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Advanced Chemical Biology II (2017) Location: Room 121, Department of Chemistry, NTU Time: 9:10 ~ 12:10 pm Fridays Credit: 3 credits Coordinator: Hans Lin TA: 黃映晨 Date Topic Instructor 02/24 Specific labeling of biomolecules Hans Lin (IBC) 03/03 Activity-based protein profiling-I Hans Lin (IBC) 03/10 Activity-based protein profiling-II Hans Lin (IBC) 03/17 Natural products at a glance Tsung-Lin Li (GRC) 03/24 Building blocks and reactions in natural products Tsung-Lin Li (GRC) Spring break 03/31 04/07 Tsung-Lin Li (GRC) Antibiotics and development 04/14 Mid-term Exam 04/21 Introduction of expanding genetic code discovery Yang-Shih Wang (IBC) 04/28 Yang-Shih Wang (IBC) 05/05 Case study of protein synthesis with protein post-translational modifications and its applications Advance in incorporating non-canonical amino acids technology 05/12 Introduction of bioorthogonal chemistry and their application 05/19 Protein organic chemistry and applications for labeling and engineering. 05/26 Fluorescent probe development for bioimaging applications. 06/02 Students’ oral presentations 06/09 Final Exam Yang-Shih Wang (IBC) Jiun-Jie Shie (IoC) Jiun-Jie Shie (IoC) Jiun-Jie Shie (IoC) Grading scheme: Mid-term: 35%, Final exam: 35%, oral presentation: 30% Attendance: Unexplained absence: -3 of final grade (did not send notice to the TA before class) Late: -2 of final grade Absence without supporting document: -1 of final grade (if a student did not inform the course TA to excuse him/herself from the class before lecture starts, he/she has to provide a proof to the TA to explain his/her absence to the class.)