Download Specific Immunity POGIL

Specific Immunity POGIL
Figure 1
Figure 1: Lymphocytes are the type of white blood cells essential for specific immunity. All
lymphocytes originate in the bone marrow. T cells mature in the thymus. Cytotoxic T cells
directly attack foreign cells. Helper T cells stimulate B cells. B cells convert into plasma cells
which release antibodies into the bloodstream. Some B cells differentiate into memory cells that
will respond to future invasions.
Figure 2: A phagocytic white blood cell called a macrophage identifies the foreign bodies’ cell
marker and gives this information to the T-cells to produce specific antibodies.
Discovery Questions: In using the two figures above, answer the following questions.
1.
2.
3.
What is the function of the lymphocytes?
What is the role of the:
a. T cell:
b. B cell:
c. Macrophage:
d. Memory cells:
Where are T cells produced? B cells produced?
Critical Thinking Questions: With the help of the figures above and below, answer the following
questions.
1. Does the shape of the antibody affect the immune response? Explain using reference to Figure
3.
2. How would a person who was infected with chicken pox develop an immunity?
Critical Thinking (Please read the following excerpt from:
http://chealth.canoe.ca/channel_condition_info_details.asp?disease_id=1&channel_id=2050&relation_i
d=38635 and answer the following questions)
The Facts on HIV/AIDS
AIDS (acquired immune deficiency syndrome) was first recognized in North America in the early
1980s. It is caused by a virus known as HIV (human immunodeficiency virus). HIV infection
has become a worldwide epidemic. About 33 million people are currently infected with
the virus.
In North America, the virus has infected nearly a million people and killed almost half a million
people to date. At the end of 2005, about 58,000 people in Canada had been infected with HIV,
and of these, an estimated 15,000 (or 27%) were unaware of their infection.
HIV is more common among certain populations at risk, such as people who inject illicit drugs,
and bisexual and gay men. HIV infections are also increasing among women, Aboriginal
peoples, and African and Caribbean communities.
1. What does AIDS stand for? And explain the severity of the AIDS epidemic amongst North
Americans.
2.
Illustrate a 3-paged pamphlet below that would emphasize the “workings” of the virus that caused
AIDS.