Download Week 4 met 2 kin 310

Kin 310 – Ex Met 2 Fuel Utilization and Neural – Endocrine Control
1. Describe the activation and translocation of free fatty acids into
skeletal muscle that is required prior to metabolism as fuel. (do not
include the regulation of translocation in your answer).
2. Describe the mobilization, circulation and uptake of free fatty
acids during exercise. Why do researchers measure FFA levels in
the blood during exercise?
3. Discuss the control of Free Fatty Acid translocation. Include a
brief discussion on the current understanding of the role of AMP.
4. Describe the intercellular lactate shuttle. Describe the
physiological benefits that are associated with lactate shuttles and
how an increase in mitochondrial LDH in type I fibers with training is
important?
5. Describe the intracellular lactate shuttle. Describe the
physiological benefits that are associated with lactate shuttles and
how an increase in mitochondrial LDH in type I fibers with training is
important?
6.
What are the sources of blood glucose?
7.
Differentiate between fed state and fasted state metabolism of
glucose in the liver. Including details of the changes in glucose
movement.
8.
Describe the control of Hepatic Glucose Production. What
changes do we observe with the transition from 55% to 82% VO2
max? Explain the significance and control mechanisms with this
transition from moderate to high intensity exercise.
9.
Summarize the overall process of gluconeogenesis in the liver.
10. Describe the influences over gluconeogenesis in the liver by
summarizing the control over changes cAMP between the fed and
fasted (or exercise) state.
11. Describe the detailed influence of a rise in cAMP on
gluconeogenesis in the liver.