Download DNA, Proteins and the Proteome - Guiding

Unit 3 Biology
DNA, Proteins and the Proteome
Guiding Questions
1. What does the central dogma of molecular biology outline?
2. What is the ultimate expression of this information?
3. The three parts of the central dogma are?
4. DNA and RNA are both what?
5. What do protein molecules do?
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How many nucleotides does the genetic code consist of?
What does the genetic code do?
How many bases code for one amino acid?
How many different amino acids are coded for by the genetic code?
How is mRNA generated?
11. The process of transcription involves?
12. The process of translation involves?
13. What is meant by the genetic code being universal?
14. What is meant by the genetic code being unambiguous?
15. What is meant by the genetic code being redundant?
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Where is DNA found?
What would happen if DNA ventured into the cytoplasm?
What is a mutation?
Why is damage to mRNA not important?
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What do genes code for?
How many genes in a typical human cell?
How many proteins in a typical human cell?
How can one gene produce different functional proteins?
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Can you sketch a simple diagram to illustrate the processes of transcription and translation?
What is the genome of an organism?
What is the function of the genome?
What is the proteome of an organism?
28. What do genomic projects involve?
29. What has the human genomic project provided doctors with?
30. What is the role of proteomics?
31. What will proteomics allow us to do?
32. What areas are proteomics currently being used to investigate?
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What is physiological genomics?
What can it be used to evaluate?
What does SNP stand for?
Why are physiological genomic studies involving SNPs important?
37. What are drugs?
38. Why would we like to tailor drugs to an individual?
39. What factors are important to consider when designing a drug?
40. What are two examples of successful designer drugs?
41. What does genetic engineering allow scientists to do?
42. Why would we want to combine the genes of two different organisms?
43. How can bacteria resist antibiotics?
44. What happens if a resistance gene for a particular antibiotic is present in a bacterial
population?
45. How can drug resistance be transferred between bacteria?
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What virus causes AIDS?
How is AIDS managed?
What do different HIV drugs target?
What does AZT target and why is it important?
50. What are the five different targets for designing new drugs to target HIV?