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Dosing regimens of selective serotonin reuptake inhibitors (SSRIs) for anxiety disorders (Table 8.1)* Drug Initial daily dose† Maximum daily dose citalopram 10 mg 40 mg escitalopram 5 mg 20 mg fluoxetine 10 mg 80 mg fluvoxamine 50 mg 300 mg‡ paroxetine 10 mg 60 mg sertraline 25 mg 200 mg * Not every SSRI has Australian TGA approval for use for each anxiety disorder; however, there is insufficient evidence to differentiate between efficacy of the individual SSRIs. † Dose orally in the morning after food. Increase dose according to tolerability and patient response. ‡ Doses above 150 mg daily may be given in 2 divided doses for better tolerability. Therapeutic Guidelines Limited (www.tg.org.au) is an independent not-for-profit organisation dedicated to deriving guidelines for therapy from the latest world literature, interpreted and distilled by Australia’s most eminent and respected experts. Reproduced with permission from Psychotropic Expert Group. Dosing regimens of selective serotonin reuptake inhibitors (SSRIs) for anxiety disorders (Table 8.1) [revised 2013]. In: eTG complete [Internet]. Melbourne: Therapeutic Guidelines Limited; 2013.