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CHAPTER EIGHT – HEREDITY Definition – Reason GENETICS 1. 2. Definition Work of Mendel His background What he studied: a. significance of his choice b. what he wanted to find out His experiments: a. Parental cross b. F1 offspring c. F2 offspring His Explanation: a. Law of Dominance how represented b. 3. Law of Segregation Genetic Terms a. Punnett Square b. Allele c. Genotype d. Phenotype e. Homozygous f. Heterozygous 4. Probability and Genetics a. Product Rule Definition Example b. Probability and Large Numbers 5. Problem Solving One trait cross Incomplete Dominance a. Definition b. Example Multiple Alleles a. b. Definition Example c. Also illustrates codominance Definition – Two Trait Crosses a. Mendel wanted to see the outcome of crosses if two traits were considered together: P.C. Pure Strain Round Yellow x Pure Strain Wrinkled Green F1 Allowed these offspring to self-pollinate F2 b. Dihybrid F2 phenotypic ratio of a dihybrid crosses: c. Law of Independent Assortment THE CHROMOSOME THEORY OF HEREDITY 1. Background: Statement A. proposed by Sutton in the early 1900’s as a hypothesis Why? B. supported by studies of Morgan worked with Drosophila 1.) Why good subject for genetic studies discovered sex chromosomes Definition Males = Females = Explains: • 50:50 chance • which parent determines the sex of the offspring • ? applies in all organisms Autosomes 1. Definition How does this relate to the Chromosome Theory of Heredity? Another Study by Morgan: 1. Worked with eye color: P. C. P.S. Red-eyes x P.S. White-eyes F1 All Red-eyes F2 3:1 (white eyes – always male) 2. Explanation: Sex-linked traits: a. Definition b. Cross to explain Morgan’s findings 3. Solving Sex-linked Problems: Examples of sex-linked traits in humans: Hemophilia, Red-Green Color-blindness Carrier Relate to Chromosome Theory of Heredity B. Study of Bridges 1. Worked with fruit fly 2. Found females with XXY and males with X Explanation: Non-Disjunction a. Definition b. Cross Relate to Chromosome Theory of Heredity Change traditional XX and XY designation: Fruit Flies – 2nd X indicates a female Humans – presence of Y indicates a male Can occur in humans: Down’s Syndrome is caused by non-disjunction of the 21st chromosome 2. OTHER GENETIC CHARACTERISTICS: a. Gene-linkage 1.) Definition Why? 2.) Example: RrYy x RrYy Ratio if genes are linked: 3.) b. c. Gene linkage and variety Example in Humans Creating variety in linked genes: Crossing over 1.) Definition 2.) Example 3.) Genetic recombination Definition 4.) Genetic Maps Definition Relationship to crossing over Multiple Genes 1.) Definition 2.) Examples 3.) Creates continuous variation Definition d. Modifier Genes 1.) Definition e. 2.) Example: eye color Gene Expression and the Environment 1.) New Definition of gene