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Bioinformatic and Computational research in Biological Sciences Jason Bond Les Goertzen Rita Graze Ken Halanych Mark Liles Scott Santos Not just Dept. of Biological Science connections to several AU units and national & international colleagues Genomic Revolution • Very large volumes of data • Computationally expensive analyses Genomic Revolution Microbes to Vertebrates Genomic Revolution Phylogenomics – Genomic computation – Tree building Bond 2014 Current Biology Populations to species to major lineages of life Bioinformatics Pipeline Pleurobrachia Genome 160Mb genome 600x coverage Moroz et al. Nature 2014 Gene Networks & Interactions Proteomics This compound-protein-protein interaction network shows the interactions of 1.160 compounds and 894 proteins. Ecological Analyses Post Gulf oil spill analyses of small animal communities. Brannock et al. 2014 Dream hires • Jonathon Eisen, UC Davis • Steven Salzberg, Johns Hopkins • Brian Haas, Broad Institute • Thomas Juenger, Univ. Texas • Matthew Hahn, Indiana Univ.
