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I N T ROD UC I N G
Lyc-O-ProTM
Discover how years of clinical research on
our ingredients lead to the development of our
once a-day supplement blend.
Our standardized men’s health-grade
tomato extract, curcumin, zinc, and omega-3s blend:
Promotes prostate health and comfort*
Maintains healthy zinc levels in prostate tissue*
Supports hormonal balance as we age*
Supports healthy prostate cell growth
Who Should Take Lyc-O-ProTM ?
Our blend of standardized tomato extract, curcumin, zinc, and
omega-3s is the result of years of research, pre-clinical, and clinical
trials.*
• Continue to support their overall prostate health and comfort*
• Increase their zinc levels*
• Support their hormone levels*
Wellness You Can Feel.
The bioactive ingredients in Lycored Lyc-O-ProTM successfully
target and address key issues middle-aged men frequently face
with urinary function and overall prostate health.*
Men’s Health-Grade Tomato Extract: Our whole-food extract
contains five potent phytonutrients that have been optimized at
levels to encourage healthy prostate function.* This formula
includes our standardized, bioavailable lycopene.*
Zinc: This mineral has been found in high concentrations in
healthy prostate tissue.*
Curcumin: Our standardized complex of turmeric-derived
curcumin and its demethoxy derivatives has been shown to
support prostate health.* It’s also highly synergistic with our
standardized lycopene for even greater support.*
Black Pepper: Piperine is known to enhance the bioavailability
of curcumin.*
Omega-3s: These EPA and DHA essential fatty acids are known
to have a protective effect on prostate cells.*
Vitamin E: Our vitamin blend includes natural d-alpha
tocopherol.
Our Commitment To You
At Lycored, we believe that by combining natural nutrition,
rigorous clinical testing, and patent-protected processes and
ingredients we can offer real solutions supported by real
science.
Lyc-O-ProTM Takeaways
Combines curcumin and piperine to ensure optimal
absorption*
Once-a-day serving packaged in bioavailable
capsule promises long-term compliance
Proven synergy betweem the ingredients
Standardized ingredients blended
at effcacious levels*
Formulated using generally recognized
as safe (GRAS) ingredients
Combines our patent-protected carotenoid extract
with mineral, essential fatty acid, tocopherol, and
phytonutrient ingredients for proven effectiveness*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.
Earth-Made Ingredients.
Science-Driven Results.
We did extensive investigations into publicly available data
and conducted a number of trials to develop the proprietary
blend found in Lycored Lyc-O-ProTM. This analysis and
research effort included epidemiological results, in-vitro
mechanism-of-action studies, and formulation-specific
studies.
Prostate Health and Comfort Studies
Supplementation decreases PSA concentration1
Baseline
7.0
6 month
Serum PSA (µg/L)
BPH is a common condition in older men causing very
disturbing symptoms. Inflammation, oxidative stress as well
as androgenic activity in the prostate have been found to
play a key role in the etiology of BPH, Eventually leading to
increased cell proliferation. Enlarged prostate is associated
with urinary tract symptoms
The benefit of lycopene on PSA levels and prostate gland
enlargement 1
A six-month double-blind, randomized, placebo-controlled study
on men with benign prostate hyperplasia (BPH) measured PSA
levels (a well known clinical marker for determining the risk of
prostate-related conditions) and prostate gland size. Over the
course of six months, men taking a tomato lycopene
supplement blend experienced a reduction in PSA levels and
better control of prostate gland size.
6.0
5.0
4.0
Placebo
Lycopene
Reduction in PSA levels is following tomato lycopene
supplementation in men with BPK1
1. Schwartz, S. et al., 2008. Lycopene Inhibits Disease Progression in Patients with Benign Prostate Hyperplasia. J Nutr. 138(1): 49-53.
Ingredient Studies
The effects of our proprietary tomato extract and omega-3 on modulating prostate gene expression2
A double-blind, randomized placebo-controlled study tested the effect of tomato extract and omega-3s on gene
expression. Results found that the ingredients modulated two important regulatory pathways in prostate:
• Antioxidant defense mechanism (Nrf2)
• Androgen metabolism pathway
How our combined ingredients effect activate the antioxidant
defense mechanism
A recent study demonstrated a synergistic activation of the
antioxidant defense mechanism in prostate cells by a
combination of our ingredients: curcumin lycopene and
vitamin-E5. Activation of this transcription system is indicative
of prostate health.
Our ingredients synergistically activate the
antioxidant defense mechanism of prostate cells5
Triple
combination
500
ARE reporter activity
(Fold induction)
How our combined ingredients inhibit cell and prostate growth
An in-vitro study using a combination of lycopene and vitamin E
showed that the combination inhibited prostate cell proliferation3
An animal study combining lycopene and vitamin E showed
that the combination suppressed orthotopic growth of prostate
tumors by 73%.4
400
300
200
100
0
Vitamin E:
Curcumin:
Tomato Extract:
Double
combination
Effective
Synergy
Single
ingredients
+
+
+
+
+
+
+
+
+
+
+
+
Activation of antioxidant response element (ARE) in prostate cells
2. Magbanua, MJM. et al., Gene Expression and Biological Pathways in Tissue of Men with Prostate Cancer in a Randomized Clinical Trial of Lycopene and Fish Oil Supplementation. PLoS ONE. 6(9): e24004.
3. Pastori, M. et al., 1998. Lycopene in association with alpha-tocopherol inhibits at physiological concentrations proliferation of prostate carcinoma cells, Biochem Biophys Res Commun . 250: 582-5.
4. Limpens, J. et al., 2006. Combined Lycopene and Vitamin E Treatment Suppresses the Growth of PC-346C Human Prostate Cancer Cells in Nude Mice. J Nutr.136(5): 1287-1293.
5. Linnewiel-Hermoni, K. et al 2015. The anti-cancer effects of carotenoids and other phytonutrients residues in their combined activity. Archives of Biochemistry and Biophysics 572, 28–35
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases.
To learn more about Lyc-O-ProTM
and our entire range of products
email info@lycored or call 844-668-2483.
377 Crane Street, Orange, NJ, 07050
www.Lycored.com
Supplement Facts
Suggested Use: As a dietary supplement.
Take one soft gel daily, preferably with a meal.
Supplement Facts
Serving Size: 1 soft gel
Servings per container: 30
Amount Per Serving
% Daily Value
Vitamin E (as d-alpha-tocopherol) 22.4 IU
Zinc (as zinc oxide)
15 mg
75%
100%
Standardized Tomato Extract
225 mg
EPA (Eicosapentaenoic Acid)
90 mg
DHA (Docosahexaenoic Acid)
60 mg
Piperine
5 mg
(from Black Pepper Fruit Extract)
Curcuminoids
50 mg
(from Turmeric Rhizome Extract)
†
†
†
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Other Ingredients: Gelatin, Glycerin, Purified Water,
Caramel Color, Annatto Extract Color
Contains:Fish
Contains No: Peanuts, Tree Nuts, Shellfish, Eggs,
Milk, Wheat, Soy