Download Comprehensive Genomic Profiling Opens Up More

Comprehensive Genomic Profiling Opens
Up More Treatment Possibilities For Your Patients
FoundationOne® and FoundationOne® Heme are pan-cancer comprehensive genomic profiles that identify all classes of genomic
alterations (base substitutions, copy number alterations, insertions/deletions, and gene rearrangements) in a patient’s cancer and match
them with relevant targeted therapies and clinical trials based on the latest scientific and clinical data. This unique genomic profile based
on an individual patient’s molecular drivers enables more personalized healthcare solutions to optimize treatment outcomes.
Comprehensive and Trusted
Conserve Tissue and Save Time
• Identifies all classes of genomic alterations with >99% specificity, with
validation published in a peer-reviewed journal.1
• Identifies 3X more targeted therapy options than traditional standard
of care tests and hotspot panels.1
• Requires only a small amount of tissue including routine biopsy samples
and FNA specimens.
• Can be performed on low purity samples.
Informative, Relevant and Actionable Results
• All clinically relevant alterations identified are matched to targeted
therapies and clinical trials based on current scientific evidence and
published clinical data.
• Report is powered by 20+ bioinformaticians and genomic scientists
combined with state-of-the-art algorithms to report the most clinically
relevant information for a patient.
More Than Just a Test
FoundationACCESS support services help patients and providers with:
• Reimbursement and financial assistance for FoundationOne testing.
• Comprehensive case management when reimbursement issues create
obstacles to off label or investigational therapies.
• Clinical trials navigation for patients.
1 Frampton GM, Fichtenholtz A, Otto GA, et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol.
2013 Nov;31(11):1023-31. PubMed PMID: 24142
For Solid Tumors
For Hematologic Malignancies And Sarcomas
Sequences the entire coding region
of 315 cancer-related genes plus select
introns from 28 genes
Sequences the entire coding region of 405
cancer-related genes and the RNA of 265 genes
commonly rearranged in cancer
Comprehensive Genomic Profiling
Rearrangements
Base
substitutions
Insertions and deletions
Copy number
alterations