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Phar. Discussion week 13 SSRIs (selective serotonin reuptake inhibitors) stimulate certain serotonin receptors that can cause a decrease in dopamine and norepinephrine in the brain, which can have an effect on your libido. She has been on an antidepressant SSRIs for 6 months and all SSRIs have been documented as having sexual side effects. Depression itself can cause a low libido and is very common in people with depression. Risk versus benefits will have to be weighed. Not all antidepressants have sexual side effects. She needs to report her issues with her doctor and they can discuss the various options. Stopping the medicine usually solves the sexual problem but should only be under doctor’s supervision. Lowering the dose, switching to a nonSSRI drug are other options. Changing to Wellbutrin or adding it to an SSRI can help counteract sexual side effects. Wellbutrin can actually increase one’s sex drive. http://www.foxnews.com/health/2011/10/10/antidepressant-killing-your-libido-not-for-long/ http://www.medicinenet.com/script/main/art.asp?articlekey=51118 Pharmacology and the Nursing Process, 6th Edition