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Feedback Loops Endocrinologist: _________________________________ Use the completed feedback mechanism to answer the questions below. a. What action does hormone 1 have on the anterior pituitary? b. What action does hormone 2 have on the hypothalamus? c. What action(s) does hormone 3 have? d. Is this an example of positive feedback or negative feedback? e. Explain a benefit of the body utilizing three organs or glands to trigger a response. a. What would happen to a person who ingested a dairy rich meal? b. What would happen to a person who suffered from hypothyrodism (an underactive thyroid)?*Assume the parathyroid activity is normal. c. What would happen to a person who took Boniva (ibandronate sodium)? Boniva is a nitrogen containing bisphosphate that inhibits osteoclast-mediated bone resorption. d. What would happen to a person who was prescribed Miacalcin? Miacalcin is a calcitonin nasal spray. e. Male deer grow impressive antlers to attract females. Male deer lose their antlers after the breeding season but before the females give birth. What is the evolutionary significance of the male antlers and the timing of antler loss? f. What is happening to a pregnant woman? How would the baby influence her calcium feedback mechanism? g. Explain why a doctor always suggests a calcium supplement to his or her patients? a. What happens after a person eats a carbohydrate rich meal? b. Where is glucose stored in the body? c. What happens if the blood glucose level is too low? d. What would happen to a person's blood sugar if they cannot produce or respond to insulin? e. What would happen to a person's stored sugar if they cannot produce or respond to insulin? f. If someone does not respond to insulin what can they do to ensure that their blood sugar does not get too high? g. If someone does not produce insulin what can they do to ensure that their blood sugar does not get too high? h. Think evolutionarily, why does your body work to store sugar at the potential determent to your health? a. What happens when the hypothalamus releases GnRH? b. What would happen if a man's pituitary gland could not produce FSH and/or LH? c. When there are normal to high levels of androgen in the blood what message or signal is sent to the hypothalamus? d. If someone injected or absorbed additional androgens what would we see in the body (not the hypothalamus)? e. If someone injected or absorbed additional androgens what would we see in the hypothalamus? f. Describe the levels of FSH and LH in the blood if the testes could not produce androgens. a. What does low blood oxygen trigger? b. Why does low blood oxygen cause the reaction it does? c. What happens when the oxygen carrying capacity increases? d. Is this an example of positive feedback or negative feedback? Why? e. Why do some athletes train in higher altitudes? f. What would happen to someone who had liver or kidney cancer? (The liver or kidney cannot perform their functions as well.) g. What would happen if someone did not have a sufficient amount of red marrow? Why? h. What would happen if someone increased the amount of erythropoietin in their body? i. What are the advantages of increasing the amount of erythropoietin in a person's body? j. What are the disadvantages of increasing the amount of erythropoietin in a person's body?