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Chapter 38 Digestive & Excretory Systems What’s this pic saying? Digestion Where does all the energy come from for all everything in your body like nerve impulses (signals) & muscle contractions? Digestion • *Breakdown of food into small molecules • Two main reasons for this – *Energy; turn glucose ATP* – *Nutrition - need building materials for new cells, new tissues, and tissue repair* • DNA from your food is broken down into nucleotides – reassembled into your DNA’s code during DNA replication • Protein-rich meats are broken down into amino acids – reassembled during translation to make more proteins • Lipids for cell membranes (phospholipid bilayer) Nutrition - Building Blocks from Food Nutrients ***Water ***Carbohydrates ***Lipids (fats) ***Proteins Function in Body Makes up the bulk of blood, lymph, and cytoplasm Essential for most cellular processes Helps regulate body temperature, blood pressure Main energy source for the body. Used to create cell membranes, myelin sheaths, & hormones. Provides support, protection, insulation for body organs. Long-term energy storage. Growth & repair of structures like skin & muscle. Regulate movement of molecules into cells (protein pumps & protein channels). Vitamins Organic molecules that help regulate chemical reactions – called coenzymes (allow the enzyme to actually bind to its substrate) Minerals Inorganic nutrients used to make bone, teeth, hemoglobin, and help neurons function: Ca, Fe, Mg, Na, K The Gastrointestinal Tract • Alimentary canal - *a single tube that runs from mouth to anus* • Organs/parts: – mouth, pharynx, esophagus, stomach, small intestine, large intestine • Glands: – Salivary glands, pancreas, and liver – add their secretions to the digestive system The Digestive System Pharynx Mouth Salivary glands Esophagus Liver Gallbladder (behind liver) Stomach Pancreas (behind stomach) Large intestine Small intestine Rectum Basic Steps of Digestion 1. *Break down food from macromolecules to smaller molecules (polymer monomer) • • Mechanical – physically make smaller pieces Chemical – breaking bonds to make smaller molecules 2. *Absorb small molecules into the blood. 3. *Distribution to the rest of the body cells (“internal transport system”) Mouth • Mechanical – teeth cut & grind food • *Chemical – salivary glands secrete salivary amylase – *Breaks down polysaccharides into monosaccharides • *Rear part of throat* – Accommodates both food & air from mouth and nasal passages • Tongue pushes food toward it – Bolus – chewed clump of food and enzymes • Epiglottis – Small flap of cartilage – closes so food doesn’t enter respiratory tract Pharynx Esophagus • *Muscular tube that connects pharynx with stomach* • Peristalsis is the muscular contractions that push food to stomach *Stomach– HCl (hydrochloric acid) helps breaks food into smaller pieces protein digestion • Also makes the stomach acidic to • Mechanical activate other enzymes – Mucus – secreted to help protect lining of stomach from the acid – Mixture is now churned into chyme • Chemical – *Pepsin begins the breakdown of proteins into amino acids* • Activated by the HCl • 8 essential amino acids are found in meats, fish, eggs, milk – vegans must be sure to eat various plant groups to get these • valve at bottom of stomach opens to release chyme into small intestine Small Intestine • 3 parts (it can be 7 meters long!) – Duodenum Jejunum Ileum • Both mechanical & ***chemical digestion* • *Enzymes added by the pancreas & liver* • Where *absorption of nutrients, vitamins, & minerals happens* The Liver and the Pancreas Liver Bile duct Gallbladder Pancreas Duodenum Pancreatic duct To rest of small intestine *Liver & Pancreas Release into the Small Intestine to digest* • From the liver… – Bile = Mechanical Digestion – Emulsifies fats - acts like a detergent to break large fats into smaller ones that the lipase can chemically break down – Bile is stored in gallbladder until needed • From the pancreas … – Releases sodium bicarbonate (NaHCO3) to neutralize acidic stomach secretions – Chemical Digestion • Amylase – resumes carbohydrate digestion • Trypsin – continues protein digestion • Lipase – completes fat digestion – Also regulates blood sugar levels *Small Intestine=most absorption of nutrients* • Most absorption of nutrients to blood occurs in the jejunum & ileum • Inner surface is a series of folds called villi and microvilli that increase surface area used for absorption – have lots of capillaries running over them to do this (like the alveoli in the lungs) *Large Intestine (colon)=remove water* • Chyme is now almost devoid of nutrients – Only water, cellulose, & undigestible material left • *Large Intestine takes out extra water • E. coli colonies live here off the undigestible materials – produces vitamin K • *Undigestible materials are compacted, collected in rectum, & expelled through anus The Digestive Enzymes Site Enzyme Role in Digestion Mouth Salivary amylase Breaks down starches into disaccharides Stomach Pepsin Breaks down proteins into large peptides Small intestine (from pancreas) Amylase Continues the breakdown of starch Trypsin Continues the breakdown of protein Lipase Breaks down fat Maltase, sucrase, lactase Breaks down remaining disaccharides into monosaccharides Peptidase Breaks down dipeptides into amino acids. Small intestine Glucagon=hey your glucose is gone Insulin- sends sugar into cells for cell resp. Excretion How do we get rid of the other wastes we create in every chemical reaction? A filter you may be familiar with • Have you ever seen a waterpurification system attached to a faucet? • This system removes impurities from water such as arsenic or other chemicals that can be harmful to people. Water passes through the filters in the system; the impurities are trapped on the surface of the filters. Eventually, the water that comes out of this purifier is free of the impurities. Your Body’s Filter • 1. Your body has its own system for filtering blood. Why might the blood in your body need to be filtered? • 2. What organ(s) do you think filters your blood? • 3. How do you think the filtered materials leave your body? What kind of waste do we make? • Excess water, salts, carbon dioxide, and urea – Urea is made from nitrogen of proteins that we’ve broken down for energy • Excretion means getting rid of waste •Filter •Detoxify stores glycogen- make bile •Releases enzymes and hormone insulin •Protein digestion The Excretory System • Skin – excretes excess H20 and salts (some urea) • Lungs – excrete CO2 • Liver – turns excess amino acids into urea • *Kidneys – *Filters blood of toxins – *Removes excess water – *Regulates pH of blood Kidneys - main excretory organs • 2 bean-shaped organs – size of a closed fist • Renal artery – enters each kidney with unfiltered blood (full of toxins) • Renal vein - leaves each kidney with filtered blood (rid of toxins) • A ureter leaves each kidney carrying waste filled fluid (urine) to urinary bladder for storage • The urethra is a duct that releases urine from the bladder to the external environment How the Kidney Filters • *Made up of nephrons*** – *Each is a separate little filtering system (1 million) 1. *Blood enters kidney through the renal artery 2. *Blood flows into the nephron in small arteries and is filtered – Water, salts, urea, glucose & amino acids are filtered out (the filtrate) in the Bowman’s capsule – Salts, amino acids, fats, sugars are removed from filtrate by active transport and put back into the blood (reabsorption) 3. * (Filtered fluid now called urine) & flows through a duct called the Loop of Henle – Urine gets concentrated when water moves back into blood via osmosis 4. *Urine empties into the ureter that leads to the bladder for storage 5. *Purified blood leaves through renal vein to return the body Structure of the Kidneys Kidney Nephron Bowman’s capsule Cortex Capillaries Glomerulus Medulla Renal artery Renal vein Ureter Collecting duct Vein To the bladderArtery To the ureter Loop of Henle Renal artery glomerulus Bowman’s capsule Loop of Henle Ureter bladder FYI Kidney Dialysis Blood in tubing flows through dialysis fluid Blood pump Vein Artery Used dialysis fluid Shunt Air detector Dialysis machine Fresh dialysis fluid Compressed air The digestive enzymes in the table function in some organs to perform the chemical digestion of food. The major organs of the digestive system are the esophagus, large intestine, mouth, pharynx, small intestine, and stomach. A. List these six organs in the order in which food passes through them. B. Identify which of these organs is primarily responsible for absorbing nutrients from digested food. C. Describe the functions of two of the organs listed other than the one you identified in part (b). • Milk is an important part of many people’s diets. When the word milk is mentioned, most people think of dairy milk derived from cows. Many people, however, cannot drink dairy milk because of lactose intolerance. Individuals with this condition are unable to digest a component in the milk called lactose. Lactose is the sugar in dairy milk. It is a disaccharide made from the sugars glucose and galactose. Lactose-intolerant individuals lack the enzyme lactase, which is needed for the digestion of lactose sugar. • Many lactose-intolerant individuals drink soymilk instead of dairy milk. Soymilk is produced from soybeans (the seeds of the soybean plant) and is a nutritious substitute for dairy milk. Soymilk contains protein, calcium, and other essential nutrients just as dairy milk does. • The table below compares some of the nutrition information for a serving of dairy milk and a serving of soymilk. • Dairy Milk and Soymilk Nutrition Information Chart The digestion of dairy milk or soymilk provides the body with important nutrients 1. Describe how the digestive system converts the carbohydrates, proteins, and fats in dairy milk or soymilk into nutrients that can be used by cells. Include the body parts and organs involved. 2. Describe how the nutrients in the digestive system are made available to cells throughout the body after digestion has occurred. Include the body parts and organs involved.