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DEFENSE and SUPPORT: Muscular and Skeletal Systems How do these systems provide DEFENSE and SUPPORT? • Skeletal System: produces immune cells to protect against disease causing bacteria and viruses. • Muscular system: coordinates with the nervous system to help animals respond to their environment. Skeletal System Main Functions: The main organs of the skeletal system are the bones _______. Main Functions: 1. Supports & gives shape to body 2. Protects internal organs 3. Provides for movement 4. Stores minerals (calcium & magnesium) 5. Blood cells produced in bone marrow Simple Skeleton Type of support Evolutionary Trends of the Skeletal and Muscular Systems Hydrostatic Skeleton Have muscles surrounding a fluid-filled cavity . When contracted, they push against the fluid and cause the body to change shape. Exoskeleton A hard external skeleton, made of chitin and is continually shed as the organism grows - molting. Complex Endoskeleton Have a well developed Endoskeleton or internal skeleton made of calcified plates. Picture of system Examples Annelids (worms) and Arthropods (Insects) and mammals, birds, reptiles, Cnidarians (Jellyfish) Crustaceans fish, amphibians (chordates) Characteristics and Functions a. Bones are attached to other bones with special connective ligaments tissues known as _________. Arthritis – inflammation of the joint itself b. Cartilage is found at ends of bones at joints, reduces friction in movable joints (does NOT contain blood vessels) • The cartilage in the growth plates is replaced by bone, the bones become completely ossified, and the person “stops growing.” c. A place where one bone attaches to another is called a joint. 3 Types of Joints & Their Movements i. Immoveable (fixed) joint: no movement • Bones of skull; fused ii. Freely moveable: wide range of movement • Bone ends covered in cartilage iii. Slightly moveable: permit small amount of movement • Between vertebrae Types of Freely Moveable Joints 1. Ball-and-Socket Joint: Permit movement in many directions; widest range of movement of any joint (examples: shoulder and hip) 2. Hinge Joint: Permit back and forth motion (examples: elbow and knee) Types of Freely Moveable Joints • • 3. Pivot Joint: Allow one bone to rotate around another (example: neck, forearm bones) 4. Saddle (Gliding) Joint: Permit one bone to slide past another bone (example: thumb/wrist ) Bones are a living part of your body that contain nervous tissue to send and receive information, _________ nutrients as well as blood vessels to bring the __________ and ________ oxygen gas that is necessary for the bones’ health and growth. • Bone is composed of two types of tissue: – Spongy: soft, interior layer of bone tissue. • Site of red blood cell production • Less dense • Contains bone marrow – Compact: outer layer of tissue surrounding bone. • Stores minerals – Calcium. • Extremely dense and strong Photo by Steve Fruitsmaak marrow is found Bone _________ inside of bones. This tissue is responsible for creating new _______ blood cells in animals. These cells are a vital part of the ___________ circulatory system. Three Types of Bone Cells 1. 2. 3. Osteocytes – Mature bone cells that are embedded in the bone matrix. Osteoclasts – Bone cells that break down bone; Line the Haversian canals and the surfaces of compact and spongy bone. Osteoblasts – Bone cells that produce bone; Line the Haversian canals and the surfaces of compact and spongy bone. Development of Bones • *The skeleton of an embryo is composed almost entirely of cartilage. • *Cartilage is replaced by bone during the process of bone formation called ossification. • *Ossification begins to take place up to seven months before birth. • *Osteoblasts secrete mineral deposits that replace cartilage osteoblasts become surrounded by bone tissue mature to osteocytes Organization of Life: Skeletal System OSTEOCYTES Compact or Spongy Femur, Tibia, Vertebrae, Skull SKELETAL Skeletal Body System Interactions: • Circulatory System: bones help produce new blood cells in addition to storing minerals transported by the circulatory system. • Muscular System: bones and muscles work in opposing pairs to perform body movement. Muscles and bones support, protect, and maintain posture for the human body. • Nervous System: bones protect many vital organs of the nervous system – Skull (brain), Vertebrae (spinal cord). Skeletal System Disorders • Arthritis – inflammation of the joint itself • Kyphosis (hunchback) – curvature of upper spine PROBLEM: Osteoporosis is a weakening of bones due to loss of calcium that is more common in older women =Increased risk for fracture Dowager’s hump Change in Bone Density over Time What can be done now about bone loss? •Eat foods containing calcium, magnesium and phosphorous now (as teens) why you still are building bone mass. • Continue weight-bearing exercises throughout your life to keep the bone mass you built earlier on. Bones in the Human Skeleton Here are the main bones everyone should know. Where is your FUNNY BONE?!?!?? Muscular System: The main organs of the muscular system are the muscles. There are 3 types of muscles tissue made up of individual muscle cells, called fibers. Types of Muscles: Skeletal Muscle These muscles are usually 1. _________________: bones and allow for the movement of attached to _______ limbs Since these muscles can be controlled by a ______. the organism, they are known as __________ voluntary muscles. These muscles also help maintain our posture and protect internal organs. This type of muscle is striated. Types of Muscles: Smooth Muscle This type of muscle is found 2. ________________: intestines within the walls of organs like the ___________, diaphragm allowing these _________, bladder and the __________ Why it is expand and ________. contract Smooth organs to ________ called smooth! muscle is not under conscious control, so it is involuntary muscle. Is NOT striated. known as ____________ Image by Theresa Knott -Smooth muscle also helps move food through your digestive tract via the process Peristalsis. Types of Muscles: Cardiac Muscle This type of muscle is 3. _______________: not under your control, so it is also involuntary It is only found in considered ____________. heart which is why it is called the _______ cardiac muscle. Is striated. ________ How Muscles and Bones Interact a. Skeletal muscles are joined to bones by tough connective tissues called tendons. – Tendons pull on the bones and make them work like levers. – The muscles provide the force to move the lever. – Usually, there are several muscles surrounding each joint that pull in different directions. How Muscles and Bones Interact a. Most skeletal muscles work in opposing pairs. When one muscle contracts, the other relaxes. – The muscle that contracts is the flexor while the muscle that lengthens and relaxes is the extensor • In order for the biceps muscle to contract (flex) the triceps muscle has to relax. Therefore the biceps is your flexor muscle while your triceps is your extensor muscle. energy c. Muscles use a large amount of ________. This requires them to produce large amounts of the ATP These molecules energy molecule called _____. are produced in the _____________ mitochondria through the process of cellular respiration. This is why there are a greater than average number of mitochondria in ________ muscle cells. d. Cellular respiration requires the body to O2 cannot be oxygen gas. When ____ absorb ________ absorbed fast enough, the body produces a lactic acid compound known as __________. Disorders to worry about • Black widow bite – releases more ACH = muscle spasms • Botox – blocks release of ACH from neurons paralyzing the muscles in your face = no wrinkles • Tetanus- infection causing muscle spasms to develop by blocking motor neurons – Lockjaw, neonatal tetanus Organization of Life: Muscular System Tissue Cell Skeletal Muscle Fiber Smooth Cardiac Organ Bicep Stomach Heart Organ System Muscular System Muscular Body System Interactions: • Digestive System: smooth muscle found in the stomach and intestinal tract helps move digested food through the body. • Circulatory /Respiratory System: products of cellular respiration (CO2, lactic acid) from the muscular system are removed via the blood stream. • Nervous System: signals muscles to contract for movement and response to environmental stimuli. LABEL THE FOLLOWING MUSCLES ON YOUR PICTURE. Quadriceps Hamstrings Quadriceps DEFENSE Integumentary, Immune and Lymphatic Systems DEFENSE How do the integumentary, immune and lymphatic systems work together to defend the body? These systems work together to keep pathogens _______________ out of the body and to attack ____________ any that make it in. Functions of the Integumentary System protective barrier for 1. Acts as a __________ internal organs and tissues. pathogens like bacteria and 2. Prevents __________ viruses from entering the body. 3. Helps to regulate the body’s temperature by sweating or forming ____________ “goose bumps”. Regulating Temperature Homeostasis When you sweat, your body saltwater onto the places __________ surface of your skin. Water can heat absorb large amounts of ______ before it evaporates. Because the water absorbs the heat then Skin and hair also help the body _______ heat when it is cold. carries it away, your body can keep itself from ____________. overheating Skin and hair also help retain heat the body _______ when it is cold. Homeostasis The dermis is abundantly supplied with blood vessels that play a role in maintaining body temperature homeostasis. If Cold: Blood vessels in the dermis narrow, helping to limit heat loss. Blood bypasses the dermis capillaries temporarily, which allows internal body temperature to stay high. If Hot: Blood vessels widen, bringing heat from the body's core to the skin and increasing heat loss. Skin becomes reddened and warm and allows body heat to radiate from the skin surface. Functions of the Integumentary System D when exposed to 4. Makes vitamin __________ UV light. (Fat-soluble vitamin that promotes absorption of calcium and phosphorus.) 5. Prevents the body from becoming dehydrated due to excess water loss. ___________ excretion of waste like urea 6. Aids in _________________, and salts. sensory organ 7. Acts as a ______________by detecting heat, cold, pressure, and pain Evolutionary Trends The different phyla of animals have unique very ___________ structures that are a part of their integumentary systems which allow them to ____________ to adapt their environments. Evolutionary Trends of Integumentary System Complex Simple Animal Taxon Invertebrates Adaptations epithelial cells secrete mucous; shells and exoskeletons made of chitin; stinging or sharp outer cells Fish Mucous secreted over scales decreases friction in the water Amphibians Have mucous glands to keep skin moist to help with respiration and body temperature Reptiles Birds Feathers to fly; Dry, scaly skin glands secrete made of keratin to oily substances prevent water loss to keep feathers and regulate body waterproof; temperature colorful for communication Picture of Adaptation Jellyfish, worms, Examples insects, crustaceans Fish Frogs, Toads, Alligator, Lizards, Salamanders Snakes Birds Integumentary System in Mammals The main organ of the integumentary system is the _____. skin It contains three layers epidermis known as the________, dermis and the ______, Hypodermis (subcutaneous) ___________________ __, which is the underlying layer of fat for insulation. ______ MAMMALS 1. Epidermis • outer layer approximately 10-30 cells thick pores • covered in __________ • Hair and nails protude from this layer • contains melanin pigment that gives skin its color 2. Dermis • thickest layer • contains blood vessels, muscles, nerves, hair sweat glands follicles, _______ and subaceous (_____) oil glands Epidermis • Outer layer of skin • Does not contain blood vessels • Contains two layers 1. Outside of the epidermis is made up of dead cells and comes into contact with the environment. 2. Inner layer is made up of living cells and undergo rapid cell division, producing new cells that push older cells to the surface of the skin (shed once every 4-5 weeks) o o Keratin – tough protein made here that eventually forms the waterproof covering for your skin. Contain melanocytes, which produce melanin. o Melanin is a dark brown pigment that helps protect the skin from damage by absorbing UV rays from the sun. o Differences in skin color are caused by the different amounts of melanin the melanocytes produce. o NO BLOOD VESSELS here, therefore when you slightly scratch your arm it doesn’t bleed! Dermis • Inner layer of the skin – Located between the epidermis and the hypodermis. • Contains: 1. 2. 3. 4. Collagen fibers Blood vessels Nerve endings Glands 1. 2. 5. 6. 7. Sweat glands – body perspires when too hot Oil glands (sebaceous) – produces oily secretion (sebum) to keep skin flexible and waterproof Sensory receptors Smooth muscles Hair follicles Integumentary System Levels of Organization Epithelial Epidermis, Dermis Skin Integumentary Fun Fact: Believe it or not, the largest integumentary system is the ________ organ system and your _____ skin is the largest organ in your body. Interaction with Other Body Systems Skin is the first line of defense in the immune system response. The circulatory system and skin regulate body temperature. Skin and the excretory system excrete water, urea, salts, and other wastes through sweat. Receptors of the nervous system are located in skin. Immune System: The main function of the immune system is to fight infections white off ___________. This is the job of the ________ antibodies they create. blood cells and the ___________ Immune System: White blood cell travels throughout the body through circulatory system. This allows them to be the ___________ distributed to every part of the body. ___________ A substance that triggers this immune response is known as an antigen. Examples of Antigens: Bacteria, Viruses, and Other Pathogens. Cells that recognize specific antigens (lymphocytes): 1. 2. 3. B Lymphocytes (B Cells): Provide immunity against pathogens and antigens in body fluids. T Lymphocytes (T Cells): Provide a defense against abnormal cells and pathogens inside living cells. Phagocytes: Large cells that eat pathogens and damaged cells. Types of White Blood Cells: Macrophages - These cells ______________ engulfing kill bacteria by __________ them (process known as _____________). This means phagocytosis that they pull the pathogen inside of themselves where the pathogen is trapped and digested by proteins __________ enzymes These called __________. cells are made in bone marrow. ________ B cells - These cells antibodies to make ___________ fight inside body fluids. Memory B cells are also responsible for “remembering” a specific bacteria or virus. This causes your immune body to be __________ to them in the future. Immune:antibody/antigen response https://www.youtube.com/watch?v=lrYlZJiuf18 https://www.youtube.com/watch?v=MI-BLaj5nFk https://www.youtube.com/watch?v=zQGOcOUBi6s Antibodies are an important part of the immune system. Once they antigen attach to an _________(substance that triggers immune response), they can prevent further infection and spleen to signal the ______ liver and _______ destroy the toxic invaders. Immune Response • When a pathogen invades the body, its antigens are recognized by a small fraction of the body’s B cells…these cells then release antibodies. – Antibodies - Proteins that recognize and bind to antigens. • Carried in the bloodstream • As the antibodies overcome the infection, the plasma cells die out and stop producing antibodies. Types of White Blood Cells: T Cells - These white blood cells actually _________ attack inside the body’s cells which contain viruses They also target and bacteria or _________. ________ tumor cells which are the root of all destroy ________ cancers. When a virus or cancer begins to invade your body, antibodies alone cannot destroy them. T cells divide and become specific to kill the infected cells: Killer T cells – track down and destroy the tissue containing the antigen Helper T cells – produce memory T cells (able to activate killer T and B cells) Suppressor T cells – release substances that shut down the Killer T cells after the antigens are under control. A breast cancer cell above and a prostate cancer cell below being attacked by Killer T Cells Penicillin and other ___________ antibiotics can also be used to help the immune system, but it is important that you bacteria understand that antibiotics only kill _________! They will NOT help if you are sick with a virus _____ because viruses are not cells! H.I.V. Human Immunodeficiency Virus A.I.D.S. H.I.V. is the virus that causes __________, or acquired immune deficiency syndrome. It attacks a Helper T cell. special T cell known as a __________ The lymphatic system removes fluid from around cells and filters out pathogens. When this fluid passes through the lymph nodes white blood cells _____________, attack and kill any pathogens. When bacteria and other pathogens travel through the lymph nodes, they are attacked by white blood cells. This causes swell • the lymph nodes to ______. Lymphatic system also collects fluid lost by the blood and returns it to the circulatory system Organs in the Lymphatic System • Lymph nodes (densely packed area of tissue that filters lymph and traps microorganisms) • Lymph vessels (run along side veins collecting and carrying lymph back to the circulatory system) • Lymph (fluid found in lymph vessels) • Spleen (Removes damaged red blood cells from blood) • Tonsils (Pair of enlarged lymph nodes in throat) • Thymus gland (Location where some white blood cells mature) Evolutionary Trends of Lymph & Immune Systems Complex Simple Animal Taxon Adaptations Examples Invertebrates Cells recognize peptidoglycan, a substance found in the cell walls of bacteria, and destroy the bacteria bees, flies Fish Thymus makes T lymphocytes and B cells Fish Mammals Body produces antibodies specific to certain pathogens Human Lymph & Immune System Levels of Organization White Blood Cells, B-cells, Tcells, macrophages Lymph nodes, bone marrow Spleen, Liver Lymph and Immune Interactions with other Body Systems Skin of the integumentary system is the first line of defense of the immune system. The circulatory system transports immune cells around the body. It also helps control body fluids with the lymphatic system. The excretory system excretes excess fluids and pathogens. Bones of the skeletal system produce lymphocytes and macrophages.