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Transcript
Structures of Amino Acids Amino Acid Name R = any number carbons in a hydrocarbon chain *CHIME plug-in required to view these images. A A b b r r Structure e e of R group (red) v. v. Comments Alanine ala A Neutral Non-polar Arginine arg R Basic Polar Asparagine asn N Neutral Polar Aspartic Acid asp D Acidic Polar Cysteine cys C Neutral Slightly Polar Glutamic Acid glu E Acidic Polar Glutamine gln Q Neutral Polar Glycine gly G Neutral Non-polar Histidine his H Basic Polar Isoleucine ile I Neutral Non-polar Leucine leu L Neutral Non-polar Lysine lys K Basic Polar Methionine met M Neutral Non-polar Phenyl-alanine phe F Neutral Non-polar Proline pro P Neutral Non-polar Serine ser S Neutral Polar Threonine thr T Neutral Polar Tryptophan trp W Neutral Slightly polar Tyrosine tyr Y Neutral Polar Valine Val V Neutral Non-polar Building and Folding a protein! Today you have been given a challenging task. Can you construct a polypeptide and fold it into a quaternary structure? You will be given a fictional ‘protein’ to construct that is 10 amino acids in length You will need to show all 4 stages of folding (primary, secondary both beta sheet and alpha helix) on your poster including any bonds that can form between the amino acids You will need to use the data sheet to help you, pay particular attention to the amino acids chemical structure and properties to help you identify which bonds may form Important! Remember that if your amino acid has acidic properties then it has a relatively negative charge, if your amino acid has basic properties then it has a relatively positive charge Polypeptide to construct: Cysteine, Glycine, Alanine, Methionine, Aspartic Acid, Glycine, Arginine, Lysine, Serine, Alanine Good Luck! Extension If you complete the above task then you can add a list of globular and fibrous proteins to your poster and briefly describe the difference in function between the two.