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CAST OF CHARACTERS: WHITE BLOOD CELLS Leukocytes: colorless blood cells that protect the body against invading bacteria, viruses, or other foreign cells Granulocytes: Leukocytes that contain granules (sacs) filled with potent chemicals neutrophil: uses its prepackaged chemicals to degrade any microbe it ingests eosinophil: “degranulate” – release their chemicals to work on cells or microbes in their surroundings basophil: Agranulocytes: leukocytes that lack visible cytoplasmic granules Lymphocyte: arises from bone marrow and becomes functionally mature in the lymphoid organs of the body - large #’s of them are found in the body but only a small number in the blood stream - They are firmly emeshed in the lymphoid tissue -Two kinds 1. T cells - act directly against virus-infected cells and tumor cells - mature in the thymus - give cell-mediated immunity -3 types: helper T cells – essential for activating B cells and other T cells as well as natural killer cells and macrophages cytotoxic (killer) cells – rid body of cells that have been infected by viruses and by cancer cells, and responsible for rejection of tissue and organ grafts suppressor T cells – brings an end to the immune responses no longer needed 2. B cells - give rise to plasma cells, which produce antibodies that are released to the blood - grow independent of the thymus - humoral immunity Monocytes: once in tissues, monocytes differentiate into highly mobile macrophages “big eaters” *Phagocytes: large white blood cells that can engulf and digest microorganisms and other antigenic particles – “Cell eaters”