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Назва наукового напрямку (модуля): Семестр: 4 Krok. Microbiology, virology and immunology. Modul 1. Опис: Перелік питань: 1. A. * B. C. D. E. 2. A. * B. C. D. E. 3. A. * B. C. D. E. 4. A. * B. C. D. E. 5. A. * B. C. D. E. 6. A. * B. C. ?Quite often the cause of secondary immunodeficiency is an infection involvement, when the causative agents propagate directly in the cells of immune system and destroy it. The following diseases are characterized by: Infectious mononucleosis, AIDS Tuberculosis, mycobacteriosis Poliomyelitis, type A hepatitis Dysentery, cholera Q-febris, epidemic typhus In a patient with clinical signs of immunodeficiency the number and functional activity of T and B lymphocytes are not changed. Defect with dysfunction of antigen-presentation to the immunocompetent cells was found during investigation on the molecule level. Defect of what cells isMacrophages, the most probable? monocytes Т-lymphocytes, В-lymphocytes NK-cells Fibroblasts, Т-lymphocytes, В-lymphocytes 0-lymphocytes During surgical operation a blood transfusion was made. The blood must be checked to find antigens of some disease. What disease is expected to be found? Hepatitis B Virus Hepatitis A hepatitis Adenovirus Enterovirus Hepatitis E virus The donor who for a long time didn't donate the blood was investigated with ELISA. Anti-HBs antibodies were revealed. What does ELISA positive result in this case mean? After vaccination Acute hepatitis B Acute hepatitis C Chronic hepatitis В Chronic hepatitis С In order to speed up healing of a wound of oral mucosa a patient was prescribed a drug that is a thermostable protein occuring in tears, saliva, mother's milk as well as in a new-laid hen's egg. It is known that this protein is a factor of natural resistance of an organism. What is it called? Lysozyme Complement Interferon Interleukin Imanine Examination of a young man in the AIDS centre produced a positive result of immune-enzyme assay with HIV antigens. Patient's complaints about state of his health were absent. What can the positive result of immune-enzyme assay be evidence of? HIV infection Being ill with AIDS Being infected with HBV D. E. 7. A. * B. C. D. E. 8. A. * B. C. D. E. 9. A. * B. C. D. E. 10. A. * B. C. D. E. 11. A. * B. C. D. E. 12. A. * B. Having had AIDS recently HBV persistence A patient with clinical signs of encephalitis was delivered to the infectious diseases hospital. Anamnesis registers a tick bite. Hemagglutination-inhibition reaction helped to reveal antibodies to the causative agent of tick-borne encephalitis in the dilution 1:20 which is not diagnostic. What actions should the doctor take after he had got such result? To repeat the examination with serum taken 10 days later To examine the same serum To apply more sensitive reaction To repeat examination with another diagnosticum To deny diagnosis of tick-borne encephalitis A patient suffering from periodical attacks caused by inhalation of different flavoring substances was diagnosed with atopic bronchial asthma. IgE level was increased. This is typical for the following type of reactions: Anaphylactic reactions Cytotoxic reactions Immunocomplex reactions delayed-type hypersensitivity Autoimmune reactions A 10-year-old child had the mantoux tuberculin test administered. 48 hours later a papule up to 8 mm in diameter appeared on the site of the injection. What type of hypersensitivity reaction developed after the tuberculin injection? Type IV hypersensitivity reaction Arthus phenomenon Seroreaction Atopic reaction Type II hypersensitivity reaction A patient with clinical symptoms of immunodeficiency got immunological examinations. The doctor revealed absence of cells that form rosettes with sheep erythrocytes. What conclusion can be made according to the test result? Decrease of T-lymphocytes rate Decrease of B-lymphocytes rate Decrease of natural killer cell rate Decrease of complement system rate Insufficiency of effector cells of humoral immunity A virological laboratory obtained pathological material (nasal mucous discharges) taken from a patient with presumptive diagnosis "influenza". What rapid test will allow to reveal specific viral antigen in the material under examination? Direct and indirect immunofluorescence test Direct and indirect fluorescence immunoassay Hemagglutination inhibition test Radioimmunoassay ELISA A female patient underwent liver transplantation. 1,5 month after it her condition became worse because of reaction of transplant rejection. What factor of immune system plays the leading role in this reaction? T-killers Interleukin-1 C. D. E. 13. A. * B. C. D. E. 14. A. * B. C. D. E. Natural killers B-lymphocytes T-helpers A pregnant woman was registered in an antenatal clinic and underwent complex examination for a number of infections. Blood serum contained IgM to the rubella virus. What is this result indicative of? Of primary infection Of a chronic process The woman is healthy Of exacerbation of a chronic disease Of recurring infection with rubella virus Vomiting mass of a patient with cholera were delivered to the bacteriological laboratory. The material was used for preparing a "hanging drop" specimen. What type of microscopy will be applied for determination of motility of the causative agent for? Phase-contrast microscopy Electron microscopy Immune and electron microscopy Fluorescence microscopy Immersion microscopy