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Transcript
Functional Medicine University’s
Functional Diagnostic Medicine
Training Program
INSIDER’S GUIDE
INTERPRETATION AND
TREATMENT:
VIRAL SCREENING
By Ron Grisanti, D.C. & Dicken Weatherby, N.D.
http://www.FunctionalMedicineUniversity.com
Limits of Liability & Disclaimer of Warranty
We have designed this book to provide information in regard to the subject matter covered. It is made available with the understanding that the
authors are not liable for the misconception or misuse of information provided. The purpose of this book is to educate. It is not meant to be a
comprehensive source for the topic covered, and is not intended as a substitute for medical diagnosis or treatment, or intended as a substitute
for medical counseling. Information contained in this book should not be construed as a claim or representation that any treatment, process or
interpretation mentioned constitutes a cure, palliative, or ameliorative. The information covered is intended to supplement the practitioner’s
knowledge of their patient. It should be considered as adjunctive support to other diagnostic medical procedures.
This material contains elements protected under International and Federal Copyright laws and treaties. Any unauthorized reprint or use of this
material is prohibited
Functional Medicine Training Program
Insider’s Guide – Interpretation of Food Allergy, Sensitivity and Intolerance
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Copyright © 2008 Sequoia Education Systems, Inc
WHAT IS A VIRUS? .................................................................................................................. 2
SOME NOMENCLATURE ............................................................................................................. 3
TREATMENT ............................................................................................................................. 4
Novel Natural Agent............................................................................................................ 4
PRACTICAL APPLICATION: CASE REVIEW .................................................................................... 5
What is a Virus?
If you can imagine something thousands times smaller than a bacteria, in fact, so small that a
traditional light microscope can not observe it. And if you can imagine that this pathogen has
been in debate whether it is alive or not yet has been known to lead to many health challenges
such as chronic fatigue syndrome, herpes, then you will know what a virus is.
Remember bacteria are stand-alone living entities able to eat, grow and reproduce. On the
other hand, viruses only become alive (so to speak) when they insert themselves into living
tissues allowing them to reproduce. It is important to understand that viruses contain only
DNA or RNA, but not both, which is why they are incapable of growth or reproduction apart
from living cells. So they must seek out a host in order to grow and multiply.
Once inside the cell, the viral enzymes literally take over the host’s functions and begin making
copies of the viral genetic instructions and new viral proteins. The new copies of the viral
genetic instructions are packaged inside the new protein coats to make new viruses.
Outside of a host cell, viruses cannot function making it dormant and unable to reproduce. For
this reason, viruses tread the fine line that separates living things from nonliving things.
However, some viruses can remain dormant inside host cells for a long time. Often they are
held in check by the immune system until the host is weakened, possibly by an infection, a
toxic exposure, a drug. Once the dormant virus is stimulated it can replicate and eventually
burst out of the host cell killing the host cell going on to infect other cells causing secondary
pathology.
Once free from the host cell, the new viruses can attack other cells. Because one virus can
reproduce thousands of new viruses, viral infections can spread quickly throughout the body.
A virus particle or virion consists of the following:
•
•
•
Nucleic acid - a macromolecule composed of chains of monomeric nucleotides that
carry genetic information or form structures within cells. The most common nucleic
acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Coat of protein - Surrounds the DNA or RNA to protect it
Lipid membrane - Surrounds the protein coat (found only in some viruses, including
influenza; these types of viruses are called enveloped viruses as opposed to naked
viruses)
Functional Medicine Training Program
Insider’s Guide – Interpretation of Food Allergy, Sensitivity and Intolerance
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Copyright © 2008 Sequoia Education Systems, Inc
Features of Viruses
•
•
•
•
•
•
Small size
cannot be viewed with a light microscope
pass through filters that retain bacteria
Characteristic shapes - spherical (complex), helical, rod or polyhedral, sometimes with tails or
envelopes.
No built-in metabolic machinery Viruses have no metabolic enzymes and cannot generate
their own energy.
No ribosomes Viruses cannot synthesize their own proteins. For this they utilize host cell
ribosomes during replication.
Only one type of nucleic acid Viruses contain either DNA or RNA (never both) as their genetic
material. The nucleic acid can be single-stranded or double stranded.
Do not grow in size Unlike cells, viruses do not grow in size and mass leading to a division
process. Rather viruses grow by separate synthesis and assembly of their components resulting
in production of a "crop" of mature viruses.
Some Nomenclature
Cytomegalovirus (CMV) – A member of the herpes family of viruses, CMV is the virus most
often transmitted to a developing child before birth. For most healthy persons who acquire
CMV after birth there are usually few symptoms, however some persons experience a
mononucleosis-like syndrome with prolonged fever and a mild hepatitis. CMV usually remains
dormant unless the person's immune system is suppressed due to drugs or disease.
Epstein-Barr virus (EBV) – A member of the herpes family of viruses, EBV infects most
people during some point of their lives. When infection occurs during adolescence or young
adulthood, it causes infectious mononucleosis 35% to 50% of the time. Symptoms of infectious
mononucleosis are fever, sore throat, swollen lymph glands and extreme fatigue. Rarely a
swollen spleen or liver involvement may develop; even more rarely heart problems and central
nervous system involvement occur. Transmission of EBV requires intimate contact with the
saliva of an infected person.
Herpes-1 Virus – A member of the herpes family of viruses, Herpes-1 is the virus that causes
cold sores. Many people infected with the Herpes-1 virus were infected as children. By the
time they're adults only 5% of those infected with Herpes-1 are bothered enough to consider it
a medical problem. Herpes-1 can be spread by a social kiss, as a relative would give to a child.
Herpes-2 Virus – A member of the herpes family of viruses, Herpes-2 is the virus that causes
genital herpes. Herpes-2 is usually spread through sexual contact with an infected person who
is shedding Herpes-2 virus at the time. Symptoms include outbreaks of painful sores on the
genitals and surrounding areas. Since the Herpes-2 virus is very similar to Herpes-1, there is
some reason to believe that prior exposure to Herpes-1 significantly reduces the acquisition of
subsequent Herpes-2 infection.
Functional Medicine Training Program
Insider’s Guide – Interpretation of Food Allergy, Sensitivity and Intolerance
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Copyright © 2008 Sequoia Education Systems, Inc
Treatment
Removing a virus is extremely difficult.
There are many prescription anti-virals on the market but none are 100% effective, and
because they usually work on the genetic material of the virus, they have also the potential of
being pro-carcinogens years later in the unsuspecting patient.
Novel Natural Agent
Monolaurin is an anti-viral agent found naturally in breast milk as well as in amniotic fluid and
also in some foods like butter and heavy cream, but especially in coconut oil. In studies
performed at the United States governments Communicable Diseases Center, CDC,
monolaurin has been able to actually dissolve the protective membrane from 14 types of
human viruses (Hierholzer). These viruses included measles, flu, herpes simplex, chickenpox,
Epstein-Barr Virus, cytomegalovirus virus (a big cause of vascular, brain and heart disease),
and SARS-type viruses.
Monolaurin actually disintegrates the lipid envelope or membrane of viruses, destroying their
main defense.
Monolaurin's activity against viruses involves its component lauric acid, binding to the lipidprotein envelope of the virus and inactivating it. By binding to the virus' coat it prevents the
virus from uncoating; now it cannot replicate and disseminate its infection throughout the body.
Also by dissolving the viral envelope, monolaurin inhibits the virus from binding to host cells
(your body) and grabbing on for dear life in preparation for releasing an onslaught of virus into
your innocent cells. Hence, two mechanisms result from the disintegration of the viral
envelope: the virus cannot attach to cells, and it cannot reproduce, since both mechanisms
depend upon an intact virus envelope.
Monolaurin 300 mg capsules (Ecological Formulas) are often taken as two capsules three
times a day at the first sign of infection and continued for a few days or weeks until the virus is
completely gone. (Hierholzer, Ismail-Cassim , Sands, Karbara, Boddie).
http://www.lauricidin.com
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Practical Application: Case Review
The following case represents a patient by the name of Laurie. She initially was seen in my
office in June of 2006 suffering with long term symptomology of herpes (Chronic Fatigue) since
1980. Her primary symptoms consisted of fatigue, difficulty concentrating, headache, muscle
aches, joint aches, feverishness, and difficulty sleeping.
Comments: The above labs reveal a confirmed viral infection. Of interest is the fact that her
LDH was outside the normal range of 200 indicating a probable viral infection. Also make note
that her SigA was significantly depressed at 6. SigA has a critical role in viral and toxin
neutralization. It was imperative to improve her primary immune function in order to achieve a
favorable outcome.
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Comments: As the above grid reveals, Laurie’s post viral labs do show improvement.
Although a small improvement she is moving in the right direction. This is more than she had
achieved over the last 10 years. As you will see on her progress questionnaires, she had
achieved both subjective and objective improvements.
Comments: This progress report clearly shows improvement and a patient who is finally
seeing a light at the end of the tunnel. Please make note that she mentions “cost” as a
frustration. I must emphasize the fact that cost on some situations “may” be an issue, however,
I can tell you first hand that the issue is NOT whether they have to think about it but rather how
they will obtain the funds to do the tests. The majority of my patients can not wait to order the
necessary labs to identify the underlying cause(s) of their health challenges. It comes down to
“you” the clinician “knowing” that the ordering of a lab or labs is going to provide a significant
piece of the puzzle to help your patient get well. That is value of mastering the science of FDM.
You will be astounded with the clinical outcomes you will achieve not to mention the referrals
you be get from satisfied patients.
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