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Bacteria in your pad – Translation from an article in « Le Temps » Newspaper Technology : Students from Lausanne are working on a new type of touchscreen integrating organic elements. They will present their project at the end of october at a competition organized by the prestigious MIT in Boston. [Fabien Goubet] A pressure on its envelope makes it Thus, the students have bacteria produce protective proteins that that emit light when we touch No respite for smartphones and rigidify its structure to limit this them. To take advantage of this, other pads. As soon as they stress. The mechanism by which it they used a microfluidic chip. This invaded our pockets and our living happens is but is rooms, some already think about Sakura Nussbaum her centimeters long, composed of the next step. Sakura Nussbaum teammates have studied it closer. PDMS, a carbon and silicium and her thirteen teammates, still uncertain, and a small plate a few They noticed that it involves a polymere Life protein named CpxR, which role is slightly malleable. The chip is Sciences at EPFL, are some of them. to stimulate the production of these made of 768 tiny cavities of a few « We are working on the design protective proteins. In the absence micrometers in diameter in which and the fabrication of a « BioPad », of pressure, CpxR is divided in two are placed bacteria with a little a touchpad working with the help distinct and inactive parts. These culture medium. « Each chamber of biological compounds, in this parts reassemble in case of pressure constitutes in a way one pixel », case bacteria that emit light when a on the bacterial envelope and indicates Axel De Tonnac, the pressure is applied on the screen », constitute the CpxR protein itself, microfluidics summarizes the young student. active this time. The team of crew. The students are currently Their its students based the concept of their verifying that their bacteria really less project on this mechanism. « We emit have modified applied on it. Here is where their Escherichia coli, so that it emits light work is. Of course, they are still when it is subjected to pressure », far away from a hypothetical « details BioPad », but the project only students in Bachelor project beginning, is but of only is no at encouraging. When we put bacteria under mechanical pressure, they don't stay inert but react to limit the consequences. It is the case for Escherichia coli, a very common intestinal bacteria. genetically Sakura luminescence Nussbaum. is ensured The by light which of structure specialist when of is the pressure is a started this summer. « We are still protein coming from glow worm, at the stage of proof of concept, the luciferase. This protein is « admits Axel De Tonnac, But our grafted » on the CpxR protein and objective now is to make sure emits light only when the two parts that are assembled. expected, and to present our everything works as work at the iGEM competition. » The whole team is going to fly to must persevere in their work. I am Boston, where the competition convinced that the screens of the international future will combine electronics and Genetically Engineered Machine (iGEM) will take place. Starting on the 30th of octobre and organized by the Massachusetts Institute of Technology (MIT), this competition reassembles 220 teams of students, from different specialities. It brings synthetic biology at honour, a discipline in which biologists work as engineers and standardized build biological compounds, « biobricks », which can be useful in the future for other researchers particular wanting function to give to living organisms. Naturally, the obstacles to the realisation of a screen are numerous. How to renew the culture medium once it is used ? How to control the multiplication of the bacteria without compromising the performance of electric circuits ? Bent Stumpe, retired from CERN and inventor of the first touchscreen in 1972, heard about the project. For him, they should not be impressed by this kind of inconvenients. « They absolutely biology », assures the researcher.