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The Skeletal System You will have a working knowledge of the functions of the skeletal system The Skeleton • skeletal system – bones, joints, cartilages & ligaments • 2 divisions – axial longitudinal axis – appendicular limbs & girdles Overview • Functions – support internal framework; anchors soft organs – protection soft body organs (brain, vertebrae. rib cage) – movement skeletal muscles (tendons) – storage fat (internal cavities); Ca 2+ ; blood & bones, hormones; P – blood cell formation = hematopoiesis Classification • compact – dense, smooth & homogeneous • spongy – small needle-like pieces; open spaces • long – longer than wide; shaft w/ heads @ both ends; mostly compact; limbs EXCEPT wrist & ankle • short – cube-shape & spongy; sesamoid (form w/in tendons) • flat – thin, flat, curved; “sandwich” CSC; skull, ribs, sternum • irregular – don’t fit any category; vertebrae & hip Structure of a Long Bone • Gross Anatomy – diaphysis (shaft); length; compact; covered by periosteum =double layered CT that covers & nourishes the bone (Sharpey’s fibers secure periosteum to bone) – epiphyses =ends of long bone; thin layer of compact enclosing area w/ spongy – articular cartilage (instead of perisoteum) covers ext surface; glassy hyaline, smooth friction – epiphyseal line (remnant) & epiphyseal plate (hyaline cartilage) in growing bones; plates cause bone to lengthen; stops @ puberty (plates replaced by bone lines left) Structure of a Long Bone (con’t) • Gross Anatomy (con’t) – shaft stores fat; yellow marrow (medullary cavity); infants forms bc’s & red marrow; adults red marrow in cavities of spongy bone – bone markings (uneven surface) where tendons, muscles & ligaments were attached – 2 categories • 1. projections (processes) grow out from bone surface (T) • 2. depressions (cavities) indentations in the bone (F) except facet Bone Markings • projections (muscular & ligament attachment) – tuberosity -- tubercle – crest -- epicondyle – trochanter -- spine – line -- process • projections (form joints) – head -- condyle – facet -- ramus • depressions & openings (passage of BV & nerves) – meatus – sinus – fossa – groove – fissure – foramen Microscopic Anatomy • structure – nerves, bv’s nutrients & passageway for waste removal – osteocytes = mature bone cell – lacunae = depression/space in bone – lamallae =lacunae arr in concentric circles (Haversian) – central (Haversian) canals consist of – osteon (Haversian system) =system of interconnected canals Microscopic Anatomy (con’t) • structure (con’t) – canaliculi =small tube or canal that radiates outward from central canal to all lacunae – form a t-port system bone cells to nutrient source of hard bone matrix – perforating (Volkmann’s) canals run into compact bone @ right angles to the shaft Bone Formation, Growth & Remodeling • made of – cartilage & bone (adult) – bones replace cartilage • ossification – =bone formation – 1. hyaline cartilage covered w/ bone matrix by osteoblasts (=bone forming cells) – 2. hyaline cartilage digested medullary cavity – EXCEPT 2 regions: articular cartilage (AC) (bone ends) & epiphyseal plates (longitudinal growth) – new continuously formed on external face of AC – old touching internal face of AC & medullary cavity is broken replaced by bony matrix Bone Growth & Formation (con’t) • widen as they lengthen – osteoblasts (periosteum) add bone tissue to external face of diaphysis – osteoclasts in endosteum remove bone from inner face of diaphysis wall • appositional growth – bones diameter • growth hormone/sex hormone – long bone growth controlled by hormones – epiphyseal plate converted to bone Bone Growth & Formation (con’t) • dynamic – responds to s • 1. Ca levels in blood – LOW: parathyroid glands release PTH stimulates osteoclasts (bone destroying cells) to break matrix& release Ca ions into blood – HIGH: (hypercacemia) Ca deposited in matrix as hard, Ca salts • 2. pull of gravity on muscles on skeleton Bone Remodeling • essential – retain normalcy (proportions & strength) – thicken & forms large projections strength for muscular attachments – osteoblasts provide new matrix trapped osteocytes – atrophy (=loss of mass) – PTH determines IF/WHEN bone is broken OR needs more/fewer Ca ions in blood – stresses determine WHERE matrix is broken /formed Bone Fractures • fractures – closed (simple) clean break, no penetration – open (compound) break penetrates through skin – reduction realignment of broken ends • closed: bone ends coaxed into normal position • open: surgery requiring pins &/or wires cast – – – – – – comminuted breaks into fragments compression bone is crushed depressed broken portion pressed inward impacted broken ends forced into each other spiral twisting forces greenstick incomplete break Bone Repair 1. hematoma formation – bv rupture hematoma forms 2. fibrocartilage callus formation – – – fibrocartilage callus acts a bridge new capillary growth into hematoma AND phagocytes dispose of dead tissue form callus callus—cartilage or bony matrix, collagen fibers 3. bony callus formation – ostebolasts & osteoclasts move into area, fibrocartilage replaced by callus (spongy bone) 4. bone remodeling – callus remolded in response to mechanical stresses, forming a patch at fracture site Axial Skeleton • axial (80 bones) – longitudinal axis – 3 parts: • 1. skull • 2. vertebral column • 3. bony thorax Axial Skeleton • skull cranium – 8 large, flat bones – all single bones EXCEPT parietal & temporal (paired) – frontal bone (forehead) • bony projections under eyebrows • superior part of eye’s orbit Axial Skeleton • skull cranium • parietal bone paired bones superior & lateral walls of cranium; meet in midline @ sagittal suture and form coronal suture (frontal bone) • temporal bones inferior to parietal ; join @ squamous sutures • bone markings – – – – external auditory meatus (ear canal) styloid process (muscle attachment) zygomatic process bridge cheekbone mastoid process (mastoid sinuses; muscular attachment) – jugular foramen (passage of jugular vein) – carotid canal (internal carotid artery blood) Axial Skeleton (con’t) • skull cranium – occipital • • • • • most posterior bone forms floor & back wall of skull join parietal @ lambdoid suture foramen magnum spinal cord to connect w/ brain occipital condyles (lateral); rest on 1st vertebra Axial Skeleton (con’t) • skull cranium (con’t) – sphenoid • • • • butterfly shape; width of skull floor of cranial cavity small depression (sella turcica) holds pituitary gland foramen ovale (fibers of cranial nerve V to pass to chewing muscles) • sphenoid sinuses – ethmoid • irregular; anterior to sphenoid • roof of nasal cavity & part of medial orbital walls • crista galli projection (superior) – (outermost brain attaches here) • cribriform plates nerve fibers (olfactory receptors to reach brain) Axial Skeleton (con’t) • paranasal sinuses Axial Skeleton (con’t) • skull facial bones – maxillae upper jaw; all facial bones join palatine processes (hard palate) paranasal sinuses – palatine posterior to palatine bones; form posterior hard palate (lack of = cleft palate) – – – – – – zygomatic cheekbones; later walls of orbits lacrimal medial walls of each orbit; groove nasal rectangular bones form bridge of nose vomer single bone; medial line of nasal cavity septum inferior conchae thin, curved bones, lat walls (nasal) mandible lower jaw, joins temporal bones; freely movable; horizontal (chin) upright rami (connect w/ temporal) alveoli (sockets) – hyoid not part of skull; no articulations; base for tongue; attachment for muscles (talk & swallow) Axial Skeleton (con’t) • fetal skull – face small compared to cranium – skull is large compared to body length – hyaline cartilage not ossified • regions • • • • • fibrous membranes connecting bone =fontanels soft spots anterior fontanel (diamond shape) posterior fontanel (triangular shape; small) allows compression during birth Axial Skeleton (con’t) • vertebral column (spine) – extends from skull to pelvis – 26 irregular bones – ligaments create a flexible, curved structure – 33 vertebrae separated by intervertrebral discs (fibrocartilage) • 9 form sacrum (5) & coccyx (4) Axial Skeleton (con’t) • vertebrae – – – – body (centrum) disclike, bears weight vertebral arch formed laminae & pedicles form body vertebral foramen canal where spinal cord passes transverse processes 2 lat projections from vertebral arch – spinous process single projection from posterior of vertebral arch – superior & inferior articular processes paired; lateral to vertebral foramen; vertebra form joints w/ adjacent vertebrae Axial Skeleton (con’t) • cervical vertebrae – – – – C1-C7 1st & 2nd = atlas C1 (no body) & axis C2 (pivot) C2 odontoid process (dens) pivot point C3 C7 smallest & lightest Axial Skeleton (con’t) • thoracic vertebrae – T1-T12 – larger than cervical – heart-shaped w/ 2 articulating surfaces on either side • receive rib heads • lumbar – L1-L5 – blocklike; sturdiest Axial Skeleton (con’t) • sacrum – – – – – – – 5 fused vertebrae superiorly articulates w/ L5 alae articulate w/ hip bones sacroiliac joints forms posterior wall of pelvis median sacral crest dorsal sacral foramina sacral canal • coccyx – fusion of 3-5 irregular vertebrae – tailbone Axial Skeleton (con’t) • bony thorax – sternum, ribs, thoracic vertebrae – “thoracic cage” • sternum (breastbone) – – – – flat bone; attached to 1st 7 ribs fusion of manubrium, body, xiphoid process jugular notch (upper manubrium) sternal angle (manubrium & body meet – xiphisternal joint (sternal body & xiphoid process fuse) • ribs (12 pair) spaces intercostal muscles – true (pair 1-7) attach directly to sternum by costal cartilage – false (pair 8-12) attach indirectly or NO attachment (pair 11-12) floating ribs Appendicular Skeleton • appendicular skeleton – 126 bones – limbs, pectoral and pelvic girdles (attach limbs to axial skeleton) • shoulder (pectoral) girdle – 2 bones – clavicle & scapula Appendicular Skeleton • clavicle – collarbone – 2-curved bone – attaches to manubrium @ medial end & scapula laterally shoulder joint – holds arm away from thorax; prevents dislocation Appendicular Skeleton • scapulae – shoulder blade – triangular; wing-like – flattened body w/ 2 processes: • 1. acromion connects clavicle laterally @ acromioclavicular joint • 2. coracoid anchors some muscles of arm • glenoid cavity shallow socket that receives head of arm bone Appendicular Skeleton (con’t) • shoulder (con’t) – free moving • 1. sternoclavicular joint only point where shoulder girdle attaches to axial skeleton • 2. loose attachment of scapula mvmt back & forth against thorax (muscular) • 3. shallow glenoid cavity poorly reinforced ligaments flexible but easily dislocated! Appendicular Skeleton (con’t) • bones of upper limbs – 30 separate bones/limb – arm, forearm, hand • humerus – long bone – proximal head glenoid cavity – greater & lesser tubercles (muscle attachment) – deltoid tuberosity (deltoid muscle) – radial groove (groove for radial nerve) – distal trochlea & capitulum (forearm) coronoid fossa & olecranon fossa (ulna elbow flexes) ant post Appendicular Skeleton (con’t) • forearm – 2 bones • radius (anatomically/supine) – lateral thumb side – proximally & distally radioulnar joints & connected by interosseous membrane – head forms w/ capitulum (humerus) – radial tuberosity (biceps attach) • ulna – medial little finger side – proximal (a) coronoid process & (p) olecranon process sep by trochlear notch processes grip trochlea • radius & ulna (pronate) – distal radius medial to ulna Appendicular Skeleton (con’t) • hand – carpals, metacarpals, phalanges • carpal bones – 8 irregular bones in 2 rows carpus (wrist) ligaments • metacarpals – palm – 1 (thumb) to 5 (pinky) – fist knuckles • phalanges – fingers – 14: 3 proximal, mid & distal (thumb only prox & dist) Appendicular Skeleton (con’t) • pelvic girdle – 2 coxal bones {ossa coxae hip bones} and sacrum and coccyx form bony pelvis • bones – large, heavy attached to axial skeleton – sockets rec femur deep & heavy ligaments – function: ! bearing weight, protects repro organs & bladder Appendicular Skeleton (con’t) • 3 bones – ilium, ischium, pubis • 1. ilium – connects posteriorily w/ sacrum @ sacroiliac joint large flaring bone forms most of hip bone – alae are winglike portions upper edge iliac crest – ends anterior and posterior superior spine Appendicular Skeleton (con’t) • 2. ischium – – – – – “sitdown bone” inferior part of coxal bone ischial tuberosity rec’s weight when sitting ischial spine narrows outlet for pregnant women greater sciatic notch allows bv’s & sciatic to pass from post. pelvis into thigh Appendicular Skeleton (con’t) • acetabulum – fusion of ilium, ischium & pubis – rec’s head of femur • bony pelvis 2 regions – false pelvis (greater) • superior to true pelvis • medial to flares of ilia & pelvic brim – true pelvis (lesser) • surrounded by bone • female different than male Appendicular Skeleton (con’t) • 3. pubis – most anterior part of coxal bone – fusion of rami (pubic) anteriorly & ischium posteriorly forms a “bar of bone” enclosing the obturator = opening allows bv & nerves to pass into anterior thigh – pubic bones (each hip) fuse anteriorly pubic symphisis (= cartilaginous joint) Appendicular Skeleton (con’t) • female pelvis – – – – – larger & more circular shallower& bones; bones lighter & thinner ilia flare more (laterally) sacrum is shorter & less curved ischial spines are shorter & further apart outlet larger – pubic arch more rounded b/c angle of pubic arch is greater > 100° Appendicular Skeleton (con’t) • bones of lower limb – carry total body weight – 3 segments • 1. thigh (femur) – heaviest, strongest bone – proximal ball-like head, neck, greater & lesser trochanters sep (a) by intertrochanteric line (p) by intertrochanteric crest – gluteal tuberosity, trochanters, & intertrochanteric crest muscle attachment – head articulates w/ acetabulum – slants medially (knees align w/ center of gravity) females different (wider pelvis) – distal lateral & medial condyles articulate w/ tibia; sep by intercondylar notch; (a) patellar surface Appendicular Skeleton (con’t) • 2. leg (tibia & fibula) – tibia (shinbone) larger, more medial – proximal medial & lateral condyles (sep by intercondylar eminence) articulates w/ distal femurknee joint – patellar ligament attaches to tibial tuberosity (a) & (p) medial malleolus (process) bulge of ankle – anterior sharp ridge anterior crest – fibula forms joints (p & d); thin & sticklike – does NOT form knee joint – distal lateral malleolus (outer ankle) Appendicular Skeleton (con’t) • 3. foot – tarsals, metatarsals, phalnanges – functions: • 1. supports body weight • 2. lever that propels body (walk/run) – tarsus posterior half • 7 tarsal bones; 2 largest: – 1. calcaneus (heelbone) – 2. talus (ankle) bet calcaneus & tibia – metatarsals • 5 form sole of foot – phalanges • 14 (like hand, big toe only has 2) Appendicular Skeleton (con’t) • 3. foot (con’t) – arranged 3 strong arches: longitudinal (medial & lateral) transverse – ligaments (bond foot bones together) and tendons (muscle to bone) Skeletal System • joints – sites where 2 bones meet – articulations – vary in structure – classified acc’d to amt of mvmt allowed by joint • 1. structurally • 2. functionally – types • 1. synathroses • amphiarthroses • diarthroses Joints • functional types – 1. synarthroses (immovable) • no active mvmt • occur bet bones that are in close contact w/ one another • bones @ such joints are sep by a thin layer of fibrous CT • e.g. cranial bones (sutures) Joints • functional types (con’t) – 2. amphiarthroses (slightly) • fibrocartilage disks or ligaments • e.g. vertebrae covered by hyaline cartilage – 3. diarthroses (freely) • most joints • more complex structures • ends covered w. hyaline cartilage & held together by tubelike capsule fo dense fibrous tissue • flexibility varies Joints • structural types – 1. fibrous • fibrous tissue • sutures • syndesmoses connecting fibers are longer than those of sutures BUT joint has more ‘give’ • e.g. ends of tibia & fibula Joints (con’t) • structural types – 2. cartilaginous • bone ends are connected by cartilage • amphiarthrotic • e.g. pubis symphysis, intevertebral joints of spine – 3. synovial • sep by joint cavity w/ synovial fluid • 4 features – 1. articular cartilage (hyaline) covers bone ends – 2. fibrous articular capsule fibrous CT, capsule lined w/ synovial membrane – 3. joint cavity articular capsule encloses cavity containing synovial fluid – 4. reinforcing ligaments fibrous capsule reinforced w/ ligaments Joints (con’t) • structural types – 3. synovial • associations – bursae flat, fibrous sacs lined w/ synovial membrane & filled w/ synovial fluid; ligaments, muscles, skin tendons or bones rub togehter – tendon sheaths elongated bursa; wraps around a tendon that’s subjected to friction Synovial Joint Types • types – multi-axial • allow mvmts in all axes; including rotation; most free moving synovial joints – non-axial • = gliding does not involve rotation around any axis – uni-axial • = allow mvmt around 1 axis only – bi-axial • = mvmt around 2 axes Synovial Joint Types • hinge – convex end (cylindrical) of 1 bone articulates w/ concave end of another – uniaxial – ex: elbow joint, ankle joint, & joints bet phalanges of fingers • pivot – cylindrical surface of 1 bone fits into ring or sleeve of bone (& fibrous tissue & ligaments) – rotating bone turns around long axis – uniaxial – prx ends of tibia & fibula & ulna & radius • ball-and-socket joint – ball shaped head of 1 bone articulates w/ cup shaped socket of another – multiaxial – ex: shoulder & hip • condyloid joint – oval shaped articular condyle of 1 bone articulates w/ oval cavity of another – bone moves 1. side to side 2. back & forth, but NO axis – biaxial – ex: knuckle metacarpophalangeal joint • plane (gliding) – – – – art. surfaces are flat slipping, gliding mvmts allowed nonaxial ex: bones of wrist & ankle • saddle joints – each articular surface (concave & convex); surface of 1 fits into another – biaxial – ex: thumb carpometacarpal joint Joint Disorders • arthritis • • • • inflamed, swollen & painful joints different types but same symptoms acute = bacterial invasion; treated w/ antibiotics chronic – 1. rheumatoid – 2. osteoarthritis – 3. gout Joint disorders • 1. rheumatoid arthritis – most painful & crippling – synovial membrane of FMJ becomes inflamed, grows thicker – by damaged of articular cartilage on ends of bones & invasion of joint by fibrous CT – interferes w/ mvmt tissue ossifies where bones fuse together – auto immune = body’s own immune system destroys its own tissues Joint disorders • 2. osteoarthritis – degenerative – result of aging (most are 60+ years); athletes – art cartilage softens & disintegrates gradually surfaces become roughened joints sore & less mvmt is possible – OA most likely to affect joints that have rec’d greatest amt of use over years knees, vertebral column (lower) – “wear & tear” Joint disorders • 3. gout – produces uric acid (normal waste product) accumulates in blood & deposited as crystals in soft tissues esp. feet – untreated: bones fuse together & joint becomes immobilized – factors: undue stress, overweight, excessive alcohol intake