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Transcript
The Master Gland/Pituitary
…
http://video.google.com/videoplay?docid=5967601337386159265&q=endocrine+system&total
=93&start=0&num=10&so=0&type=search&plindex
=1
Endocrine glands and hormones
Hormones are carried through
† The
endocrine
system is
composed of a
series of ductless
glands
the blood
…
It communicates
through the use of
hormones Negative
feedback system**
…
http://video.google.com/videoplay?docid=61721
05265971673087&q=Pituitary+gland&total=68
&start=0&num=10&so=0&type=search&plindex=
1
Pituitary Gland**
Growth Hormone (GH)
Too much GH
…
…
…
…
enlarged hands & feet**
**Acromegaly: (↑
GH) irreversible
**enlarged hands &
feet, ↑ Hair growth**
painful joints muscle
weakness,
**Risk of falls
Pituitary Gland
Growth Hormone (GH)
Too much Growth Hormone
…
…
…
Acromegaly:
(↑ GH) irreversible
enlarged cranium and
jaw, bulging forehead,
thick lips, big tongue
enlarged cranium and jaw,
Pituitary Gland
Growth Hormone (GH)
Too much Growth Hormone
…
…
Gigantism (↑ GH)
↑ long bone length ↑
height, weakness
Pituitary Gland
Growth Hormone (GH)
7feet 7.5 inches/size 26 shoe
7 feet 8 inches
Pituitary gland tumor
Pituitary Gland
Growth Hormone (GH)
TOO little growth Hormone
†
†
†
†
†
Abnormally short height
Normal body proportion
Appear younger than age
Dental problems due to
underdeveloped jaws
Delayed sexual
development
dwarfism
Pituitary Gland
Growth Hormone (GH)
TOO little growth Hormone
dwarfism
Abnormally short
height
† Normal body
proportion
† May produce normal
children
†
Pituitary Gland / Oxytocin
…
Oxytocin: Releases milk and stimulates contractions
in labor
Pituitary Hormone ADH**
…
…
…
…
Antidiuretic Hormone: ADH**
a diuretic helps to release water/urine from the
kidneys
An anti diuretic slows down that release of
water/urine
ADH Causes kidneys to conserve
water/urine
Pituitary Gland
Antidiuretic Hormone (ADH)
Too much ADH = SIADH
…
Syndrome Of
Inappropriate Secretion Of
Antidiuretic Hormone:
SIADH too much ADH
…
…
…
…
kidneys reabsorbs water
yet urine output ↓
fluid overload causing
hyponatremia (sodium
levels ↓, )**
…
…
water intoxication,
without edema
weakness, cramps
↓ appetite, nausea,
headache, diarrhea,
weight gain, seizures
Pituitary Gland
Antidiuretic Hormone (ADH)**
↓ ADH = Diabetes Insipidus**
…
Symptoms can look like psychosis
Causes urine to be
diluted
…
Urine won’t concentrate
…
May cause dehydration
…
↑ sodium levels
Diabetes Insipidus
Like a sieve
Urine won’t concentrate
†
Polyuria **
†
polydipsia**
„
„
†
Excessive urination
Excessive thirst
Dry skin; poor skin
turgor** (normal
elasticity in skin)
Thyroid gland abnormalities
Thyroid gland Hormones
Thyroid Stimulating Hormones
(TSH)**
…
…
TSH**
Action of hormones
…
†
Thiroxine** (T4)
…
†
Triiodothyronine
…
Calcitonin causes ↓ in
calcium in blood
Metabolism
Nervous system
activity
Growth and
Development
Hyperthyroidism k TSH
GRAVES DISEASE**
…
…
…
…
…
↑ Thyroid Stimulating
Hormones
↑ metabolic processes
edema in neck
bulging eyeballs,
dysphasia
Exophthalmia
Thyroid Stimulating Hormones
Hyperthyroidism
…
…
…
…
…
Graves Disease **
↑ appetite,
↑ activity level,
nervous, jittery,
↑ pulse and temp,
insomnia
Treatment for Hyperthyroidism
…
…
Soft food due to dysphagia
Tyroidectomy is dangerous
† Thyroid storm (after surgery)
can lead to death** (rare)
† It can cause death due to
Congestive Heart Failure**
Radioactive iodine common
treatment
Hypothyroidism
…
Role Play Time
Thyroid Stimulating Hormones
Hypothyroidism = ↓TSH
…
…
…
…
…
…
Hypothyroidism
↓ metabolism
↓ body temp
↓ memory/slow thinking
↓ B/P
↓respirations
↓ libido
Hypothyroidism = ↓TSH
Most Common disorder in US
Treat with Levothryroxine**
…
…
…
…
…
…
…
intolerance to cold
Weight gain
Depression
Impaired memory
Lethargic
Anorexia
Constipation
Thyroid Stimulating Hormones
Goiter:
…
…
…
…
↓ iodine causes Goiter
due to poor diet
↓TSH which causes
↑ in thyroid gland size
Goiter:
Parathyroid glands ( 4 glands)
Hyperparathyroidism
…
…
Hypoparathyroidism
Hypercalcemia: excess of
calcium in the blood
…
…
causing
†
†
†
†
†
†
tetany (spasms)
stridor, harsh vibrating sound heard during
Calcium leaves bones and goes
into blood.
Causes bone pain, muscle
weakness, fractures
…
kidney stones
respiration
…
heart impairment
cyanosis
numbness in skin,
anxiety
depression, ↑ phosphorus
…
…
Chvostek’s and Trousseau’s signs
showing not enough calcium in
blood**
Parkinson-like syndrome
AArenal Gland
Adrenal Glands hormones
1.Sex hormones
… Androgens (male)
…
Estrogens (female)
2.Mineralocorticiod
Regulate sodium and
potassium
3.Glucocorticoid **
…
…
Helps body respond to stress
Maintains glucose regulation
4. Epinephrine(adrenaline)
5. Norepinephrine
Adrenal hyperfunction
(Cushing’s syndrome)**
Overstimulation of
pituitary gland
† Excessive corticosteroids
and glucocorticoids
† Liver releases Glucose
† Diet low in Sodium*
†
Cushing’s Disease
…
http://video.google.com/videoplay?docid=89913
6968133664999&q=CUSHINGS+DISEASE&total=
29&start=0&num=10&so=0&type=search&plinde
x=4
Cushing's Disease**
adrenal
Buffalo Hump
†
†
†
Susceptible to infections
Depression
Loss of libido
Moonface *
Buffalo hump*
† Weight gain*†
†
Addison's Disease
Adrenal hypo functon
„
„
„
„
„
„
Extreme weakness
Darkly pigmented skin and
mucous membranes
Loss of appetite/ Weight loss
Hypoglycemia: abnormal
decrease of sugar in the blood
Hyponatremia
Hyperkalemia abnormally high
concentration of potassium in
the blood
Adrenal
President Kennedy had Addison’s