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FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Page 1 of 6 Department of Biotechnology LP: Sub Code BT6602 B.E/B.Tech/M.E/M.Tech : Biotechnology (VI Semeter) PG Specialisation : Biotechnology Sub. Code / Sub. Name : BT 6602 / Immunology Unit : I INTRODUCTION Regulation: 2013 Rev. No: 00 Date: 29/12/2016 (9 Hrs) Unit Syllabus: INTRODUCTION Cells of immune system. Innate and Acquired immunity. Primary and Secondary lymphoid organs. Antigens Chemical and Molecular nature, Haptens, Adjuvants, Types of immune responses, Antigen processing and presentation. Theory of clonal selection. Monoclonal antibodies – Principles and Applications. Objective: To know about the immune system Session No * Topics to be covered 1 Introduction to immunology 2 Cells of immune system 3 Innate and acquired immunity 4 Ref Teaching Aids PPT & BB T1(1-19), T2(30-40) T1(21-36) T2 (7-16) PPT, Video & BB Primary and secondary lymphoid organs T1(147-162), T2(40-43) PPT, Video & BB 5 Antigens: chemical and molecular nature T2 ( 77-81) PPT, Video & BB 6 Haptens and Adjuvants T1(80-83), T1(300-302), T2 (77-78,81) PPT, Video & BB 7 Types of immune responses T2(448-454) PPT & BB 8 Theory of clonal selection T2(16-18) PPT, Video & BB 9 Review - - PPT & BB Content beyond syllabus covered (if any) : Immunogenicity, Antigenicity, Immuno diffusion and Immunoelectrophoresis * Session duration: 50 minutes FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Page 2 of 6 Sub. Code / Sub. Name: BT 6602 / Immunology Unit : II CELLULAR RESPONSES (9 Hrs) Unit Syllabus: CELLULAR RESPONSES Development, maturation, activation and differentiation of T-cells and B-cells. TCR. Antibodies - Structure and Functions. Antibodies - Genes and Generation of diversity. Antigen-Antibody reactions. Antigen presenting cells. Major histocompatibility complex. Regulation of T-cell and B-cell responses. Objective: To study about the cellular responses of immune system Session No * 10 Introduction to cellular responses T2(11-14) PPT, Video & BB 11 Development, maturation of T-cells and B-cells T1(164-174), T2(245-257) PPT & BB 12 Activation, differentiation of T-cells and B-cells T1(164-174), T2(245-257) PPT, Video & BB 13 T-Cell Receptor Antibodies: structure and functions Antigen-antibody reactions T2(223-241) PPT, Video & BB T1(37-58), T2(84100) T2(145-164) 14 Antibodies: genes and generation of diversity T1(37-58), T2(111-135) PPT & BB 15 Monoclonal antibodies, principles and applications T1(84,120-125), T2(104-107,136) PPT, Video & BB 16 T2(207-2115) T2(206-209) T1(70-77), T2(189-205) PPT, Video & BB 17 Antigen presenting cells & Major histocompatibility complex Antigen processing and presentation 18 Regulation of T-cell & B-cell responses. T1(173-183), T2(15,16) T2 (292-297) PPT & BB Topics to be covered Content beyond syllabus covered (if any): * Session duration: 50 mins Ref Teaching Aids PPT & BB FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Page 3 of 6 Sub. Code / Sub. Name: BT 6602 / Immunology (12 Hrs) Unit : III INFECTION AND IMMUNITY Unit Syllabus: INFECTION AND IMMUNITY Injury and inflammation. Immune responses to infections. Immunity to virus, bacteria, fungi and parasites. Cytokines, Complement, Immunosuppression and Tolerance. AIDS and Immunodeficiency Diseases. Resistance and immunization. Vaccines. Objective: To learn about infection and immune responses to an antigen, immunodeficiency and vaccines Session No * Topics to be covered Ref Teaching Aids 19 Injury and inflammation T2(327-346) PPT & BB 20 Immune responses to infections T2(258) PPT, Video & BB 21 Immunity to viruses and bacteria T2(447-470) PPT & BB 22 Immunity to fungi and parasites T2(447-470) PPT & BB 23 Cytokines T2(302-321) PPT, Video & BB 24 Complement T2(168-185) PPT, Video & BB 25 Immunosuppression and tolerance T2(402-416) PPT, Video & BB 26 Immunosuppression and tolerance T2(402-416) PPT, Video & BB 27 AIDS T2(493-518) PPT, Video & BB Immunodeficiencies T2(493-518) PPT & BB 28 Resistance and immunisation T2(476-480) PPT & BB 29 Vaccines. T2(475-488) PPT & BB 30 Content beyond syllabus covered (if any): Host defense mechanism and escape mechanism of microbes to immune responses * Session duration: 50 mins FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Page 4 of 6 Sub. Code / Sub. Name: BT 6602 / Immunology Unit : IV TRANSPLANTATION AND TUMOR IMMUNOLOGY (8 Hrs) Unit Syllabus: TRANSPLANTATION AND TUMOR IMMUNOLOGY Transplantation - Genetics of transplantation and Laws of transplantation. Tumor immunology, Tumor antigens, Tumor immune response, Tumor diagnosis and Tumor immunotherapy. Objective: To learn about Tumor immunology Session No * 31 32 33 34 35 Topics to be covered Ref Teaching Aids Introduction to transplantation T2(425-439) PPT, Video & BB Genetics of transplantation T2(440-443) PPT & BB Genetics of transplantation T2(440-443) PPT & BB Laws of transplantation T2(440-443) PPT, Video & BB Introduction to tumor immunology T1(374-395) T2(525-545) PPT, Video & BB Tumor immunology related to clinical aspects T1(374-395) T2(525-545) PPT & BB Tumor immunology T1(374-395) PPT & BB Review - - 36 37 38 Content beyond syllabus covered (if any): Apoptosis, Transgenic mice, Gene knock outs * Session duration: 50 mins FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Sub. Code / Sub. Name: BT 6602 / Immunology Unit : V ALLERGY, HYPERSENSITIVITY AND AUTOIMMUNITY Page 5 of 6 (7 Hrs) Unit Syllabus: ALLERGY, HYPERSENSITIVITY AND AUTOIMMUNITY Allergy and Hypersensitivity - Types of Hypersensitivity. Autoimmunity, Autoimmune Disorders and Diagnosis Objective: To learn Autoimmunity Session No * 39 40 41 42 43 44 45 Topics to be covered Introduction to autoimmunity Types of Hypersensitivity – Type I & II Ref T1( 396-420) T2(407- 416) T2(371-396), T1(322-347) Types of Hypersensitivity – Type III & IV T2(371-396), T1(322-347) Autoimmunity T1 420 Autoimmune disorders T1(421- 448) Autoimmune disorders and diagnosis T1(421- 448) Review - Teaching Aids PPT & BB PPT, Video & BB PPT, Video & BB PPT & BB PPT, Video & BB PPT & BB Content beyond syllabus covered (if any): Rheumatoid Arthritis, Myasthenia Gravis, Systemic Lupes. * Session duration: 50 mins - FT/GN/68/01/23.01.16 SRI VENKATESWARA COLLEGE OF ENGINEERING COURSE DELIVERY PLAN - THEORY Page 6 of 6 REFERENCES: TEXT BOOKS: 1.Roitt I, Male, Brostoff.” Immunology”, Mosby Publ., 12th edition, 2011. 2.Kuby J, “Immunology”, WH Freeman & Co., 7th Edition, 2012. 3.Ashim K. Chakravarthy, “Immunology”, Tata McGraw-Hill, 2006. REFERENCES: 1.Coico, Richard, “Immunology: A Short Course”, 7th Edition. John Wiley, 2015. 2.Khan, Fahim Halim, “Elements of Immunology”, Pearson Education, 2009. Prepared by Approved by Prof. R. B. Narayanan Prof. Dr. E.Nakkeeran PROFESSOR HEAD OF THE DEPARTMENT /BT 29.12.2016 29.12.2016 Signature Name Designation Date Remarks *: Remarks *: * If the same lesson plan is followed in the subsequent semester/year it should be mentioned and signed by the Faculty and the HOD