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Transcript
DNA and DNA Replication Step 3 • Breakout #1 The Origin of the Double Helix • Rosalind ___________________________ • X-‐ray photographs of ________________crystals • Research partner Maurice Wilkins • • Supervised Franklin and understood her work Watson & Crick • Used Franklin’s ________________________research and photographs to determine the structure of DNA • • undergo cell division Breakout #5 Accuracy and Repair • Replication is very ________________________ • One error in every ________________________________pairs of nucleotides • DNA is composed of two ______________________________________chains • Structure of DNA • DNA _________________________________have _______parts: • The number of ___________________and mutations are reduced by “proofreading enzymes” • like a spiral staircase Double ______________________ A mistake that results in a change in the nucleotide _____________________________ that wrap around each other to form a ____________________spiral, • ____________________________do occur • ___________________ The Double Helix Once the DNA is _________________________, the cell is ready to They detect errors and replace the ______________________ nucleotide with the _______________________ nucleotide • Doesn’t always work • Skin cancer Sugar molecule • ______________________________ • _____________________________ group • _____________________________ base Nitrogen ___________________ • Adenine = ______ • Guanine = ______ • Cytosine = ______ • Thymine = ______ Right – p. 1 Right – p. 3 Complementary Base Pairing • DNA nucleotides pair in _________________________ combinations • Base-‐pairing _______________________ • Cytosine & Guanine • • Adenine & Thymine • • ______________ ______________ Base pairs are connected to one another by _______________ ______________________ ____________________. Breakout #2 DNA Replication Taking a closer look at __________________________ Replication of DNA • ________________________________ • The process of copying DNA in the cell Step 1 • The __________________________________ of the __________________ • “_______________________________” DNA Breakout #3 Step 2 • The unzipped strands of DNA are used as ______________________________ • An _________________________________brings in free nucleotides to build the __________________________________________ daughter strands Breakout #4 Right – p. 2