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Year 10 Science Revision Booklet WHANAUMAITANGA- GENETICS REVISION AND QUESTIONS 2015 Key words: Nucleus Sperm Zygote Phenotype Homozygous Cytoplasm Egg Gene Cells Heterozygous Cell Membrane Meiosis DNA Selective Breeding Chromosomes Mitosis Allele Punnett Square Gamete Fertilisation Genotype Clones Key definitions to learn: Chromosome Gene DNA Allele Homozygous Heterozygous Genotype Phenotype Thread-like structures which carry the genetic information Sections of the chromosome. Each gene codes for a specific characteristic (trait) The molecule that contains genes. Different versions of a gene ( dominant version and recessive version) Both of an individual’s alleles are the same eg BB or bb Both alleles are different for the particular trait eg Bb The pair of alleles inherited by an individual i.e. Hh The physical expression of the genotype eg Blonde hair Key Learning Points: A cell is made of a nucleus embedded in cytoplasm surrounded by a cell membrane. Inside the nucleus are chromosomes. Chromosomes are made of DNA. Human cells contain 46 chromosomes in the nucleus of each cell except for sex cells (sperm and egg cell) and red blood cells. Sperm and egg cells have 23 chromosomes. The parents make their sex cells (sperm / egg cell) by a process called meiosis. Each cell has half the number of chromosomes as the original parent cell. The diagram below shows the key steps in human reproduction Year 10 Science Revision Booklet When a sperm and an egg cell join together at fertilisation their chromosomes mix to make 46 chromosomes in the new cell which is called a zygote. When this new cell forms it must copy itself to make many new ones. Each cell makes 2 new ones in a process called mitosis. All the cells made are identical. The table below that outlines some of the features of this process Name of Process Meiosis Fertilisation Mitosis Effect on Chromosomes Halves the number in new sex cell Joins the two half sets of chromosomes Keep the same number in new cell Product of this step Daughter cells are the sperm and egg zygote Purpose of this step Divide the chromosome pairs and make sex cells with half the genetic info. identical daughter cells To copy the chromosomes exactly and to make new cells for growth and repair Join chromosome pairs from different parents Boy or girl A male baby’s sex chromosome is XY and a female baby’s sex chromosome is XX All eggs contain only an X chromosome, but Sperms contain either an X or a Y chromosome. A boy baby forms when the egg cell is fertilised by a sperm containing a Y sex chromosome. A girl baby forms when an egg cell is fertilised by an X sperm. Punnet Squares This Punnet Square shows the male parent (XY) and female parent (XY). XY X Y X XX XY X XX XY XX Every time a child is born there is a 50% chance that the child is female. Website URL for revision: http://www.bbc.co.uk/schools/gcsebitesize/science/21c/genetics/ Year 10 Science Revision Booklet Method Selective breeding Description Advantages Disadvantages Breeding an organism that has a desirable trait with another so that the desirable trait is passed to the next generation Producing an organism with Continuous in-breeding and the right characteristics and selective breeding of particular genes runs the risk of losing It is less costly to small scale some of the other genes from farmers. the gene pool altogether, which is irreversible (This reduces the genetic pool and variation of this organism, which increases the chance of all the organisms being drastically reduced by one disease or responding to environmental change) You can only cross two related species In biotechnology, obtaining a group of genetically identical cells from a single cell; making identical copies of a gene An advantage is that many organisms could be efficiently produced in a short time (although not true with animals yet). This is especially true for plants which take a long time to grow and produce seeds. The possibility of producing not a complete body but just an organ to save the life of a human being who requires the transplant of that organ. A critically endangered species could benefit from cloning. A disadvantage is that they are genetically identical and drastic changes in the environment or diseases may wipe them out since they may all be susceptible to these. Very expensive and resource heavy to clone animals. Side effects may be harmful to the organism. Unethical. Genetic engineering Taking a specific section of DNA and inserting it into the DNA of another organism We can create SPECIFIC new products Much faster than selective breeding, you can express a trait in one generation You can cross two completely unrelated species The products produced can be lifesaving, eg insulin, golden rice It is more expensive than artificial selection Ethical implications of ‘playing god’ What happens if a new product escapes into the ecosystem? Unintentional consequences Assisted reproductive Technology that helps Gives equal opportunity for all couples to have offspring Unequal availability to these technologies (due to wealth) Cloning Year 10 Science Revision Booklet technologies infertile eg IVF couples to reproduce With these new technologies we have the ability to remove undesirable traits and diseases Ethical problems, how much should be ‘choose’ our traits Which diseases do we consider ‘too bad to be born’ Revision Questions: 1. Draw a generalised animal cell and label the following parts: Cell membrane, nucleus, chromosomes, cytoplasm. 2. Fill in the blanks: Our bodies are made up of trillions of c_________. Each cell has a n____________. In the nucleus there are 46 or 23 pairs of c__________________. Sections of c________________ are called g______________. Different versions of the same gene are called a______________. 3. Discuss the relationship between chromosomes, DNA, genes and alleles. ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… 4. Compare and contrast Selective Breeding and Cloning. What are the similarities and differences, and what are the advantages and disadvantages of each? ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… ………………………………………………………………………………… Year 10 Science Revision Booklet Draw a mind map for this unit: Add to it, as you develop your learning. Relationship from Cells to Alleles: Selective Breeding vs Genetic engineering Similarities: Differences: Genetics From Gametes to Zygote. Cell Division: Mitosis Well done you have completed another revision unit. Now reflect on how you can improve further: Which aspects of the unit do I need to revise more carefully? Which aspects of the unit do I need help with? How will I seek this help?