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Honors Biology Syllabus And Curriculum Guide (last edited )2013 Syllabus / Pacing Guide page 2 Introduction Unit page 3 - 4 Chemistry page 4 - 5 Biochemistry page 5 - 6 Cell Biology and Transport page 6 - 7 Photosynthesis and Cellular Respiration page 7 - 8 Cell Division page 8 - 9 Protein Synthesis page 9 - 10 Genetics page 10 - 12 Evolution page 12 - 13 Taxonomy page 13 - 14 Plants page 14 - 15 Animals page 15 - 16 Ecology page 16 - 17 Anatomy page 17 - 19 Additional Notes page 19 1 Subject Matching SOL (Note: Bio.1 matches for all units) Bio.1b,c,k Bio.4b Time Allowed Labs 4 days Chemistry Bio.2a 5 days Biochemistry Bio.2b,c 9 days Cell Biology and Transport Bio.3a-e 8 days Photosynthesis and Cellular Respiration Cell Division Bio.2d 5 days -Scientific Process and Experimental Design (SLP) -Safety and the Material Safety Data Sheet (SLP) -Current Applications in Science (SLP) -pH lab -The Physical and Chemical Properties of Water (SLP) -Macromolecule Identification Lab -Polysaccharide (cracker) Lab -Macromolecules (SLP) -The Effects of Heat and Acid on Enzyme Catalase (SLP) -“e” Lab -Cell Biology Lab -Cell Parts (SLP) -Prokaryotes (SLP) -The Ratio of Surface Area to Volume (SLP) -Structure and Function of Cell Membranes (SLP) -Energy and ATP (SLP) Bio.5a-c 4 days Protein Synthesis Bio.5e-j 5 days Genetics Bio.5d,f,i,j 12 days Evolution Bio.6a-e Bio.7a-e Bio.4a-f Bio.6e 5 days Plants Bio.4a-c 4 days Animals Bio.4a-d 6 days Ecology Anatomy Bio.8a-e Bio.4b,d-f 3 days 13 days Introduction Unit Taxonomy 5 days -Onion Mitosis Lab -Mitosis Video Lab -Pop Bead Lab -The Cell Cycle and Mitosis (SLP) -Meiosis (SLP) -Strawberry DNA Extraction -DNA Structure, Nucleic Acids, and Proteins (SLP) -Genetic Corn Lab -Make-a-Kid Lab -Pedigree Lab -Electrophoresis Lab -Genetics Disease Paper -Genetic Variation and Mutations (SLP) -Mendelian Genetics (SLP) -Biotechnological Issues and Bioethics (SLP) -Hardy-Weinberg Lab -Adaptation and Evolution (SLP) -Fungi Observation -“Classify This” Lab -The Germ Theory and Koch’s Postulates (SLP) -Flower Comparison Lab -Plant Group Identification Lab -A Dichotomous Key of Virginia’s Native Plants (SLP) -Animal Group Identification Lab -Booklet or Presentation -Succession (SLP) -Fetal Pig Dissection -EKG Lab -Bone Identification Lab -Heart/Kidney/Eye Dissection -Body Systems (SLP) 2 1. Introduction Unit – 4 days A. Concepts / SOL The student will know, or be able to do the following. - The scientific research method. - The difference between a fact, hypothesis, law, and theory. - All the characteristics of living things. - The levels of organization. - Hypothesis are formulated based on direct observations from scientific literature (Bio.1b) - Variables are defined and investigations are designed to test the hypotheses (Bio.1c) - Differentiation is made between a scientific hypothesis, theory and law (Bio.1k) - Maintenance of homeostasis (Bio.4b) B. Vocabulary - science observation hypothesis experiment data conclusion control law theory metabolism homeostasis adaptation organelles cell tissue organ organism population community ecosystem biosphere biotic abiotic C. Laboratory Exercises - Scientific Process and Experimental Design (SLP) 3 - Safety and Material Safety Data Sheet (SLP) Current Applications in Science (SLP) 2. Chemistry – 5 days A. Concepts / SOL The student will know, or be able to do the following. - The difference between a solid, liquid, gas, and plasma. - The three subatomic particles. - The difference between an atom and an element. - The difference between a compound and a mixture - How to use the periodic table. - How to draw atoms using the Lewis dot and electron shell methods. - The difference between ionic, covalent, and hydrogen bonding. - What an isotope is. - Water chemistry and its impact on life processes. (Bio.2a) - What the pH scale is and how to use it. - The actual H+ and OH- concentrations of items. B. Vocabulary - chemistry matter solid liquid gas plasma atom proton neutron electron element atomic number atomic mass Noble gas subatomic particle compound mixture chemical change physical change valence electrons Lewis dot structures periodic table bonding - covalent bond ionic bond cation anion hydrogen bond polar covalent cohesion surface tension density solvent solute solution isotope radio isotope deuterium tritium pH scale acid base neutral hydronium ion hydroxide io 4 C. Laboratory Exercises - Determine the pH of common substances and then determine the concentration of hydronium and hydroxide ions present. The Physical and Chemical Properties of Water (SLP) 3. Biochemistry – 9 days A. Concepts / SOL The student will know, or be able to do the following. - The structure and function of macromolecules. (Bio2.b) - How to draw molecules using the stick method. - Basic functional groups and their properties. - How polymers and made and broken down. - The properties of carbohydrates, proteins, lipids, and nucleic acids and how to draw them. - The nature of enzymes. (Bio.2c) B. Vocabulary - organic compound hydrocarbons isomers functional group hydroxyl carbonyl carboxyl amino phosphate methyl monomer polymer dehydration synthesis hydrolysis carbohydrate monosaccharide glucose (alpha and beta) fructose galactose disaccharide lactose maltose sucrose - - high fructose corn syrup polysaccharide starch glycogen cellulose fiber diabetes insulin protein amino acid variable group peptide bond polypeptide primary, secondary, tertiary, quaternary structure denature enzyme substrate lipid hydrophobic hydrophilic fat 5 - triglyceride unsaturated saturated phospholipid wax steroid - hormone cholesterol nucleic acid deoxyribonucleic acid ribonucleic acid C. Laboratory Exercises - - Use benedicts solution, iodine solution, and biurete solution to determine whether or not a substances contain monosaccharides, starches, or proteins. Chew a cracker to see if salivary enzymes break down the starches. Macromolecules (SLP) The Effects of Heat and Acid on the Enzyme Catalase (SLP) 4. Cell Biology and Transportation – 8 days A. Concepts / SOL The student will know, or be able to do the following. - Evidence supporting the cell theory (Bio.3a) - Characteristics of eukaryotic and prokaryotic cells (Bio.3b) - Similarities between the activities of the organelles in a single cell and a whole organism (Bio.3c) - The cell membrane model (Bio.3d) - The impact of surface to volume ratio on cell division, material transport, and other life processes (Bio.3e) - Compare and contrast plant and animal cells. - Identify the structure and function of organelles. - Tell why cells stay so small. - The parts of a microscope and how they function. - The role diffusion and osmosis play in a cell’s life. B. Vocabulary - Hooke Leeuvenhoek Schleiden Schwann Virchow Cell Theory surface area to volume ratio eukaryotic - prokaryotic cytoplasm ribosome endoplasmic reticulum (rough and smooth) golgi apparatus mitochondria cristae cellular respiration 6 - matrix lysosome apoptosis cilia 9+2 arrangement flagella microtubules nucleus nucleolus nuclear envelope cell membrane phospholipid bilayer channel, carrier, receptor, recognition proteins cell wall vacuole contractile vacuole turgor pressure plastid photosynthesis proplastid, chloroplast, leucoplast, amyloplast, chromoplast - - chlorophyll ocular lens, body, arm, nosepiece, objective lenses, stage, stage clips, diaphragm, base, light, fine focus, coarse focus magnification resolution Brownian motion passive transport active transport diffusion osmosis isotonic, hypertonic, hypotonic equalibrium plasmolysis cytolysis endocytosis exocytosis C. Laboratory Exercises - Basic “e” lab where students become familiar with the use of the microscope by observing how the position of the letter e changes. Cell biology lab where students observe 9 different items and compare the types of cells they see. Cell Parts (SLP) Prokaryotes (SLP) The Ratio of Surface Area to Volume (SLP) Structure and Function of Cell Membranes (SLP) 5. Photosynthesis and Cellular Respiration – 5 days A. Concepts / SOL The student will know, or be able to do the following. - Describe the differences between ATP and ADP. - Describe the differences between autotrophs and primary and secondary heterotrophs. - Explain phosphorylation. 7 - The basic products and reactants of photosynthesis and cellular respiration. Explain the difference between an endergonic and exergonic reaction. Describe the parts of a chloroplast. Describe the light and dark reactions in detail. Explain the differences between a C3, C4, and CAM plant. Explain what an aerobic and anaerobic reaction are. Describe, in detail, the parts of glycolysis, krebs cycle, and fermentation. Explain the differences between chemeosmotic and substrate level phosphorylation. The capture, storage, transformation, and flow of energy through the processes of photosynthesis and respiration. (Bio.2d) B. Vocabulary - photosynthesis - cellular respiration - endergonic - exergonic - ATP - ADP - phosphorylation - ATPase - ATPsynthase - stroma - thylakoid membrane - grana - lumen - carotene - xanthophylls - accessory pigments - light dependent reaction - light independent reaction (Calvin Cycle) - chemeosmotic phosphorylation - NADPH - C3, C4, CAM - photorespiration - stomata - aerobic - anaerobic - cristae - matrix - fermentation - glycolysis - Krebs cycle (all acids) - facultative anaerobe - strict anaerobe - substrate level phosphorylation - lactic acid - ethanol C. Laboratory Experiences - Energy and ATP (SLP) 6. Cell Division – 4 days A. Concepts / SOL The student will know, or be able to do the following. - The make-up of a chromosome. 8 - The differences between somatic cells and gametes. The difference between the terms haploid and diploid. The concept of cell growth and division (Bio.5a) The concept of gamete formation. (Bio.5b) The concept of cell specialization. (Bio.5c) How crossing over increases genetic diversity. The differences between spermatogenesis and oogenesis. B. Vocabulary - chromosome chromotid centromere haploid diploid somatic cell gamete gene cell cycle interphase G1, S, G2 replicate mitosis - centrioles spindle fibers asters kinetichore prophase, metaphase, anaphase, telophase cytokinesis homologous pairs, tetrads crossing over ootid sperm polar bodies C. Laboratory Experiences - Observe mitosis as it has taken place in onion root tip cells. Have students observe video of mitosis actually taking place. Use “Pop Beads” to have students mimic the phases of cell division and meiosis. The Cell Cycle and Mitosis (SLP) Meiosis (SLP) 7. Protein Synthesis – 5 days A. Concepts / SOL The student will know, or be able to do the following. - The difference between DNA and RNA. - Historical development of the structural model of DNA (Bio.5e) - How the processes of replication, transcription, and translation occur. - How a gene is used to make a protein. - Genetic variation (Bio.5f) - Structure, function and replication of nucleic acids (Bio.5g) - Events involved in the construction of proteins (Bio.5h) 9 - Use, limitations, and misuse of genetic information (Bio.5i) Exploration of the impact of DNA technologies (Bio.5j) B. Vocabulary - DNA RNA Deoxyribose Ribose Phosphate Group Nitrogen Base Nucleotide Adenine Guanine Thymine Cytosine Uracil Purine Pyrimidine Hydrogen Bonds Double Helix Griffith Chargraff Pauling Franklin and Wilkins Watson and Crick Replication - DNA helicase DNA polymerase Transcription DNA ligase RNA polymerase Translation TRNA, mRNA, rRNA Amino Acid Ribosome Codon Anti-codon Peptide Bond Protein Gene Base Pair Protein Synthesis Sense Mis-sense 3’ – 5’ P and A site Promotor Terminator C. Laboratory Experiences - Extract the DNA from strawberries. DNA Structure, Nucleic Acids, and Proteins (SLP) 8. Genetics – 12 days A. Concepts / SOL The student will know, or be able to do the following. - Explain Mendel’s basic experiment and hypotheses. - The difference between genotype and phenotype. - Do a monohybrid and dihybrid Punnett Square. - The difference between codominance and incomplete dominance. - The different types of mutations. - The different sex chromosome mutations. 10 - Understand sex linked traits. How to use a pedigree. What causes a mutation. The blood types and Rh factor. The different types of twins. Do a Chi square problem. Understand how gel electrophoresis works and understand how to interpret the data derived from it. Predict inheritance of traits based on the Mendelian laws of heredity. (Bio.5d) Genetic variation (Bio.5f) The use, limitations, and misuse of genetic information. (Bio.5i) Explore the impact of DNA technologies. (Bio.5j) B. Vocabulary - Allele Heterozygous Homozygous Recessive Dominant Mendel Phenotype Genotype Heredity Pure-bred Mutation Gene Mutation Chromosome Mutation Autosome Sex Chromosome Nondisjunction Sex-linked Trait Pedigree Gel Electrophoresis - Monohybrid Cross Dihybrid Cross Punnett Squre Codominance Incomplete Dominance Karyotype Klinefelders Syndrome Turners Syndrome Ionizing Radiation Ultraviolet Radiation Rhesus Factor Antigen Antibody Fraternal Twins Identical Twins Chi Square Cloning C. Laboratory Experiences - Use specially bred corn to count genetic ratios and perform Chi Square activities. Use pennies to represent traits in the Make – A – Kid lab. Use the information learned in class to create a Genetic Disease Research Paper Trace a trait through a family history in the pedigree lab. 11 - Analyze data found at a crime scene using gel electrophoresis to determine who committed the crime. Genetic Variation and Mutation (SLP) Mendelian Genetics (SLP) Biotechnological Issues and Bioethics (SLP) 9. Evolution – 5 days A. Concepts / SOL The student will know, or be able to do the following. - Understand the Hardy-Weinberg Principle and how it can be used on populations. - Understand the hypotheses on the origins of life. - Explain Kettlewell’s observations and how they are a good example of microevolution. - The ideas of scientists whose works helped develop the theory of evolution. - Understand Darwin’s basic principles of evolution. - Explain the evidence supporting evolution. - Describe the types of natural selection, types of evolution, and the hypotheses on how evolution occurs. - Understand what a gene pool is and how to change it. - Structural similarities among organisms (Bio.6a) - Fossil record interpretation (Bio.6b) - Comparison of developmental stages of different organisms (Bio.6c) - Examine biochemical and structural similarities of different organisms. (Bio.6d) - Systems of classification that are adaptable to new scientific discoveries (Bio.6e) - Evidence found in fossil records (Bio.7a) - How genetic variation, reproductive strategies, and environmental pressures impact the survival of populations (Bio.7b) - How natural selection leads to adaptation (Bio.7c) - Emergence of a new species (Bio.7d) - Scientific evidence and explanations for biological evolution (Bio.7e) B. Vocabulary - Hardy-Weinberg Principle Redi Oparin Miller Microevolution - Gene Pool Kettlewell Genetic Drift Gene Flow Mutation Non-random Mating 12 - Natural Selection Aristotle Cuvier Lamarck Adaptive Radiation Malthus Natural Selection “On the Origin of Species” Biogeography Taxonomy Homologous Structures Vestigial Organs Comparative Embryology Molecular Biology - Stabilizing Selection Directional Selection Diversifying Selection Convergent Evolution Divergent Evolution Gradualism Punctuated Equalibrium Geographical Isolation Ecological Isolation Temporal Isolation Behavioral Isolation Mechanical Isolation Reproductive Failure Macroevolution C. Laboratory Experiences - Use playing cards to represent alleles and determine the characteristics of a population using the Hardy-Weinberg principle. Adaptation and Evolution (SLP) 10. Taxonomy (Viruses, Monera, Protista, Fungi) – 5 days A. Concepts / SOL The student will know, or be able to do the following. - List the 7 levels of classification. - List the 6 kingdoms and 3 domains and give example of each. - How viruses, monerans, protests, and fungi are classified and give examples of each classification group. - The “life” cycle of a virus. - How to write a name scientifically. - Understand the complex job of a taxonomist and the tools they use to classify living organisms. - Comparison of their metabolic activities (Bio.4a) - Maintenance of homeostasis (Bio.4b) - How the structures and functions vary among and within the eukarya kingdoms of protists, fungi, plants, and animals including humans (Bio.4c) - Human health issues, human anatomy, and body systems (Bio.4d) - How viruses compare with organisms (Bio.4e) - Evidence supporting the germ theory of infectious disease (Bio.4f) - Systems of classification that are adaptable to new scientific discoveries (Bio.6e) 13 B. Vocabulary - Taxonomy Aristotle Linnaeus Whittaker Binomial Nomenclature Retrovirus Lytic Cycle Lysenogenic Cycle Reverse Transcriptase Endospore Saprophytic Photoautotroph Chemeautotroph Strict Anaerobe Facultative Anaerobe Pathogenic Cocci Bacilli Spirilli Sarcodina Ciliophora - Zoomastigophora Sporozoa Giardia Plasmodium Paramecium Trypanosoma Pseudopodia Flagella / Cilia Mycelium Hyphae Chitin Zygomycota Spore Basidiomycota Ascomycota Deuteromycota Sporangia Lichens Endosymbiosis Systematics Phylogeny C. Laboratory Experiences - Observe parts of a fungi reproductive body. Allow students to become taxonomists by classifying random objects. The Germ Theory and Koch’s Postulates (SLP) Viruses (SLP) 11. Plants – 4 days A. Concepts / SOL The student will know, or be able to do the following. - Comparison of their metabolic activities (Bio.4a) - Maintenance of homeostasis (Bio.4b) - How the structures and functions vary among and within the eukarya kingdoms of protists, fungi, plants, and animals including humans (Bio.4c) - The 4 different types of plant tissues. - The parts of a flower and seed. - The benefits of fruit and how flowers have coevolved with pollinators. B. Vocabulary 14 - Meristematic Tissue Apical Meristem Lateral Meristem Dermal Tissue Ground Tissue Collenchyma Parenchyma Sclerenchyma Vascular Tissue Xylem Phloem Bryophyta Pioneer Species Pterophyta Rhizome Fiddleheads Sori Gymnosperm Seeds Angiosperm Flower - Fruit Herbaceous Woody Dicotyledon Net Veins Monocotyledon Parallel Veins Petals Sepals Stamen Pistil Stigma Style Filament Anther Nectar Pollen Endosperm Coleoptile Carpel C. Laboratory Experiences - Look at different flower and compare the reproductive parts of the flowers. Students will walk around the school and identify different types of plants. A Dichotomous Key of Virginia’s Native Plants (SLP) 12. Animals – 6 days A. Concepts / SOL The student will know, or be able to do the following. - Comparison of their metabolic activities (Bio.4a) - Maintenance of homeostasis (Bio.4b) - How the structures and functions vary among and within the eukarya kingdoms of protists, fungi, plants, and animals including humans (Bio.4c) - Human health issues, human anatomy, and body systems (Bio.4d) - The three cell layers, three body plans, and three types of symmetry. B. Vocabulary - porifera - pores 15 - spicules budding cnideria polyp medusa tentacles cnidocytes platyhelminthes ganglia parasite cysts hermaphroditic anelidia hydrostatic skeleton oligochaetes polychaetes leeches segmentation mollusca mantle foot radula gastropods bivalves cephalopods arthropoda exoskeleton chitin head abdomen thorax insects arachnids myriapods - crustaceans nematoda trichinella echinodermata endoskeleton larvae water vascular system chordata notochord pharyngeal gill slits post-anal tail endoskeleton agnatha jawless chondrichthyes cartilage osteichthyes bone swim bladder amphibia ectothermic reptiles scales amniote egg three chambered heart aves feathers endothermic mammalia mammary glands monotremes hair marsupial placental C. Laboratory Experiences - Classify preserved specimen into different phyla and classes. Prepare a booklet / presentation of the data on animals. 13. Ecology – 3 days A. Concepts / SOL The student will know, or be able to do the following. 16 - Identify the 10 major biomes. Understand how competition leads to co-evolution. The three forms of symbiosis. Look at the interactions within and among populations including carrying capacities, limiting factors, and growth curves. (Bio.8a) B. Vocabulary - behavior innate behavior habituation trial-and-error learning operant conditioning insight learning ecology population density-independent density-dependent competition resource partitioning predator - prey symbiosis mutualism parasitism succession food chain food web biome carrying capacity limiting factors growth curves ecosystem C. Laboratory Experiences 14. Succession (SLP) Anatomy – 13 days A. Concepts / SOL The student will know, or be able to do the following. - Maintenance of homeostasis (Bio.4b) - Human health issues, human anatomy, and body systems (Bio.4d) - How viruses compare with organisms (Bio.4e) - Evidence supporting the germ theory of infectious disease (Bio.4f) - Trace the path of blood, oxygen, carbon dioxide, food, and wastes through the body. - The major functions of all the body systems as well as organs that are part of the systems. - Trace the path of a reflex. - The structure of a neuron. - The types of joints and examples. - Explain how muscles work on a cellular level. - Explain how urine is produced and removed. 17 B. Vocabulary - Epidermis Corneal Layer Basal Layer Dermis Sebaceous Gland Sweat Gland Hair Follicle Subcutaneous Layer Melanocyte Mechanical/Chemical Digestion Peristalsis Esophagus Chyme Liver Gall Bladder Pancreas Bile Duodenum Jejunum Ileum Villi Cecum Ascending Colon Transverse Colon Descending Colon Sigmoid Colon Rectum / Anus Pharynx Epiglottis Larynx Trachea Bronchial Tubes / Bronchioles Alveoli Diaphragm Eurythrocytes Hemoglobin Atria Ventricles Valves Arteries Veins - Capillaries EKG Compact Bone Spongy Bone Yellow / Red Marrow Periosteum Haversian Canal Osteoblast Osteocyte Osteoporosis Axial / Appendicular Skeleton Immovable Joint Slightly Movable Joint Movable Joint Ball and Socket Pivot Plane Saddle Hinge Smooth Muscle Skeletal Muscle Cardiac Muscle Myofibril Sarcomere Z line Actin Myosin Neuron Cell Body Dendrite Axon Myelin Synapse Central Nervous System Peripheral Nervous System Motor Neurons Sensory Neurons Somatic Nervous System Autonomic Nervous System 18 - Sympathetic Nervous System Parasympathetic Nervous System Stimulus Thermoreceptor Mechanoreceptor Photoreceptor Chemoreceptor Pan Receptor - Reflex Urea / Urine Kidneys Nephrons Renal Artery Renal Vein Ureters Bladder Urethra C. Laboratory Experiences - Dissection of the fetal pig identifying muscles and internal organs specifically. Perform an EKG on a student. Allow students to observe and learn 30 individual bones. Dissect a heart, kidney, or eyeball. Body Systems (SLP) Additional Notes – - All laboratory experiences labeled with SLP can be found at the following web site from the Virginia Department of Education. Sample Lesson Plans 19