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Download Intermediary Metabolism-II SECTION A What are ketogenic amino
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Intermediary Metabolism-II SECTION A 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. What are ketogenic amino acids? What is transamination? Write a note on creatine? Give the structure of epinephrine. What are glucogenic amino acids? What are transminases? Give example. Write a note on creatinine. What is GABA? Explain the action of deaminase. How is pyruvate obtained from amino acids? Explain the significance of serotonin. How is GABA formed? How is α-KG obtained from amino acids? How is histamine synthesized? List out the significance of the same. How is creatinine converted to creatine? What are sphingomyelins? What are ganliosides? What is the tole of LCAT? What are Apolipoproteins? What are plasmalogens? Discuss the role of carnitine. What are chylomicrons? How are water insoluble triacylglycerol and cholesterol transported in the aqueous medium of blood? Expalin fatty acid synthetase enzyme complex components. What is the effect of dietary cholesterol on the cholesterol biosynthesis? When does acetyl CoA enter into ketogenesis? How is lipid stored in adipose tissue? How is fat synthesized? Explain the role of insulin on the mobilization of fat. How is Bile acid converted to bile salt? What are the excretory products of purine catabolism? Draw the nuclear skeleton of purine and indicate the sources of various atoms in it. Give any two inhibitors of nucleotide biosynthesis. How is purine base converted to purine nucleotide? Name any two inhibitor of pyrimidine biosynthesis and enumerate their importance. Define NAD. What is the role of FAD in metabolism. Draw the nuclear skeleton of pyrimidine. SECTION B 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. Explain decarboxylation of amino acids. Discuss the synthesis of epinephrine. How are dopamines synthesized? Explain the action of glutamate dehydrogenase. How is epinephrine formed? How are phosphoglycerides synthesized? Comment on the degradation of odd chain fatty acids. Discus about omega oxidation of fatty acids. How are phospholipids degraded? How is bile salt synthesized? Explain the action of lipase and the effect of hormone on its action. How are phospholipids interconverted? How is oleic acid degraded? Write about the inhibitors of nucleotide biosynthesis. Discus about salvage pathway. Discuss the regulation of pyrimidine nucleotides. Explain the degradative pathway of pyrimidine nucleotide. SECTION C 55. What is Transamination? Explain how amino acids are degraded by Transamination. 56. Explain how ammonia is detoxified to urea. 57. Write short notes on (i) serotonin (ii) GABA (iii) dopamine (iv) epinephrine. 58. Explain the mechanism of transamination reaction. 59. Explain the urea cycle. Explain the regulation of the pathway. 60. What are ketone bodies? How are they synthesized? 61. What is β-oxidation?How are fatty acids oxidized by β- oxidation? 62. Discus the biosynthesis of cholesterol regulation. 63. How is fatty acid synthesized? 64. How is pyrimidine nucleotide biosynthesis. Explain its regulation. 65. How is adenine synthesized? 66. Discuss the catabolism of purines and pyrimidines. 67. Define coenzyme derived from nucleotides