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LIFS 241 EXAM I
11-Feb-2004
Name:_____________________________
1
The internal environment to tissue cells in a human body is ____.
A. the cytoplasm
C. interstitial fluid surrounding the cells
B. abdominal and thoracic cavities
2
How much blood does an average-size man have?
A. 1-2 liter
C. 5-6 liter
B. 3-4 liter
D. 7-8 liter
3
Blood has all of the following functions except
A. nutrient transport.
B. heat distribution.
C. clotting.
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D. hormone production.
E. pH buffering
The blood has all of the following properties except _____.
A. pH 7.35-7.45
C. 38 C
B. B. 280-295 mOsm
D. less viscose than water
5
What percent of total blood can a healthy adult donate each time without adverse
effects?
A. 10%
D. 40%
B. 20%
E. 50%
C. 30%
6
The formed elements of the blood include all of the followings except ____.
A. plasma proteins
C. neutrophils
B. erythrocytes
D. platelets
7
What percent of the blood is plasma?
A. ~10%
D. ~70%
B. ~30%
E. ~90%
C. ~50%
8
After birth, the blood cells are generated primarily in
A.
the yolk sac.
D. red bone marrow
B.
the spleen.
E. the heart
C.
the liver
9
Which of the following cell type is the most abundant among all blood cells ?
A. neutrophils
D. eosinophils
B. erythrocytes
E. basophils
C. lymphocytes
10
The erythrocytes contain ____.
A. nuclei
B. hemoglobins
C. mitochondria
LIFS 241 EXAM I
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11-Feb-2004
Oxygen binds to ___.
A. alpha globin
Name:_____________________________
B. beta globin
C. heme groups
Each hemoglobin molecule can carry a maximum of ___ oxygen molecules.
A. one
B. two
C. three
D. four
13
Which molecules can compete with oxygen for the same binding site in
hemoglobin and cause severe problems?
A. carbon dioxide
B. carbon monoxide C. nitrogen
D. hydrogen
14
Red and white blood cells derived from ___ type of stem cells.
A. the same
B. different
15
Which hormone stimulates red blood cell production?
A. angiotensin
C. erythropoietin
B. aldosterone
D. prolactin
16
Erythropoiesis is stimulated when blood ____ content is low.
A. glucose
B. pressure
C. NaCl
D. oxygen
17
The ____ is especially involved in breaking up old erythrocytes and disposing of
the cellular remains.
A. spleen
B. bone marrow
C. lung
18
White blood cells serve to
A. transport carbon dioxide.
B. initiate blood clotting.
C. regulate erythropoiesis.
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D. heart
E. kidney
D. transport nutrients.
E. defend the body against pathogens.
The most abundant leukocytes in normal circulating blood are
A. eosinophils.
B. basophils.
C. neutrophils.
D. monocytes.
E. platelets.
20
ABO blood type is determined by specific glycoproteins (agglutinogens) which
are located on ___.
A. cytoplasm of erythrocytes
D. plasma membrane of leukocytes
B. plasma membrane of erythrocytes E. membrane of platelets
C. cytoplasm of leukocytes
LIFS 241 EXAM I
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11-Feb-2004
Name:_____________________________
Type AB blood contains ___.
A.
A agglutinogens plus B agglutinins
B.
both A and B agglutinogens plus both A and B agglutinins
C.
A agglutinogens
D.
O agglutinogens plus A and B agglutinins
E.
B agglutinogens and A agglutinins
22
What happens when a type AB blood is transfused into the blood stream of a
type B person?
A. agglutination of the donor’s erythrocytes
B. agglutination of the recipient’s erythrocytes
C. aggregation of the donor’s erythrocytes with the recipient’s erythrocytes
D. aggregation of the donor’s leukocytes with the recipient’s leukocytes
E. agglutination of the donor’s leukocytes
23
Transfusion with wrong blood can cause death due to ___.
A. the loss of leukocytes
C. bleeding
B. blockage of blood vessels by erythrocyte aggregates
24
Which Rh-positive new-born baby does not suffer from hemolytic disease if the
mother is Rh-negative?
A. the first child
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B. the second child
The normal white blood cell count (WBC) is ____.
A. 1,000-4,000/l
B. 4,000-11,000/l
The primary function of leukocytes is to ____.
A. transport oxygen
B. stop bleeding
C. the third child
C. 11,000-100,000/l
C. phagocytize pathogens
Which of the following is not involved in hemostatsis (stoppage of bleeding) ?
A. platelet plug formation
D. constriction of the blood vessel
B. agglutination
E. conversion of fibrinogen to fibrin polymers
C. clot formation
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Blood clot is not formed in unbroken blood vessels due to two of the following
factors.
1) fast blood flow
2) smooth inner surface of blood vessels 3) high leukocyte count
4) high platelet count 5) high erythrocyte count
A. 1 and 2
B. 2 and 3
C. 2 and 5
D. 3 and 4
E. 1 and 5
LIFS 241 EXAM I
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11-Feb-2004
Name:_____________________________
Platelets have all of the following properties except that ____.
A. platelets are fragments of megakaryocytes.
B. platelets aggregate at broken blood vessels
C. platelets help repair broken blood vessels.
D. platelets kill bacteria.
E. platelets facilitate coagulation
Select the right sequence of phases in a cardiac cycle
A. isovolumetric ventricular relaxation---atrial contraction---ventricular filling--isovolumetric ventricular contraction---ventricular ejection
B. atrial contraction---ventricular filling---isovolumetric ventricular contraction--ventricular ejection---isovolumetric ventricular relaxation
C. ventricular filling---atrial contraction---isovolumetric ventricular contraction--ventricular ejection---isovolumetric ventricular relaxation
D. ventricular filling---atrial contraction---isovolumetric ventricular relaxation--ventricular ejection---isovolumetric ventricular contraction
E. atrial contraction---ventricular filling---isovolumetric ventricular relaxation--ventricular ejection---isovolumetric ventricular contraction
31
Point out the correct sequence of blood flow
A. vena cava  right atrium  right ventricle  pulmonary artery 
pulmonary veins  left atrium  left ventricle  aorta
B. left ventricle  left atrium  aorta  vena cava  right atrium right
ventricle  pulmonary artery  pulmonary veins
C. left ventricle  right ventricle  aorta  vena cava  right atrium 
pulmonary artery  pulmonary veins  left atrium
D. left ventricle  pulmonary artery  right ventricle  aorta  vena cava 
right atrium  pulmonary veins  left atrium
32
Where are natural pacemaker cells are located?
A. AV node B. SA node C. ventricles D. His bundle
33
What structure allows action potentials to be conducted from one myocyte to
another?
A. Mitochondria
C. sarcoplasmic reticulum
B. pores in intercalated discs
D. thick filaments
34
Where is the conduction velocity the slowest?
A. atria
C. Purkinje fibers
B. ventricles
D. AV node
LIFS 241 EXAM I
11-Feb-2004
Name:_____________________________
35
How many times is ventricular contraction triggered by one electrical impulse
generated in SA node normally?
A. once
C. three times
B. twice
D. many times
36
Excitation is defined as ____.
A.
the generation of action potentials
B.
the shorting of muscle fibers
C. contraction
37
Migration of leukocytes following trail of inflammatory molecules is called ___.
A.
margination
C. chemotaxis
B.
diapedesis
D. phagocytosis
38
Engulfing pathogens into leukocytes is called ____.
A. margination
C. chemotaxis
B. diapedisis
D. phagocytosis
39
Electric impulses are conducted to ventricular muscles normally via ____.
A. regular cardiac muscle cells
C. Purkinje fibers
B. blood
D. A, B, and C
40
Which of the following condition causes a decrease in the pumping efficiency of
the heart?
A. sequential contraction of atria and ventricles
B. slow conduction of electric impulses in the ventricles
C. slow conduction of electric impulses in AV node
D. simultaneous contraction of ventricular muscles
41
The amount of blood (ml) ejected by one ventricle within one minute is defined
as ___.
A. stroke volume
D. cardiac output
B. preload
E. afterload
C. ejection fraction
42
ECG is ___.
A. the recording of action potentials generated by a single myocyte
B. applied to the detection of cardiac ischemia
C. applied to the measurement of arterial blood pressure
43
QRS complex corresponds to ___.
A. depolarization of atria
B. depolarization of ventricles
C. repolarization of ventricles
D. depolarization of AV node
LIFS 241 EXAM I
11-Feb-2004
Name:_____________________________
44
ECG can be used to reveal all of the following except ___.
A. arrhythmias
C. ventricular hypertrophy
B. ischemia
D. heart murmurs
45
Which of the following statement about the first heart sound is false?
A. The first heart sound occurs at the opening of semilunar valves
B. The vibration of AV valves contributes to the first heart sound.
C. The first heart sound is generated when the blood bounced back from the AV
valves.
D. The vibration of ventricular walls makes the first heart sound louder.
E. The first heart sound is longer than the second heart sound.
46
Preload on left ventricular muscles is determined by ____.
A. end diastolic volume of left ventricle
D. aortic arterial pressure
B. end systolic volume of left ventricle
E. stroke volume
C. pulmonary arterial pressure
47
Afterload on left ventricular muscles is determined by ___.
A. end diastolic volume of left ventricle
D. aortic arterial pressure
B. end systolic volume of left ventricle
E. stroke volume
C. pulmonary arterial pressure
48
Given that end diastolic volume, end systolic volume, and heart rate are 160 ml,
80 ml, and 80 beats/minute, respectively, cardiac output should be ____.
A. 80 ml
B. 160 ml
C. 240 ml
D. 640 ml
E. 6,400 ml
49
Contractility is _____.
A. the intrinsic strength of cardiac muscles
B. dependent on preload
C. dependent on afterload
50
Can an increase in heart rate result in a greater cardiac output?
A. Yes, it always can.
B. No, it cannot.
C. Yes or no, it depends on the level from which heart rate increases.
51
Sympathetic nervous system regulates ____.
A. both heart rate and contractility
C. contractility only
B. Heart rate only
D. neither heart rate nor contractility
52
The baroreceptors mediate ___ when blood pressure drops suddenly.
A. an increase in heart rate
B. a decrease in cardiac contractility
C. a decrease in conductivity of AV node
LIFS 241 EXAM I
11-Feb-2004
Name:_____________________________
53
Proprioceptors are involved in regulating cardiac functions mainly ____.
A. at resting state
B. during heavy physical activities C. during hemorrhage
54
Chronotropic effects refer to those causing a change in ___.
A. heart rate
B. contractility
C. conductivity
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A.
B.
C.
D.
Starling-Frank mechanism refers to ___.
 ventricular filling   stroke volume
 ventricular filling   stroke volume
 ventricular filling   stroke volume
 afterload   stroke volume
LIFS 241 EXAM I
11-Feb-2004
Name:_____________________________
KEY 241 Exam 1 Spring 2004
1C
11C
21C
31A
41D
51A
2C
12D
22A
32B
42B
52A
3D
13B
23B
33B
43B
53B
4D
14A
24A
34D
44D
54A
5A
15C
25B
35A
45A
55A
6A
16D
26C
36A
46A
7C
17A
27B
37C
47D
8D
18E
28A
38D
48E
9B
19C
29D
39C
49A
10B
20B
30C
40B
50C