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Biology of Cells & Tissues Dr. Campbell Dr. Farmer Exam 1 Summer 2001 Name___________ Form A 1. Epithelial tissue: a. rests on a basal lamina b. has polarized cells c. is well vascularized d. a and b e. a, b, and c 2. Glands that secrete by the death and rupture of entire cells are said to secrete by the ______ method. a. apocrine b. holocrine c. merocrine d. none of the above 3. Epithelia are classified based on the number of layers of cells and the shape of the deepest layer. a. true b. false 4. The epithelium lining blood vessels is: a. simple squamous b. stratified squamous c. mesothelium d. endothelium 5. A pseudostratified epithelium is found in the: a. tubules of the kidney b. urinary bladder c. thyroid gland d. trachea 6. Stratified squamous nonkeratinized epithelium is found lining the esophagus. a. true b. false 7. The epithelium on the surface of intestinal villi is: a. simple cuboidal b. simple columnar c. stratified cuboidal d. stratified columnar Biology of Cells & Tissues, Exam 1, Summer 2001. 1 Matching: a. b. c. Match the word to its definition. Each choice is used only once. Anabolism Catabolism Metabolism 8. The sum total of all the chemical reactions occurring within cells. 9. That portion of metabolism that deals with biosynthesis. 10. That portion of metabolism that deals with breaking down food molecules to obtain energy. 11. The three biochemical paths that are linked to produce ATP from the breakdown of food molecules are referred to collectively in the process called _____. a. anaerobic respiration b. aerobic respiration c. photosynthesis d. none of the above 12. The type of bond that is used to join individual fatty acids to a glycerol of a triacylglycerol is called a(n) _____. a. phosphoester b. peptide bond c. ester bond d. glycosidic bond 13. The type of bond that is formed when to monosaccharides are joined to produce a disaccharide is called a(n) ____. a. phosphoester b. peptide bond c. ester bond d. glycosidic bond 14. The type of bond forming the backbone of a nucleic acid is called a(n) ____. a. phosphoester b. peptide bond c. ester bond d. glycosidic bond Biology of Cells & Tissues, Exam 1, Summer 2001. 2 Matching: a. b. c. Match the metabolic pathway to its location within the eukaryotic cell. Glycolysis Tricarboxylic Acid Cycle (TCA) ETS 15. Components located in the inner mitochondria membrane. 16. Enzymes located in the matrix of the mitochondria. 17. Enzymes located in the cytoplasm. 18. The monomeric units of nucleic acids are ______. a. peptides b. nucleotides c. monosaccharides d. triacylglycerols 19. What property of water allows it to form solvation shells around both cations (+) and anions (-)? a. its extremely dense atomic structure b. the difference in dielectric constants for H and O c. the angle of the H-O-H bonds form d. the polar covalent nature of the Oxygen to Hydrogen bonds 20. Lactose is made up of ___ and ____. a. glucose and fructose b. glucose and maltose c. glucose and galactose d. glucose and glucose 21. The polysaccharide, which is stored in human cells like the hepatocytes of the liver is called _______. a. starch b. lignin c. cellulose d. glycogen 22. The common form of lipid storage molecule in the adipose tissue is ______. a. triacylglycerol b. cholesterol c. sphingolipids d. ganglosides Biology of Cells & Tissues, Exam 1, Summer 2001. 3 23. The role of the nucleic acid known as DNA is to ____. a. form a structural support in the nucleus b. store the information it takes to run the cell c. remove the interference produced by RNA d. facilitate the transport of RNA out of the nucleus 24. Proteins destined to be functional inside the nucleus must have a _____ amino acid sequence in order to be brought in to the nucleus following translation. a. signal sequence b. mitochondrial sequence c. nuclear localization signal d. peroxisomal localization signal 25. The arraying of pictures of the metaphase chromosome in an organized fashion whereby the larger chromosomes are first and the smaller chromosomes come later produces a ______. a. nuclear matrix b. nuclear cisternae c. karyotype d. prysbyopia 26. The area on the nucleus where the rRNA genes are localized and highly expressed and also where these expressed products are undergoing subassembly of the ribosomes is called the _____. a. nuclear pore complex b. nucleolar organizing region c. nucleoplasm d. nuclear envelope 27. Pick the unusual characteristic of the nuclear envelope. a. it’s a lipid bilayer b. its composed of a double lipid bilayer c. its composed entirely of proteins d. none of the above 28. Which of the following is the primary function of the plasma membrane of cells? a. contains the information to make mitochondria b. allows free passage of all substances c. provides energy to the cell d. forms the barrier between inside and outside the cell Biology of Cells & Tissues, Exam 1, Summer 2001. 4 29. The difference between simple diffusion and facilitated diffusion is that there is a ____ involved in facilitated diffusion, but not in simple diffusion. a. protein b. glycolipid c. nucleic acid d. polysaccharide 30. The current model for the cell membrane describing the interaction of the lipids and proteins of the membrane is called the ______. a. Singer Nicholson model b. Rogers and Hart model c. Fluid Mosaic model d. none of the above 31. Which of the following is a function of smooth ER? a. drug detoxification b. energy generation c. protein synthesis of secreted proteins d. glycolysis 32. Clathrin is involved in _______. a. receptor mediated endocytosis b. exocytosis c. pinocytosis d. phagocytosis 33. Processing in the Golgi would involve which two tasks? (Pick two letters on your scantron.) a. methylations b. glycosylations c. removing any attached lipids from proteins d. sorting proteins into functional groups 34. Which type of inclusion would be more energy dense? a. glycogen b. lipid droplets 35. The primary microtubule organizing centers (MTOC's) of eukaryotic cells are the ______. a. nucleolus b. centrioles c. NOR's d. Golgi Complex Biology of Cells & Tissues, Exam 1, Summer 2001. 5 36. The basal body of a cilium has a _____ structure. a. 9+0 b. 9+2 c. 9+3 d. 9+1 37. The supporting structure for a stereocilium is based on _____. a. microtubules b. intermediate filaments c. actin filaments d. none of the above 38. The structure of the axoneme of a cilium is ______. a. 9+0 b. 9+2 c. 9+3 d. 9+1 39. Which component powers the movement of the cilium? a. dynein b. axonemal dynein c. kinesin d. axonemal kinesin 40. Which of the following is a communicating cell junction? a. desmosome b. hemidesmosome c. tight junction d. intermediate junction e. gap junction 41. Which of the following junctions is typically nearest the apical surface of the columnar epithelium cells of the jejunum a. desmosome b. hemidesmosome c. tight junction d. intermediate junction e. gap junction 42. Which of the following junctions is typically found on the basal surface of the columnar epithelium cells of the jejunum a. desmosome b. hemidesmosome c. tight junction d. intermediate junction e. gap junction Biology of Cells & Tissues, Exam 1, Summer 2001. 6 43. Which of the following tissues is one which is continuously in the cell cycle? a. hepatocytes b. epithelia c. cardiac muscle cells d. neurons 44. When a cell exits the cell cycle it is said to enter _____. a. G1 b. G2 c. S d. M e. G0 45. Which phase in the cell cycle involves the replication of the DNA? a. G1 b. G2 c. S d. M e. G0 46. Checkpoints within the cell cycle help to maintain the integrity of the cell. Which group of proteins help in this process by generally increasing during G1,S,G2? a. phosphatases b. cyclins c. maturation promoting factor d. actin 47. Which of the following increases in concentration during the M phase? a. phosphatases b. cyclins c. maturation promoting factor d. actin 48. Which of the following is a protein that is preventing the progression of G1 to S phase when there is damage to the DNA? a. P53 b. MPF c. Kinases d. Cyclins 49. Heavily damaged cells will eventually reach a point where they will begin the series of events that leads to ______. a. receptor mediated endocytosis of repair proteins from neighboring cells b. apoptosis c. secretion of hormone SOS signals d. none of the above Biology of Cells & Tissues, Exam 1, Summer 2001. 7 50. In mitosis, which phase is marked by the separation of the centromeres and the beginning of the movement of the chromosomes to the opposite poles. a. prophase b. metaphase c. anaphase d. telophase END OF EXAM Biology of Cells & Tissues, Exam 1, Summer 2001. 8