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Transcript
DNA, RNA, & Protein Synthesis
STRUCTURE:
•
The shape of DNA is a double helix or _____________________
•
DNA is made of nucleotide subunits that each consist of:
–
____________________________________________________
–
____________________________________________________
–
____________________________________________________
•
The “HANDRAILS” of the ladder are _____________ & ______________
•
The “STEPS” are the ______________ paired up.
•
The order of nucleotides creates a ____________
•
The code is _____________ for every living thing
•
Even _______________ have some differences in their codes
•
DNA is like the ___________________ in the cell “factory”.
•
It is located in the nucleus or ____________ of the cell.
•
It has specific ___________________ for every cell in your body
•
Only the “PAGES” or ___________ of the instructions needed by a particular cell
are actually used.
•
EX: THE DNA IN YOUR SKIN CELL HAS ALL OF THE
INSTRUCTIONS BUT THE ONLY PART THAT IS USED IS THE
INSTRUCTIONS FOR MAKING ________________.
DNA REPLICATION
•
WHEN NEW CELLS OR “FACTORIES” ARE NEEDED, THE DNA IS THE
____________ THING TO BE COPIED. IT OCCURS IN THE FOLLOWING
STEPS:
•
THE DNA LADDER _______________
•
_____________________________ FLOATING IN THE NUCLEUS PAIR UP
WITH THEIR COMPLIMENTS (A-T, C-G)
•
THIS CONTINUES IN SEVERAL POINTS ALONG THE LADDER UNTIL
__________________________
•
THE 2 NEW LADDERS EACH CONTAIN ONE _______________ AND ONE
____________________.
RNA Transcription and Translation
RNA STRUCTURE:
•
•
RNA HAS NUCLEOTIDE SUBUNITS
–
_________________
–
_________________
–
_________________
IT CONSISTS OF A ___________ STRAND (ONE SIDE OF A LADDER)
THERE ARE _______ TYPES OF RNA
FUNCTIONS:
•
TO CARRY A ____________ DIRECTION (RECIPE) TO THE RIBOSOMES
(______)
•
TO BRING THE AMINO ACIDS (INGREDIENTS) TO THE _______________
ACCORDING TO THE RECIPE (_____)
•
TO BIND THE ______________________ (INGREDIENTS) TOGETHER TO
MAKE PROTEIN-OR THE CANDY IN OUR FACTORY. (_____)
RNA TRANSCRIPTION – COPYING _____________ TO _______________
•
DNA “UNZIPS”- ONLY _____________________________
•
FREE NUCLEOTIDES PAIR WITH THEIR ___________________
•
ONLY A PORTION OF _________ SIDE OF THE DNA LADDER IS COPIED
•
THE MESSENGER RNA PEELS OFF THE DNA TEMPLATE AND LEAVES
THE NUCLEUS TO GO TO THE ________________
TRANSLATION: USING ___________ TO MAKE A __________________
•
Ribosome “reads” the recipe from the _______________
•
tRNA molecules bring the ________________ in the correct order according to
the codon
–
Every _____ bases codes for a particular amino acid
–
Look up the codon on page 303 of textbook (or table provided) to find
amino acid
–
Amino acid sequence determines ________________________
Summary:
DNA is found in ____________________
mRNA is made in the ___________________ from DNA template
mRNA carries the message to the _______________________
Protein is made using mRNA code like a “_________________” and amino acids as
“________________________________________”
Practice, Practice, Practice!!!
Translation:
Using mRNA to Make a Protein
A sequence of DNA contains the
code:
AAT TCC TGC
What would be the amino acid
sequence?
1. Transcribe the DNA:
UUA AGG ACG
2. Look up codons on table
3. Leu (leucine)
Arg (arginine)
Thr (threonine)
Mutations
•
Sometimes a mistake happens during replication:
•
The wrong __________ pairs up (___________________)
•
An extra base is __________ (_______________)
•
A base is __________________ ( ____________________)
If the mutation occurs in a portion of DNA that the cell ______________________,
then a _______________________________ is caused.
If the mutation occurs in a portion of DNA ___________
______________ by the
particular cell, then ___________________ __________________.