Download CENTRO ESCOLAR UNIVERSITY Biological Sciences Department

CENTRO ESCOLAR UNIVERSITY
Biological Sciences Department
Manila*Malolos*Makati
SYLLABUS
PRBS 131
Course Number
I.
BIOSCI131
Course Title
CELL BIOLOGY
Descriptive Title
3 units
Credit Unit(s)
3 hours lec
Hour(s)/Week
COURSE DESCRIPTION
This course deals with the study of cells in higher organisms, specifically a discussion of the following: molecules that make up cells and their
interactions; structures of the cells and their functions; cell growth and oncogenic transformation transport and cell signaling and communications;
cytoskeleton and the extracellular matrix; chromatin structure and RNA synthesis; genetic mechanisms of heritability of characteristics; and cell movements.
II.
COURSE OBJECTIVES
A.
General Objectives:
Determine structures and functions that make the cell as a vital unit of the organism.
B.
Specific Objectives:
1.
Seeks to explain the physiologic changes in living things as affected by their physico-chemical and metabolic processes of cellular parts;
2.
Find out how the organelles perform their roles in the maintenance and sustenance of life;
3.
Relate how this unit of structure of living things is affected by real life conditions.
Page 1 of 6
Licensure Exam for Teachers (LET) Table of Specification (TOS) Competencies
1. Describe the development of Cell Theory
2. Differentiate prokaryotic from eukaryotic cell
3. Compare the structure and function of a plant and an animal cell
4. Explain the process of transporting materials into and out of cell
5. Describe the basic processes of mitosis and the result of its malfunction
6. Describe the basic processes in meiosis
SPECIFIC OBJECTIVES
Prepare a model of prokaryotic and
eukaryotic cells using modeling clay as
medium.
CONTENT OUTLINE
TIME
ALLOTMENT
EVALUATIVE
MEASURES
4.5 hours
Quizzes & exams
Pre-test and Posttest
Take- home
assignments
Unit I - INTRODUCTION TO CELLS
1. Unity and diversity of the cells
2. Cells under the microscope
Describe the different model organisms and 3. Prokaryotic cells
4. Eukaryotic cells
identify their applications in cell biology
5. Model organisms
studies.
Discuss the various molecules and
macromolecules and their functions in the
biological system.
TEACHING STRATEGIES
Lecture-Demonstration and
Discussion
Preparing models of various
cell types
Post- test and Pre-test
Unit II- CHEMICAL COMPONENTS
OF THE CELLS
1. Molecules in cells
2. Macromolecules in cells
Lecture-Demonstration and
Discussion
Post- test and Pre-test
4.5 hours
Quizzes & exams
Pre-test and Posttest
Take- home
assignments
Page 2 of 6
SPECIFIC OBJECTIVES
CONTENT OUTLINE
TEACHING STRATEGIES
TIME
ALLOTMENT
EVALUATIVE
MEASURES
PRELIM EXAMINATION
Unit III- BIOCHEMICAL
ENERGETICS
Explain the various pathways of
metabolism in prokaryotic and eukaryotic
cells.
1. The use of energy by the cells
2. Enzymes as biological catalysts
3. Metabolism
Lecture-Demonstration and
Discussion
4.5 hours
Video Presentation
Quizzes & exams
Pre-test and Posttest
Take- home
assignments
Concept Mapping
Unit IV- STRUCTURE OF THE
BIOLOGICAL MEMBRANE
Understand the role of the biological
membrane in various physiological
activities of the cell.
Prepare a concept map to explain the
mechanisms by which nerve impulses are
generated.
1. The chemical composition of membranes
2. Principles of membrane transport
3. Transporters and their functions
4. Movement of substances across the
membrane
5. Ion channels and membrane potentials
6. Membrane potentials and nerve impulses
Post- test and Pre-test
Group discussion
6 hours
Unit V- ENERGY GENERATION &
MITOCHONDRIA
Compute for the total energy generated in
aerobic respiration in prokaryotes and
eukaryotes.
1. Mitochondrial structure and function
2. Oxidative metabolism in the
mitochondrion
3. The role of mitochondria in ATP
synthesis
4. Proton- motive force and the machinery
of ATP formation
6 hours
Page 3of 6
SPECIFIC OBJECTIVES
CONTENT OUTLINE
Unit VI- PHOTOSYNTHESIS & THE
CHLOROPLAST
TEACHING STRATEGIES
TIME
ALLOTMENT
Group discussion
Lecture-Demonstration and
Discussion
4.5 hours
Prepare a schematic diagram to illustrate
the different stages and enzymes involved
in photosynthesis.
1. Overview of the photosynthetic
mechanism
2. Photosynthetic units and reaction centers
3. Photophosphorylation
4. Carbon dioxide fixation and the synthesis
of carbohydrates
EVALUATIVE
MEASURES
Quizzes & exams
Video Presentation
Pre-test and Post-
Concept Mapping
test
Take- home
Post- test and Pre-test
assignments
MIDTERM EXAMINATION
Unit VII- CELL COMMUNICATION
Discuss the different types of receptors
involved in cell signaling.
1. General principles of cell signaling
2. G- protein coupled receptors
3. Enzyme- coupled receptors
Unit VIII- CYTOSKELETON & CELL
Construct a table that shows the differences MOTILITY
among the different types of filaments that
make up the cytoskeleton.
1. Microtubules
2. Intermediate filaments
Prepare a flowchart to discuss the process
3. Microfilaments
of muscle contraction.
4. Muscle contractility
4.5 hours
Group discussion
Quizzes & exams
Pre-test and Post4.5 hours
test
Take- home
assignments
Unit IX- THE CELL DIVISION CYCLE
Create a visual representation of the cell
division cycle in eukaryotic cells.
1. Overview of the cell cycle
2. Cell cycle control system
6 hours
Page 4of 6
SPECIFIC OBJECTIVES
CONTENT OUTLINE
TEACHING STRATEGIES
3. S Phase
4. M Phase
5. Cytokinesis
6. Control of cell number and cell size
Lecture-Demonstration and
Discussion
Unit X- DNA REPLICATION &
REPAIR
Concept Mapping
1. DNA Replication
2. DNA Repair
3 hours
Group discussion
Quizzes & exams
Unit XII.- STEM CELLS AND CANCER
Report journal articles that features genes
involved in cancer.
Discuss how stem cells can be used in the
treatment of cancer.
1. Tissue maintenance and renewal
2. Basic properties of cancer cells
3. The causes of cancer
4. The genetics of cancer
Pre-test and Post4.5 hours
Demonstrate how MHC plays an important
role in activation of T lymphocytes.
Prepare a model that shows the different
types of antibodies.
1. An overview of the immune response
2. The complementary system
3. Major Histocompatibility Complex
4. Activation and mechanism of action of T
lymphocytes
5. Signal transduction pathway in
lymphocyte activation
6. The clonal selection theory
7. Structure of Antibodies
test
Take- home
assignments
Unit XIII- THE IMMUNE RESPONSE
Construct a concept map which illustrates
the activation of the pathways of
complementary system.
EVALUATIVE
MEASURES
Video Presentation
Post- test and Pre-test
Prepare a model to illustrate the process of
DNA replication and repair.
TIME
ALLOTMENT
Special reports
6 hours
FINAL EXAMINATION
Page 5 of 6
III.
READING MATERIALS
Books:
Alberts, Bruce. et al, 3rd Edition. Essential Cell Biology. New York: Garland Science, 2010
Tompkins, Susan, 2010. Cell Biology. Oakville, On: Apple Academic Press, 2010.
Karp, Gerald C. Molecular Biology Concepts and Experiment 6th Edition. Wiley & Sons, Inc. c 2010
Prasad, S. N. Cell Biology. New Delhi: Campus Books International, 2008
Journals
Advances in Molecular Biology
Biochemistry & Cell Biology
BMC Cell Biology
Cells
DNA & Cell Biology
International Journal of Cell Biology
Journal of Cell & Molecular Biology
Nature Cell Biology
Nature Reviews Molecular Cell Biology
Prepared by:
Approved by:
Dr. Maricar W. Ching
Faculty (Cell Biology)
Dr. Zenaida D.R. Los Baños
Head, Biological Sciences Department
Date Approved: ________________________
Page 6 of 6