Rule. The bases can occur in any order along a strand of DNA. The order of these bases is the code that contains the instructions. For instance ATGCACATA would code for a different gene than AATTACGGA. A strand of DNA contains millions of bases. (For simplicity, the image only contains a few.) Note that the bases attach to the sides of the ladder at the sugars and not the phosphate. The combination of a single base, a deoxyribose sugar, and a phosphate make up a nucleotide. DNA is actually a molecule or repeating nucleotides. Examine the nucleotides closer. Two of the bases are purines - adenine and guanine. The pyrimidines are thymine and cytosine. Note that the pyrimidines are single ringed and the purines are double ringed. The two sides of the DNA ladder are held together loosely by hydrogen bonds. Karyotypes: A karyotype is an organized profile of a person's chromosomes. In a karyotype, chromosomes are arranged and numbered by size, from largest to smallest. This arrangement helps scientists quickly identify chromosomal alterations that may result in a genetic disorder. To make a karyotype, scientists take a picture of someone's chromosomes, cut them out and match them up using size, banding pattern and centromere position as guides. Why It Is Done Karyotyping is done to: Determine whether the chromosomes of an adult have an abnormality that can be passed on to a child. Determine whether a chromosome defect is preventing a woman from becoming pregnant or causing miscarriages. Determine whether a chromosome defect is present in a fetus. Karyotyping also may be done to determine whether chromosomal problems may have caused a fetus to be stillborn. Determine the cause of a baby's birth defects or disability. Help determine the appropriate treatment for some types of cancer. Identify the sex of a person by determining the presence of the Y chromosome. This may be done when a newborn's sex is not clear. Karyotype Station: 1. What is a karyotype? 2. List at least 2 types of information karyotypes provide. 3. How many chromosomes do humans have? 4. Look at the karyotype below. What gender is revealed? 5. Is the karyotype “normal” or “abnormal” in the picture below? Describe how you can tell. 6. Look at the karyotype below. Is the karyotype “normal” or “abnormal” in the picture below? Describe how you can tell. 7. What is the gender of the karyotype below? TEKS 5B: Examine specialized cells, including roots, stems, and leaves of plants; and animal cells such as blood, muscle, and epithelium (ANALYZE) Blood Cells Red blood cells carry oxygen to all parts of the body. They also carry carbon dioxide back to the lungs. The blood does not have a nucleus. Blood cells do not have many mitochondria. The do not need very much energy (ATP) to carry out their function. White blood cells are also known as leukocytes. They help the body fight infection. Red blood cells Blood vessel White blood cells Plasma (blood component) platelets . Muscle Cells 1. Skeletal muscles are for movement. They are usually attached to bones. Skeletal muscles are voluntary. That means we are in control of moving them. They also use a lot of ATP or energy. 2. Smooth muscles cells are involuntary; we do not control them. Stomach cells, blood vessels, and intestinal cells contain smooth muscle. These cells also have a lot of mitochondria. 3. Cardiac cells are found only in the heart. The heart is a muscle and it never stops beating until you die or it is induced to stop. The heart functions involuntarily, meaning we do not have control over it. It also uses a lot of mitochondria. Skeletal Smooth Cardiac Characteristics Archaebacteria Prokaryotic or Eukaryotic Cells Prokaryotic Eubacteria Fungi Plantae Animalia Prokaryotic Eukaryotic Eukaryotic Eukaryotic Eukaryotic Has a Nucleus Has a Nucleus Has a Nucleus Has a Nucleus Can be both Multicellular and singlecellular Can be both Multicellular and singlecellular Multi-Cellular Multi-Cellular Autotroph(algae) Heterotroph (protozoa) Heterotroph Autotroph Heterotroph asexual / sexual asexual / sexual asexual / sexual Has a nucleus in cells? NO Nucleus NO Nucleus Single-celled or Multicellular Single-Celled Single-Celled Chemoautotroph Autotroph Chemoautotroph Heterotroph Method for Obtaining Energy Protista Type of Reproduction asexual asexual asexual / sexual Method of Movement flagella flagella cilia, flagella, pseudopods immobile Examples methanogens Amoeba, Paramecium, Euglena, algae Shelf fungus Mushrooms Puffballs Yeast E coli Cyanobacteria Streptococcus immobile Ferns, mosses, conifers, flowering plants, grasses mobile (various) Sponges, jellyfish, insects, coral, Slugs, retiles, mammals Terms to be familiar with when distinguishing between the 6 Kingdoms of Life. Prokaryote – A cell that does not contain a true nucleus. The cell contains DNA; however, the DNA is not encapsulated within a nucleus. Simple cell, less complex, does not have membrane-bound organelles. Eukaryote – A cell that contains a true nucleus. The cell contains DNA within a nucleus. Larger cell, more complex, has membrane-bound organelles. Heterotroph – used to explain an organism that consumes its energy. These organisms cannot make their own food and do not have organelles to do so. Autotroph – An organism that synthesizes its energy within the cell itself. The organism can do this by using sunlight or chemicals. Both are considered inorganic. Examples: Photoautotroph or Chemoautotroph. Plants have chloroplasts that aid in photosynthesis Cell Wall – An extra layer that surrounds the Cell Membrane. Can be composed of Cellulose (a carbohydrate found in plant cell walls) or Chitin (a carbohydrate found in Fungal Cell Walls). Eubacterial Cell Walls contain peptidoglycan, Archaebacteria contain uncommon lipids, some Protists contain pectin. Flagella – a long whip-like tail attached to a cell that is used for mobility. Cilia – many tiny little hairs that surround the cell and are also used for mobility. . Viruses A. Structure & Function o Among smallest biological particles that can cause disease in organisms o Nucleic acid core – genetic material o Protein coat (capsid) – for protection o Some have outer envelope – allows the virus to infect the host cell, tricks the cell into allowing it inside B. Comparing Viruses and Cells o Viruses are generally thought to be non-living because they do not metabolize & must have a host cell for reproduction CHARACTERISTICS VIRUS CELL DNA or RNA core, protein coat called a cell membrane, cytoplasm; eukaryotes also contain nucleus and structure capsid organelles reproduction only within a host cell independent cell division (either asexual or sexual) genetic code DNA or RNA DNA yes; in multicellular organisms, cells increase in number and growth & development no differentiate obtain and use energy no yes (metabolism) response to no yes environment change over time yes yes C. Virus Reproduction Viruses can only reproduce when inside of a host cell. 1) ATTACHMENT 2) ENTRY - genetic material injected into the cell 3) REPLICATION - viral parts are produced by the host cell’s organelles 4) ASSEMBLY - viral parts are assembled into viruses 5) RELEASE - viruses released from the host cell, sometimes bursting from the cell and destroying it Lytic cycle. Sometimes the virus is latent (non active) for a time period inside the cell and becomes active later when conditions are suitable, Lysogenic cycle. These viruses are often activated by stress. D. How Viruses Maintain and Disrupt Equilibrium o Maintaining Equilibrium (Benefits) All viruses are parasitic; however, they have constructive uses in genetic engineering. A Bacteriophage is a virus that infects bacteria and can be used to carry genes into bacteria. o Disrupting Equilibrium (Harmful) All viruses are parasitic. Major diseases: smallpox (vaccine/eradicated), flu (vaccine/epidemic), HIV, common cold, warts, encephalitis (mosquito-transmitted viral diseases), SARS, West Nile disease. E. Retroviruses have RNA instead of DNA for their genetic material The best known retrovirus is the human immunodeficiency virus (HIV). It is shown in the diagram above. The enzyme reverse transcriptase is introduced into the host cell along with the viral RNA and the enzyme synthesizes viral DNA using the RNA template. The DNA moves into the nucleus of the host cell and integrates into a chromosome. The viral DNA may be inactive for a period of years before being activated. Once it is activated, RNA is activated from the viral DNA and the host cell manufactures and assembles new HIV particles. Immune response A. pathogens: any organism that causes disease B. Cells involved in an immune response: 1. Macrophage (white blood cell) 2. Antigen Scout for the immune system; finds pathogens, consumes them and warns helper T cell of the invader Foreign proteins 3. Helper T cells General of the immune system; coordinates the attack on the pathogen 4. Killer T cells Destroys pathogen and sick infected body cells 5. Plasma B cells Produce antibodies antibodies Chemicals that attach to foreign proteins or pathogens to mark them for destruction Remember and recognize pathogens so that a second response to infection happens more rapidly Shut down the immune response 6. Memory B cells 7. Suppressor T cells HOMEOSTASIS UNIT CONTENT GUIDE Sens rs nso ors Se I. Homeostasis Environment is HOT Environment is COLD A. Definitions: o Homeostasis: process by which organisms keep internal conditions relatively B constant despite changes in external environments o Stimulus: something that excites an organism or part of an organism into a A function or action L Brain o Response: behavior or function that results from a stimulus A o Feedback inhibition: process in which the product or result stops or limits the N process C II. Interdependence of organ systems in homeostasis Sweat Chills E A. (Feedback loops ) promote homeostasis o Balancing Human Body Temperature: Systems that work together are the nervous system, integumentary system (skin), and muscular system Feedback loop: drop in temperature→brain senses temperature change→ muscles contract (shivering)→goose bumps form on skin→ body temperature regulates→brain senses temperature change o Balancing water content of the blood and body Systems that work together are the nervous, circulatory and excretory, and integumentary (skin releases water in sweat) Feedback loop: high amount of water goes into the kidney from the blood→sensed by the brain→kidneys→release water→water content of the blood is restored to normal→brain o Balancing sugar content of the blood Systems that work together: Nervous system; endocrine system (the organ is the pancreas; insulin is the hormone); circulatory system; digestive system Feedback loop: Blood sugar is high→brain senses change in blood glucose (sugar)→pancreas→makes insulin→cells take up glucose→brain senses change in glucose o Balancing metabolism : metabolism is all of the chemical reactions of the body Systems that work together: the nervous system and the endocrine system ns o Ho rm on e Se ors Se L A Brain and rs Pancreas Ho rm on e N C E e on rm Ho ns o A rs excess water o ns Kidneys release Se L Thirst/Kidneys reabsorb water Se Ho rm on e rs nso B ors rs ns o Se Se E Blood sugar is HIGH rs C e on rm Ho N Blood sugar is LOW o ns Brain A Sens rs nso A Sens Se B Water content is HIGH Hunger/ Eat/ conserve i nsuli n Secrete insulin ors ns rs Se e on rm Ho Water content is LOW Feedback loop: low thyroxine produces low metabolism→sensors from the brain alert the hypothalamus→hypothalamus sends a hormone to the pituitary→the pituitary sends a hormone to the thyroid gland→the hormone thyroxine is released into the blood stream→thyroxine levels go to normal B. Regulation of homeostasis is the function of the nervous and endocrine systems Nervous Endocrine Function Respond to external and internal stimuli Control growth, metabolism, homeostasis Message Sensory neurons carry impulses caused by stimuli to hormones travel through the blood delivery the brain; motor neurons cause muscles or glands to act Systems it All Nervous system, and circulatory system works with: Structures Brain, spinal cord, sensory & motor neurons Glands Thalamus and hypothalamus: connection between the nervous system and endocrine Thalamus: sends messages to the brain Hypothalamus: hunger (glucose levels), thirst (water content) and body temperature Type of message, speed, and duration Nerve tissue is made of sensory neurons and motor neurons. Neuron parts are axon, cell body, and dendrite. Response is fast and short-lived (like e-mail); message is an electrochemical pulse along a neuron Epithelial tissue Chemicals called hormones travel through the blood; the duration of the response is long lasting (like letters through the post office) III. Nutrient absorption (digestive system): Glucose is burned up for energy in the body cells. Glucose comes from carbohydrates in foods like fruit, rice, bread, potatoes & pasta. The mouth, stomach and small intestine all help to break down carbohydrates. Enzymes in the mouth and small intestine help to break down carbohydrates to make glucose. The stomach continues carbohydrate digestion. The small intestine breaks the carbohydrates down into molecules of glucose. The glucose is absorbed into the blood (circulatory system) by villi in the small intestine. Glucose cannot leave the blood and enter fat or muscle cells if the glucose channels are closed. The pancreas detects an increase in glucose levels in the blood and pumps insulin into the blood. Insulin unlocks the glucose channels of the fat cells so cells can take up the glucose. The glucose levels in the blood fall as glucose is taken up by the body cells and muscles. The pancreas detects the falling blood glucose levels and switches off its release of insulin. ENZYMES Catalysts provide a site for chemical reactions. Catalysts in cells are proteins called enzymes. The molecules entering into reactions are called substrates. For a catalytic reaction to occur, a substrate must fit into a groove on the surface of the enzyme called the active site. The amount of energy needed to activate the reaction (activation energy) is reduced. Reactions occur faster. Enzymes pair with substrates, each with a specific substrate it can catalyze. Enzymes are not used up or destroyed. CELL REPRODUCTION AND DIFFERENTIATION UNIT CONTENT GUIDE I. DNA Replication DNA unwinds DNA separates to form two complementary strands Each DNA strand acts as a template for the new, complementary strand Using the principles of base-pairing, two complete, identical copies of the DNA molecule are created 1. Cell Cycle Interphase o Cell Growth, Cell performs functions o DNA Replication o Preparation for Mitosis Cell Division o Mitosis o Cytokinesis o II. Mitosis - cell division for somatic (body) cell production Cell division will be covered in terms of chromosome activity. Do not use names of phases. Cell has undergone DNA replication Chromatin condenses into chromosomes, nuclear membrane breaks down Chromosomes line up across the center of the cell Chromosomes separate and move to opposite poles Chromosomes unwind, nuclear membrane reforms Cell separates into two identical daughter cells, each with the same number of chromosomes as the original cell III. Meiosis – cell division for gamete (sperm or egg) cell production Cell division will be covered in terms of chromosome activity. Do not use names of phases. Cell has undergone DNA replication Each chromosome pairs with its corresponding homologous chromosome and the nuclear envelope breaks down, crossing over takes place Chromosomes line up across the center of the cell CODOMINANCE AND MULTIPLE Homologous chromosome pulled to opposite ends of the cell ALLELES Nuclear membrane reforms, cell separates into two daughter cells, BLOOD TYPE GENOTYPES each with half the number of chromosomes as the original cell A IAIA, IAi In each of these two cells B IBIB, IBi the nuclear membrane breaks down (DNA does not replicate again) AB IAIB Chromosomes line up in the center O ii Chromosomes separate and move to the opposite poles Chromosomes unwind, nuclear membrane reforms Cells separate into 2 daughter cells, each with half the number of chromosomes as the original cell Summary: 4 mature gametes produced in males; 1 mature gamete produced in females, each with half the number of chromosomes as the original cell IV. Reproduction and Embryology Sexual Reproduction – reproductive cells from male and female parents unite, in a process known as fertilization, to produce the first cell of the new organism (zygote) o The new individual will have characteristics from each parent Asexual Reproduction – the first cell of the new organism comes from one parent The new individual is identical to the parent. The new individual arises from that single cell through a process of cellular differentiation during the embryonic phase MULTIPLE ALLELES COAT COLOR IN RABBITS Full color (C) – brown (dominant to all other alleles) CC, Ccch, Ccch, Cc Chinchilla (cch) – gray (dominant to ch and c) cchch, cchcch, cchc Himalayan (ch) – mostly white (dominant to c allele) chch, chc Albino (c) – no color (recessive to all other alleles) cc o o o o o o HEREDITY CONTENT GUIDE I. Classic Mendelian Genetics Gregor Mendel is known as the father of genetics Different forms of a gene are called alleles - dominant vs. recessive Punnett squares are used to determine the possible genetic combinations between two parents. Dominant homozygous (DD) vs. heterozygous (Dd) vs. recessive homozygous (dd) Genotype vs. phenotype (with the ability to determine ratios) Students should be able to complete Punnett squares for monohybrid and dihybrid crosses. They should be able to analyze the gametes formed, giving phenotypic and genotypic ratios as well as other probability questions. Multiple alleles occur when there are more than two Alleles for a certain trait. Chinchilla rabbits – four alleles for coat color Human blood groups – three alleles for blood type Sex-linked traits Hemophilia - recessive Colorblindness - recessive Duchenne Muscular Dystrophy – dominant SEX LINKED INHERITANCE GENOTYPE PHENOTYPE GENDER XNXN Normal Female XNY Normal Male XNXn Normal (carrier) Female XnY Not normal Male XnXn Not normal Female Codominance occurs when both alleles contribute to the phenotype of an organism as in blood types. Sickle-Cell Anemia – Heterozygote has sickle and normal shaped red blood cells NANS o o o II. Human Genetics Autosomes (44) vs. sex chromosomes (2, the X and Y) Karyotypes are pictures of chromosomes arranged in homologous pairs by number. Students should be able to identify the following disorders by analyzing a karyotype: o Down Syndrome – Three copies of chromosome 21 o Turner’s Syndrome – Female with only 1 X chromosome o Klinefelter’s Syndrome – Male with XXY Mutations Mutations are changes in the genetic material. Point mutations involve changes in one or more of the nucleotide sequences. Substitution, in which one base is changed to another, usually affects no more than a single amino acid, if any. Insertion, in which a base is inserted into the sequence, will affect the amino acid with the insertion and all those following in the sequence. Deletion, in which a base is removed from the sequence, will affect the amino acid with the deletion and each amino acid following in the sequence. Chromosomal mutations involve changes in the number or structure of chromosomes. This will be discussed further in the “Heredity” unit. Many mutations are neutral, having little or no effect on the expression of genes. Generally, insertion and deletion which result in frame-shifts have the greater impact. Mutations in gametes or early in fetal development have greater impact than those in mature body cells. Mutations are the source of genetic variability in a species. Some may be highly beneficial. This will be discussed further in the “Evolution” unit. Harmful mutations may result in genetic disorders or cancer. Some mutations are genetically engineered to create new variations of an existing organism (seedless watermelons), to replace or correct defective genes, or to produce hybrids such as bacteria that can produce human insulin. Some environmental causes of mutations are UV rays, radiation, pollution, etc. V. Recombinant DNA from Genetic Engineering o Gene splicing: genetic engineering that makes recombinant DNA o Recombinant DNA: a combination of DNA cut from one organism and added to the DNA of another o Restriction enzyme: an enzyme that can cut DNA only in specific spots o The steps of gene splicing are shown in order from left to right. The scissors represent a restriction enzyme CONTENT GUIDE FOR PLANTS I. Transport System A. Nonvascular – does not have tubes to transport materials so plants are necessarily small, must live in water, and must have water to reproduce 1. materials (water) are absorbed across membranes 2. cannot exceed 2-3 cell layers thick, must remain small 3. no true roots, leaves, stems B. Primitive vascular: Ferns have vascular system but reproduce using spores or sperm that must swim, so must live near water and in moist environments B. Vascular – has tubes to transport materials 1. xylem and phloem tubes act as a transport system similar to the circulatory system of animals 2. have true roots, stems and leaves (definition of true is to have tubes) 3. vascular tubes provide support for the plant similar to the skeletal system of animals 4. function of xylem and how water moves in plants 5. function of phloem and how nutrients move in plants 6. size can vary greatly, very large like Sequoia trees or very small like grass II. Leaves A. Primary function of leaf is to produce food through photosynthesis. 1. blade exposure to sunlight – surface area ratio in varying environments 2. gas exchange through stomata in leaf, relate to environmental conditions 3. cross-section of leaf - function/adaptations such as cuticle, stomata, spongy mesophyll B. Structural adaptations to the environment: needle-like, broadleaf, succulent, spines, carnivorous, stolons III. Roots A. Primary functions of roots 1. absorb water and nutrients (true roots have tubes) 2. root hairs – increase surface area 3. anchorage of plant 4. rhizoids –primitive plants have root-like rhizoids (no tubes) that function similar to roots (moss) B. Structural adaptations to the environment 1. fibrous roots – branched and net-like; increased surface area to absorb water near surface over larger area; also prevent soil erosion 2. taproot – single long root (may have some small offshoots); small surface area but reach into water deeper underground; food storage (carrot, beet) 3. some plants are not rooted in soil such as epiphytes (orchids) and Spanish moss 4. mycorrhizae – mutualistic symbiotic association between the roots of plants and a fungus - known as mycorrhizae, aid plant in absorbing water & nutrients (increase surface area), critical in evolution of plants onto land IV. Stems A. Primary functions of stems 1. produce leaves, branches and flowers 2. hold leaves up to sunlight 3. transport substances between roots and leaves B. Structural adaptations to the environment: 1. vascular tissue (xylem and phloem) for conducting food and water through plant 2. modified stems store food: tubers (potatoes), bulbs (amaryllis), rhizomes (ginger), corms (gladiolus) V. Hormonal control auxins modify the growth of plants, especially root formation, bud growth, and fruit and leaf drop. cytokinins produced by the roots and traveling upward through the xylem, that promote tissue growth and budding and, on application, retard plant aging. gibberellins main action is to cause elongation of the stem ethylenes promotes the ripening of fruit VI.Tropisms gravitropism oriented growth with respect to the force of gravity; also called geotropism Phototropism the growth response of plant parts to the stimulus of light, producing a bending towards the light source thigmotropism) the directional growth of a plant, in response to the stimulus of direct contact VII.Reproduction (All Plants Undergo Both Sexual And Asexual Reproduction. It is not necessary to cover alternation of generations.) A. Need of Water for Sexual Reproduction in Plants 1. nonvascular plants and primitive vascular plants must have moisture present for the sperm to swim to the egg during the sexual reproduction phase and for the embryo to be kept moist B. Spores – nonvascular plants and primitive vascular plants reproduce by spores (small asexual reproductive structures) C. Seeds – embryo of a plant that is encased in a protective seed coat and surrounded by a food supply 1. Vascular plants have flowers or cones; developed pollination (pollen is carried the sperm to the egg so moisture is not needed) and seeds (allow the embryo to survive during dry conditions and protect the seed). This released plants from the need to have moisture present for reproduction. 2. uncovered seeds (naked seeds) – the gymnosperms - do not have a protective layer of tissue outside the seed coat, most produce seeds in female cones and pollen in male cones 3. covered seeds – the angiosperms - have a tissue layer outside the seed coat to protect the seed a. flower b. fruit 4. pollination 5. adaptations for germination a. dormancy b. temperature variations 6. seed dispersal – to ensure dispersal away from parent a. wind dispersal – all conifers, some angiosperms (grass, tumble weeds, dandelion) b. water dispersal – coconut c. animal – eat fruit and deposit seed (in fertilizer) or carry it on their body d. explosive – pea pods – explode and send seeds flying Plant Adaptations to various biomes Desert ROOT Tundra Rainforest Desert LEAF STEM Tundra Rainforest Desert Tundra Rainforest Special Adaptations carnivorous plants poisonous plants thorny plants fibrous roots for short lived plants – roots spread over wide area to absorb as much water as possible in rainy season deeper taproots can reach water supply deeper under ground during dry season roots all shallow, cannot grow into permafrost epiphytes live high in trees and can absorb water from the air through their roots; large trees sometimes have adventitious roots to help support the plant in moist soil leaves modified to be narrow or small or even into spine-like structures leaves may be lost during dry season stomata stay closed more during the day, cuticle thick leaves narrow or small leaves large with flat blades; numerous stomata that are often open sometimes modified to large “blade” with chloroplast (cactus), most trees stunted plants very small; willow tree only often very tall to reach light above forest canopy must get minerals from organisms they trap because the soil is too poor to have the nutrients they need poison made by the plant prevents herbivores from eating them thorns help prevent herbivores from eating them Re-read your evolution unit 8 test review, and your unit 9 ecology notes.