Download BIO113 BIOLOGICAL SCIENCE CONCEPTS Unit 4 Disease and the

BIO113 BIOLOGICAL SCIENCE CONCEPTS
Unit 4 Disease and the Immune System
Chapter 17,
18, 19
Chapter 26
See lecture notes for specific pages
26.1, 26.3 (portions), 26.4, 26.5
The student will be able:
1. To examine the history of the development of the germ theory of disease
2. To define the following terms: pathogen, microbe, infectious agent, epidemic, plague
3. To provide examples of diseases transmitted by inhalation, body fluids, ingestion, and vectors
4. To determine why prions and viruses are not considered to be alive
5. To find commonalities between mad cow disease, and CJD, and Kuru in humans
6. To compare the normal brain prion protein, prp, with the abnormally folded prion and to associate
abnormal prions to the spongiform appearance of the infected brain
7. To examine the HIV including mode of infection, asymptomatic period, latency, symptoms, prevention
of transmission, treatment(s), global incidence, and AIDS
8. To compare Herpes viruses including those that cause oral and genital herpes, chicken pox and
shingles. To connect the biology of herpes viruses to herpes outbreaks
9. To provide rationale for why the United States no longer vaccinates for smallpox even though smallpox
can be deadly
10. To compare the past polio epidemics of the United States to current epidemics in other countries and to
determine why the World Health Organization has not been able to eradicate polio
11. To delve into the flu epidemics including the 1920 pandemic and the potential for future pandemics. To
follow the genetic rearrangement of flu virus that necessitates yearly vaccination
12. To examine the important roles of bacteria in the environment, bioremediation, food science, and
biotechnology
13. To understand the importance of antibiotic resistance in bacteria
14. To examine the Plague, or black death, and its transmission from flea to rats and humans and evaluate
the impact of the plague in the Middle Ages
15. To examine Lyme disease as an example of a bacterial infection transmitted through an intermediate
host
16. To examine malaria as a vector-borne disease caused by a protozoa (lecture notes)
17. To view a few parasites that cause human disease including round worm and tapeworm
18. To view the organs of the lymphatic system including red bone marrow, the thymus gland, spleen, and
lymph nodes
19. To distinguish between specific and nonspecific body defense systems and between self antigens,
foreign antigens, and antibodies
20. To differentiate between the roles of B lymphocytes and T lymphocytes in specific immunity
21. To apply the mechanism of antibody production by B cells to foreign antigens used in the vaccine
preparation to B-cell memory to disease protection
22. To contrast the role of the immune system in allergy and in autoimmune disease
23. To perform a simulation of blood typing, examine blood cells under the microscope, and investigate the
causes of anemia (lab)
24. To classify bacteria as rod-shaped, spherical, or spiral shaped species (lab).
25. To hypothesize about and investigate various environments for the presence of bacteria and fungus
and to test the efficacy of disinfectants, antiseptics, and antibiotics in the control of bacterial growth. To
communicate conclusions in written form (lab).