* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Slide ()
Survey
Document related concepts
Non-coding DNA wikipedia , lookup
Promoter (genetics) wikipedia , lookup
Transcriptional regulation wikipedia , lookup
Community fingerprinting wikipedia , lookup
Gene desert wikipedia , lookup
Point mutation wikipedia , lookup
Endogenous retrovirus wikipedia , lookup
List of types of proteins wikipedia , lookup
Gene therapy of the human retina wikipedia , lookup
Clinical neurochemistry wikipedia , lookup
Molecular evolution wikipedia , lookup
Personalized medicine wikipedia , lookup
Silencer (genetics) wikipedia , lookup
Gene therapy wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Gene regulatory network wikipedia , lookup
Transcript
Proposed genetic rearrangement of chromosome 11 in a subset of sporadic parathyroid adenomas. An inversion of DNA sequence near the centromere of chromosome 11 places the 5′-regulatory region of the PTH gene (also on chromosome 11) adjacent to the PRAD1 gene, whose product is involved in cell cycle control. This places the PRAD1 gene under the control of PTH regulatory sequences, which would be predicted to be highly active in parathyroid cells. (Redrawn, with permission, from Arnold A. Molecular genetics of parathyroid gland neoplasia. J Clin Endocrinol Metab. 1993;77:1109.) Source: Disorders of the Parathyroids & Calcium & Phosphorus Metabolism, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e Citation: Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e; 2013 Available at: http://mhmedical.com/ Accessed: August 03, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved