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Transcript
B. Montgomery Pettitt is the Hugh Roy and Lillie Cranz Cullen Professor of Chemistry and
Professor of Physics, Computer Science, Biology and Biochemistry at The University of
Houston. He earned his B.S. and Ph.D. from the University of Houston, was a Postdoctoral
Fellow at the University of Texas at Austin and an NIH Fellow at Harvard University. His
research ranges from modeling the behavior of liquids to work aimed at elucidating the nature of
biomolecules tethered to high tech chip sensors. Using biological molecules tethered to chips
creates technology for medical diagnosis, drug discovery and even computing. Yet, the
fundamental problem is the lack of theories capable of making accurate predictions to be used
in device design. His theoretical research interests led to the development of methods for
calculating binding constants, phase behavior, internal conformational structure and equilibria of
biopolymers near surfaces and in aqueous solution. Conformational stability studies rely on the
development of advanced theoretical and simulation methods that are applied to
multicomponent solutions as well as fundamental work on the nature of the hydrophobic effect
and wetting of surfaces. Other specific recent research interests include understanding the
structure of proteins and nucleic acids in solution and on surfaces, predicting the
thermodynamics of solutions, including water, ions, polar biomolecular solutes and other
condensed phase systems via theoretical methods and development of methods to compare
and search genomes and other complex systems of information.