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GENETICS PEDIGREE CHARTS Pedigree charts show a record of the family of an individual. It can be used to study the transmission of a hereditary condition. It is particularly useful when there are large families and a good family record over several generations. You cannot make humans of different types breed together so pedigree charts provide one of the few ethical ways of studying human genetics. Today genetic engineering has new tools to offer doctors studying genetic diseases but a genetic counsellor will still use pedigree charts to help determine the distribution of a disease in an affected family. Symbols used in pedigree charts In a marriage with five children, two daughters and three sons. The second son is affected by the condition. Organising the pedigree chart Below is a pedigree chart of a family showing four generations. A total of 20 individuals. Generations are identified by Roman numerals. Individuals in each generation are identified by Arabic numerals numbered from the left. Therefore the affected individuals are II3, IV2 and IV3. Top of Page