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AP Bio CW Analysis Questions • In general what happened with Griffith’s experiment? • In general what happened with Avery, MacLeod, & McCarty’s experiment? • In general what happened with Hershey & Chase’s experiment? • What were Chargaff’s 2 findings from his research? • What did Franklin find from her research? • What did Watson & Crick find from their research? • What are the purines & pyrimidines? • What’s the difference between pyrimidines & purines? • What’s the difference between ribose & deoxyribose? • What makes up a nucleotide? • What makes up the sides or backbone of DNA? • What’s the difference between the 5’ & 3’ ends of DNA? • What are the base pairs for DNA? • What kind of bond forms between them? • How many hydrogen bonds form between A-T & C-G? • What is the model of replication that DNA follows? • When it comes to replicated DNA, how much of it is old & how much of it is new? • What’s the difference between the shape/structure of prokaryotic & eukaryotic DNA? • How many origins of replication does prokaryotic DNA have? • How about eukaryotic DNA? • What is the role of DNA helicase in replication? • What bonds does helicase break to unzip the DNA strands? • What is the enzyme called that’s responsible for adding on the new DNA bases? • What sort of bonds are formed when DNA polymerase adds new bases? • DNA polymerase can only add new bases to which end? • Replication is in the _____’ to _____’ direction • Why is there a leading & a lagging strand? • What’s needed to initiate replication once the strands have been unzipped? • What sort of bases are in the primer, RNA or DNA? • How many primer sequences are needed for the leading strand during replication, one or more than one? • How many primer sequences are needed for the lagging strand during replication, one or more than one? • When nucleotides are initially added to the replicated strand, how many phosphates do they have? • Replication of which side is faster, leading or lagging? • What enzyme helps “glue” the okazaki fragments together on the lagging strand? • True or False: Replication of the lagging strand is towards the replication fork • What are the repeated ends of chromosomes called that prevent uneven ends of strands? • What are the 2 parts to the cell cycle? • What are the 3 parts of interphase? • What happens during G1? • What happens during S? • What happens during G2? • What takes up more time for a cell, interphase or m phase? • True or False: There is more DNA present at the end of the S phase than at the beginning.