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Levels of Organization • How do unicellular and multicellular organisms differ? • How does cell differentiation lead to the organization within a multicellular organism? Levels of Organization • cell differentiation • stem cell • tissue • organ • organ system All living things are made up of cells…. • The cell is the smallest unit of a living thing. http://learn.genetics.utah.edu/content/begin/cells/scale/ If an organism is unicellular, all functions of life happen within that one cell. If an organism is multicellular, different cells have different jobs and they all work together. Unicellular Organisms • “uni-” = one • Prokaryotes are unicellular organisms • Some algae, some protists, and some eukaryotes (yeasts), are unicellular • Can still do everything they need to stay alive Multicellular Organisms Multicellular organisms are made of many types of eukaryotic cells working together, each with a specialized function. How do unicellular and multicellular organisms differ? Multicellular Organisms • “multi-” = more than one • Plants, animals, some protists, and most fungi are multicellular • Start as a single cell many cells cells differentiate (change) into different types of cells cells group together • Advantages- can grow larger and have specialized cells for different functions Link: http://www.teachersdomain.org/resource/tdc02.sci.life.stru.different/ Multicellular Organisms (cont.) • All cells in a multicellular organism come from one cell: a fertilized egg. • The process by which cells become different types of cells is called cell differentiation. Multicellular Organisms (cont.) Stem cells are unspecialized animal cells that are able to develop into many different cell types. fiber Science Use a long muscle cell Common Use a thread Why do we hear so much about stem cells & what are they? • The human body is composed of many different types of cells – e.g. muscle cells, skin cells, liver cells, cardiovascular cells, etc. • Not all cells have the same potential – Some cells remain “immature”—these are stem cells • When stem cells “mature,” or differentiate they turn into the different cells of the body (or somatic cells) • http://www.youtube.com/watch?v=tPulEAryPO0 Self-renew a stem cell can reproduce itself by cell division Differentiate a stem cell can specialize into a particular type of somatic cell Stem cells are multi-talented There are two main types of Stem Cells—Adult & Embryonic Stem Cells • Adult stem cells – found in adult tissue – can self-renew many times – are multipotent – they can differentiate to become only the types of cells in the tissue they come from. • hematopoietic stem cells – give rise to blood cells • mesenchymal stem cells – give rise to cells of connective tissues and bones • umbilical cord stem cells – a rich source of hematopoietic stem cells • stem cells found in amniotic fluid – might be more flexible than adult stem cells There are two main types of Stem Cells—Adult & Embryonic Stem Cells • Embryonic stem cells – come from embryos • This stage embryo is called a Blastocyst – ~5 days old, a hollow microscopic ball of cells – can self-renew forever; adult stem cells have a cell-division limit – are pluripotent – they can differentiate to become almost EVERY cell in the body – live in a Petri dish, not a woman's body Multicellular Organisms (cont.) • Plants have unspecialized cells similar to animal stem cells. • These cells are grouped in areas of a plant called meristems. Level 1 : Cells • Cells can be specialized (have a certain function) • The size and shape of a cell relates to its job or function. • Cells are made of different structures that perform different functions that keep a cell alive. Level 2: Tissues • Tissue = group of cells that work together to do a specific job • Ex: Heart muscle tissue is made of heart muscle cells • Animals have 4 types of tissue: nerve, muscle, connective, protective • Plants have 3 types of tissue : transport, protective, ground Level 3: Organs • Organ = structure that is made up of 2 or more tissues working together to get a specific job done • Ex: Stomach – muscle tissue moves food, special tissues make chemicals to digest food, connective tissue holds stomach together, nervous tissue sends messages back and forth between the stomach and brain Level 4: Organ Systems • Organ system = group of organs working together to perform a specific function • Each organ system has a specific job • Ex: Digestive system is made of several organs including the stomach and intestines Levels of Organization • Cells • Tissues • Organs • Organ Systems • Organism Cells Tissues Organs Organ Organism Systems Multicellular Organisms (cont.) Multicellular organisms usually have many organ systems that work together to carry out all the jobs needed for the survival of the organism. How does cell differentiation lead to the organization within a multicellular organism? • A unicellular organism carries out all the activities necessary for survival within one cell. • Cells become specialized in structure and function during cell differentiation.