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Chapter 1 Biology 25: Human Biology Prof. Gonsalves Los Angeles City College Loosely Based on Mader’s Human Biology,7th edition Chapter 1 Introduction: The Scientific Study of Life Biology: The study of life. Greek origin: Bio: Life Logos: Study of I. Life is based on many structural levels Levels of biological organization: – Atoms – Molecules – Subcellular organelles – Cells – Tissues* – Organs* – Organ systems* – Organism: May consist of a single cell or a complex multicellular organism. * Level of organization not found in all organisms Levels of organization beyond organism: • Population: Group of organisms of the same species that interact with one another. • Community: Several different populations living together in same area (e.g.: lake, forest, jungle). • Ecosystem: Interactions of community with non-living environment (air, water, soil). • Ecosphere: All ecosystems on planet earth. Includes: – – – – Biosphere: All biological communities on earth. Atmosphere (air) Hydrosphere (water) Lithosphere (crust) Common features of all organisms: 1. Cells: Basic structural and functional unit of life. Genetic information contained in DNA. 2. Growth and Development: • Growth: Occurs by an increase in cell size, cell number, or both. • Development: Changes that take place during an organism’s life. 3. Energy use and metabolism: • All organisms must take in and transform energy to do work, to live. • Metabolism: All chemical reactions and energy transformations essential for growth, maintenance, and reproduction. 4. Regulation • External environment may change, but internal environment remains fairly constant. – Homeostasis: Organisms constantly strive to maintain a “steady state” (e.g.: constant body temperature or blood pH) despite changes in the internal and external environment. – Metabolism is regulated by homeostatic mechanisms. 5. Movement: • Internal movement: Characteristic of all life. • Locomotion: Self-propelled movement from point A to point B. Not observed in all life forms. 6. Respond to environmental stimuli: Organisms respond to internal and external changes (visual stimuli, temperature, light, sound, pressure, etc.). 7. Order: Organisms are highly organized, when compared to nonliving environment. 8. Reproduction: Organisms come from other organisms. Reproduction may be sexual or asexual. 9. Evolutionary adaptation: Populations, not individuals, “evolve” or change over many generations so they can survive in a changing world. Evolution is the core theme of biology – Charles Darwin: Wrote “On the Origin of Species by Means of Natural Selection” (1859) in which he proposed the theory of evolution. Evidence that led to the principle of evolution: – Fossils: Most species that ever existed are extinct; appear to be gradual progression – Artificial selection of domestic/farm animals – Adaptations: Organisms appear uniquely suited to their environment (especially in Galapagos). • Darwin’s finches are a classic example The theory of evolution by natural selection: 1. Genetic Variation: Due to genetic differences there is variation within a population (size, color, structure, etc.). These differences can be passed on to an individual’s offspring. 2. Overproduction: Many more organisms are born, than those that survive and reproduce. 3. Limits on population Growth: Limited resources (food, water, space, sunlight, etc.) creates competition 4. Differential reproduction: Organisms with features that help them compete will be more likely to survive and reproduce. Natural Selection Changes Populations Theory of evolution by natural selection: Consequences of natural selection Over time, the characteristics of a population will “evolve” and assume those features that are “naturally selected”. What is the heritable molecule with the blueprints for the traits of an organism? –DNA: Deoxyribose nucleic acid All life can be classified taxonomically – Taxonomy: The branch of biology concerned with naming and classifying organisms – Most Biologists Recognize Five Kingdoms: Monera, Protista, Plantae, Fungi, and Animalia 1. Kingdom Monera (Procaryotae): Most widespread organisms. • Procaryotes (“Before nucleus”): – Lack nuclear membrane around DNA. – Lack membrane bound organelles (mitochondria, chloroplast, golgi, endoplasmic reticulum). • Unicellular: Single celled organisms. • Have a cell wall. • Include: Bacteria. Kingdom Prokaryotae: Bacteria lack nucleus and membrane bound organelles Five Kingdoms of Living World: 2. Kingdom Protista: • Eucaryotes (True nucleus): – Have nuclear membrane around DNA. – Have membrane bound organelles (mitochondria, chloroplast, golgi, endoplasmic reticulum). • Unicellular or simple multicellular. • Most are larger and more complex than bacteria. • Some have cell walls, others don’t. • Some make their own food (phothosynthetic), others must eat other organisms. • Include: Protozoa, algae, slime molds. Kingdom Protista: Eucaryotic Unicellular or Simple Multicellular Organisms Five Kingdoms (Continued): 3. Kingdom Fungi: • Most are multicellular. • Eucaryotes: – Have nuclear membrane around DNA. – Have membrane bound organelles (mitochondria, chloroplast, golgi, endoplasmic reticulum). • Have cell walls. • Heterotrophs: Obtain food from other organisms. • Most are decomposers, which absorb food from dead organisms. • Include: Mushrooms, yeasts, and molds. Five Kingdoms (Continued): 4. Kingdom Plantae: • Complex multicellular organisms. • Cellulose cell walls. • Eucaryotes: Have nuclear membrane around DNA and membrane bound organelles. • Autotrophs: Convert sunlight, water, and carbon dioxide into food through photosynthesis. • Other features: – Waxy cuticle that prevents water loss. – Multicellular sex organs. – Openings in leaves and stems for gas exchange (stomata). • Include: Trees, flowering plants, and mosses. Five Kingdoms (Continued): 5. Kingdom Animalia: • Complex multicellular organisms. • Lack cell walls. • Eucaryotes: Have nuclear membrane around DNA and membrane bound organelles. • Heterotrophs: Obtain chemical energy from living sources. Eat other organisms for nourishment. • Features of complex animals: – High degree of tissue specialization and body organization. – Locomotion. – Well developed sense organs, nervous system, and muscles. • Include: Sponges, worms, insects, and vertebrates. Interdependence of Biological Groups 1. Producers or Autotrophs: • Self-nourishing organisms (plants, algae, etc.). • Produce food from simple raw materials. • Most carry out photosynthesis: CO2 + H2O + Sunlight -----> Food + Oxygen • Depend on nonproducers for carbon dioxide 2. Consumers • Mainly animals. • Heterotrophs that obtain food directly or indirectly from producers. • Carry out cellular respiration: Food + Oxygen -----> CO2 + H2O + ENERGY Gas exchange between producers and consumers helps maintain balance of life-sustaining gases in atmosphere. Interdependence of Biological Systems 3. Decomposers: • Some bacteria, fungi, and animals. • Recycle nutrients by breaking down products and bodies of dead organisms. • Process is vital because makes nutrients available for use by other organisms. • All organisms interact with each other and the environment they live in. • Interactions between producers, consumers, and decomposers are essential to maintain proper conditions for life on earth. Photosynthesis Helps Counteract the Greenhouse Effect – The earth’s atmosphere contains about 0.03% of carbon dioxide. – Carbon dioxide traps solar energy in the atmosphere, making the earth about 10oC warmer than it would otherwise be. – Since the mid 1800s, the atmospheric levels of carbon dioxide have risen steadily due to the burning of fuels and forests. – The “Greenhouse Effect” refers to the global warming that is caused by increased atmospheric carbon dioxide levels. – Global warming may cause polar ice caps to melt, which in turn could cause massive coastal flooding and other problems. – Plants use up about half of carbon dioxide generated by humans and other organisms. Greenhouse Effect: Heat is Trapped by Carbon Dioxide SCIENCE AS A METHOD OF INVESTIGATION Scientia (Latin): To know Science is a systematic way of thinking, answering questions, and solving problems. Steps of scientific method: 1. Observations 2. Question 3. Hypothesis 4. Predictions 5. Test predictions (Experiments) Results of experiments may: – Support (but not prove) hypothesis – Disprove hypothesis -----> Change hypothesis. Scientific method (Continued): Hypothesis: – Proposed explanation for observations – An “educated guess”, should be consistent with established facts – Capable of being tested, should generate predictions. – Falsifiable, may be proven false (but not proven true). Variables in an Experiment – Dependent Variable: What a scientist measures. – Independent variable: What a scientist controls or manipulates. – Standardized variables: What remains the same throughout experiment. E.g.: Age, sex, race, nutrition, health, etc. Control Treatment: – Independent variable is eliminated or set at a standard value. Levels of Treatment – Values set for the independent variable. Scientific method: Replication – Experiments are repeated numerous times. – Consistent results increases confidence in results. – Sample size: Larger sample sizes are generally better. Theory: – Hypothesis supported by a large body of observations and experiments. – Good theories relate previously unrelated facts and grow as new information is obtained. Principle: – A theory that over time has yielded true predictions. – Almost universally accepted. Law: – A principle of great basic importance. – Law of gravity or biogenesis.