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RNA editing After Transcription, the mRNA strand goes through some changes before Translation. Much like the first draft of a paper you write, many mRNA molecules require some editing before Translation at the ribosome. The genes in eukaryotic DNA contain sequences of nucleotides that do not code for amino acids. These sequences are called INTRONS. The sequences in a gene that DO code for amino acids are called EXONS. During Transcription, both introns and exons are transcribed. However, the introns are cut out of the mRNA strand while it is still in the nucleus. The remaining exons are spliced together to form the final mRNA strand. Other modifications to the mRNA strand An "mg-cap" is added to the beginning of the mRNA strand. This cap helps the mRNA strand position itself in the ribosome so that the start codon (AUG) is the first codon translated in the protein. A "poly-Adenine tail" is added to the end of the mRNA strand. This poly-A tail slows down the digestion of the mRNA strand into RNA nucleotides. This insures the mRNA strands are not digested prior to Translation into a protein. mg-cap This final mRNA is ready to be translated into a protein sequence.........or is it????