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Genome is...
... the complete set of
genetic information
contained within all of
the chromosomes of an
organism. It defines the
particular phenotype
of an individual.
What is Genomics?
The study of the
complete genetic material
of an organism. In other
words, it is the study
of genomes. Genomics
should not be confused
with genetics, which
is the study of single
genes and their potential
effects. Genomics refers
to all of the genetic
material of an organism,
that is, determining the
entire sequence of DNA,
including all genes but
also non-coding regions.
Leader in Genomic Medicine in Latin America
T
he National Institute of Genomic Medicine (INMEGEN) was
established in 2004 by the Promotional Consortium of the National
Institute of Genomic Medicine. The consortium, created in 2001, was
comprised by the National Autonomous University of Mexico, the National
Council for Science and Technology, the Ministry of Health and the Mexican
Health Foundation.
Today, INMEGEN is the national leader in genomic research for medical
applications seeking to improve health in Mexico. Its main objectives are:
developing scientific research projects with cutting edge technology, training
human resources of excellence; and generating genomic innovations and
applications to improve health care in compliance with universal ethical principles
and respect for human rights.
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Genome
Genome is the entire genetic
information of any living organism.
This information is found in the
chromosomes of an organism’s cells
and is composed of deoxyribonucleic
acid (DNA). This contains the
hereditary units, called genes, which
are responsible for encoding the
characteristics of cells and organisms.
Genomics
Genomics is the study of genes and
their biologicial function. It aims at
understanding gene structure, gene
expression and interpretation of
gene-gene interaction. Genomics
has revolutionized the Biological
Sciences of the 21st century.
Genomic Medicine
Is the application of genome discoveries
to human health and disease. Its main
goal is to translate this knowledge
into clinical and preventive medicine.
Genomics, which was born out
of the deciphering of the human
genome, is applied to health in what
is known as Genomic Medicine.
This new branch of medicine aims
at understanding quantitatively
and qualitatively the genomic,
transcriptomic, metabolomic
and proteomic contributions
to human disease and their
relationship to environment.
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What is Genomic
Medicine?
Medical practice based
on genomic knowledge
aimed to produce a more
predictive, preventive,
participative and
personalized medicine.
Leader in Genomic Medicine in Latin America
Why is Genomic Medicine important?
What is INMEGEN?
The National Institute
of Genomic Medicine
(INMEGEN) is a National
Health Institute, leader
in genomic research
applied to improve
health in Mexico.
Human genome variation can be associated
to health and disease. The identification of
such changes is fundamental to understand, to
treat and also to be able to prevent common
diseases such as diabetes, obesity, hypertension
or cancer. Genomic medicine studies human
susceptibility to disease and treatment.
Genomic medicine is also closely related to
other genomic sciences. Nutrigenomics for
example, identifies the effect of diet on gene
expression, with the purpose of designing
diets based on a specific population genetic
profile. Another example of population specific
research is Pharmacogenomics that aims at
studying drugs and their effect on humans at a
molecular level. This research, will soon allow us
to have, not only target specific drugs that are
effective, but also with minimum side effects.
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The primary role
of INMEGEN is the
development of
research on Genomic
Medicine in Mexico.
Structure of INMEGEN
INMEGEN is integrated by four main
areas: Research, Education and Outreach,
Technological Development and Entailment and
Institutional Development; each with strategic
objectives that, as a whole, allow INMEGEN to
maintain an undisputed leadership in Mexico.
Current fundamental challenges are:
1. The generation of knowledge
2. Education
3. Strategic alliances that integrate the
healthcare system in México
4. Access to cutting-edge technology
5. Innovation promotion
6. Open communication with society
We promote and implement education
programs specialized in Genomic
Medicine and all its related sciences.
Research
Collaboration with clinicians facilitates the
development of research projects that will provide
the base for future medical practice in Mexico.
Understanding the population structure and the
epidemiologic characteristics is fundamental
for research in Genomic Medicine. Research
areas are influenced by worldwide scientific
development and available human resources.
Lines of Research
Genomics of metabolic diseases
Oncogenomics
Functional genomics of cancer
Nutrigenetics and nutrigenomics
Genomics of autoimmune and atopic diseases
Genomics of cardiovascular disease
Proteomics and protein structure
Molecular bases of chronic liver diseases
Pharmacogenomics
Population genomics
Ethical, legal and social implications of genomics
Computational genomics and expression analysis
Genomics of bone metabolism
Genomics of cellular response to oxidative stress
Genomics and infectious diseases
Epigenomics
Genomics of premature delivery
Genomics of psychiatric and neurological disease
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Leader in Genomic Medicine in Latin America
INMEGEN has nurtured
a comprehensive
education program
containing a portfolio
of activities directed
toward teaching genome
medicine at all levels.
The Office of Education
has taken the next step
to get involved with the
Institute’s commitment
to excellence in
science, technology and
academic training.
Education and Outreach
This area is devoted to highly specialized
training in Genomic Medicine. It offers pre and
post graduate courses, academic exchange,
continuing education programs and online
courses. It is responsible for diseminating
scientific information to the Mexican community
through the Institute’s web site and other
digital media. It also coordinates and regulates
INMEGEN’s specialized digital library.
We promote and
implement education
programs specialized in
Genomic Medicine, thus
contributing to train
professionals capable of
assimilating and applying
this new knowledge.
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Technological Development
Genomic research is characterized by the
management and analysis of the massive
amounts of data generated by cuttingedge genome technologies. Therefore,
there is a constant demand for best
practices involving services in highperformance computing, networking,
and storage. The sustainability and
scalability of information technology
(IT) infrastructure are vital to support
INMEGEN´s science research and its
translation to genomic medicine.
For the first time in Latin America,
products and equipment from leading
companies around the world are put
together into four High Technology
Units at INMEGEN. These offer
researchers a broad range of options for
genome analysis and high throughput
molecular profiling technologies such as
Next-Generation Sequencing (NGS).
INMEGEN is continuously
adapting to increasingly
complex research with state of
the art technology. The well
established and broad training
program provides its trainees
with advances in genomic
innovations in compliance
with ethical principles and
respect for human rights.
By using genomic
information we can
select the optimal
therapeutic strategy for
each individual within
a specific population.
We innovate molecular
diagnostics for the
Mexican population.
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Leader in Genomic Medicine in Latin America
We establish mechanisms
that assure compliance
with an ethical, legal and
social framework within the
realm of the development
of Genomic Medicine.
Entailment and Institutional Development
Genomic medicine plays a central role in current
healthcare. It has become an important part of
diagnosis, prognosis, and treatment in clinical
practice. It is therefore essential to include
new discoveries as they develop in education
and medical practice. INMEGEN maintains
strategic alliances with other public and private
institutes of health in Mexico and around the
world. People at INMEGEN foster an innovative
environment fundamental for the generation
of services and products that will serve public
health. Projects at INMEGEN follow strategic
planning, establishing and formalizing legal
actions for all of the institute’s activities.
Services
INMEGEN is the Genomic Medicine reference
center in Mexico. It offers a variety of services
not only to the healthcare sector but also to
academic and other non-academic organizations.
Services include molecular diagnosis such
as paternity tests, pharmacogenomic tests
and monitor hematopoietic cell transplant,
to mention just a few. Genome research
technology services include gene expression,
genotyping, next generation sequencing, protein
identification, histology and microscopy services.
A variety of other projects in the areas of
nutrigenomics, pharmacogenomics, cytogenetics
and epigenetics can also be proposed.
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Healthcare and wellness
decisions will soon include
a genomic component.
INMEGEN has taken the first
steps leading the analysis
of genomic diversity of the
Mexican population. This
research will be translated
into medical applications to
improve healthcare in Mexico
with an important impact
on costs for public health.
INMEGEN offers continuing and online education,
scientific advice and management consulting for
technological development and innovation.
In order to support research, INMEGEN
provides specialized bibliographic
services through its digital library.
Learn more about INMEGEN and its
services at www.inmegen.gob.mx
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Leader in Genomic Medicine in Latin America
The library and e-library at
INMEGEN aim at disseminating
reliable information about
discoveries, trends and
advances in Genomic
Medicine to the scientific
community. Our website is
designed to provide insights
of INMEGEN´s research and
education to the society.
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Contact Us
General Director
[email protected]
phone: +52 (55)53501900
Ext. 1901
Research
[email protected]
phone: +52 (55) 53501900
Ext. 1910
Education Programs and Outreach
[email protected]
phone: +52 (55) 5350-1900
Ext. 1121
Entailment and Institutional
Development
[email protected]
phone: +52 (55) 53501900
Ext. 1916
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Digital Library
[email protected]
phone: +52 (55) 53501933
Social Communication and Press
[email protected]
phone: +52 (55)53501900
Ext. 1136
Courses
[email protected]
phone: +52 (55)53501900
Ext. 1113
Internships
[email protected]
phone: +52 (55) 53501900
Ext. 1122
Leader in Genomic Medicine in Latin America
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