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HIGH SCHOOL BIOLOGY PACING GUIDE 2013-2014 3 days *The Characteristics of Life will be the basis of topics covered in class and the first topic reviewed/built upon from middle and elementary curriculum. Write BIOLOGY on the board Have students come up with the definition Group Poster Competition – All organisms have these in common (characteristics) Present poster (characteristics students came up with in groups) tell class how many characteristics the groups as a whole got correct then have them as individual groups figure out which ones were correct and see if they can come up with the missing ones Characteristics of Life Scramble turn this into notes if students wish Characteristics of Life PPT (as a review if needed) Eyewitness Life video and worksheet Characteristics of Life Play on words drawing “play on words” for classroom concept map (* characteristics and subtopics) Mystery Matter Lab Characteristics of Life Quiz (traditional or clicker or group) Characteristics of Life Review Packet Homework Assignment (for those not scoring well on quiz) Marty Martian Trial (Pre-AP or Top Level – depending on student maturity and ability) Virus Project (assessment) * Lab Safety, Lab Equipment, Technical Terminology, etc. will be covered within given topics versus having separate lessons Vocabulary: Biology Organism Scientific Method Observation o Inference o Fact Hypothesis Experiment o Constant o Control Group o Experimental Group o Independent Variable o Dependent Variable Data Conclusion Theory Law Ethics Metric System Broad Unit Topic Themes Estimated Time to Cover Organization of Life 2 weeks Contextual Language - - - - Variation Classification Taxonomy Binomial Nomenclature Taxon Species Genus Family Order Class Phylum Kingdom o Archaebacteria o Eubacteria o Protista o Fungi o Plantae o Animalia Domain o Archae o Eubacteria o Eukarya Virus Cladistics o Cladistic Analysis o Cladogram Phylogeny o Phylogenetic Tree Key Concepts Enduring Understandings Evolutionary Classification Life is organized at all levels from cells to biosphere. Evidence of Common Ancestry Modern classification systems are based upon biochemical and genetic evidence that indicates evolutionary relationships. Derived Characteristics Morphology Broadest to most specific Viruses are complex inert structures and their evolutionary relationship is still under consideration. Millions of different species of plants, animals, and microorganisms that live on Earth today are related by descent from common ancestors. Essential Questions What determines relationships in classification? What criteria do biologists use to classify organisms? How is the modern classification system and naming of organisms beneficial to all scientists? How does the evidence of evolution contribute to modern classification systems? Presentation Resources Broad Unit Topic Themes Estimated Time to Cover Comparing & Contrasting Life 3 days Contextual Language - Prokaryote Eukaryote Cyanobacteria Photoautotroph Thermoacidophiles Halophiles Methanogens Nitrogen-fixation Flagellum Capsule Nucleoid Capsule Endospore Pilus Lytic cycle Lysogenic Cycle Capsid Retrovirus Prion Bioluminescence Colony Contractile Vacuole Pellicle Plasmodium Protozoans Algae Pseudopod Cilia o Lichen o Chitin o Hyphae o Rhizoid o Yeast o Spore o Saprobe Key Concepts Prokaryote vs. Eukaryote Peptidoglycan/Cellulose/C hitin/Capsid Autotrophy vs. Heterotrophy Enduring Understandings All organisms and systems are organized from simple parts into complex systems that must maintain homeostasis in order to survive. Diverse organisms carry out common life processes differently. Essential Questions What are the similarities and differences among the six kingdoms of life? How are prokaryotic and eukaryotic organisms similar or different? How are unicellular and multi-cellular organisms similar or different? How are responses to conditions which threaten homeostasis the same and different for a variety of different cell types belonging to organisms in the same kingdom? How are responses to conditions which threaten homeostasis the same and different for similar cell types belonging to organisms representing different kingdoms of life? How do organisms (simple and complex) carry out life processes differently? Why do complex organisms have specialized structures to carry out life processes? Why would organisms in different kingdoms have similar or different characteristics? How would DNA extraction differ depending on the typical cell structure for a specified kingdom? Broad Unit Topic Themes Estimated Time to Cover 2 weeks Contextual Language - History of Life - - Biogenesis Spontaneous Generation Primordial Soup Microorganism Endosymbiosis Radiometric Dating o Half-Life Absolute Time o Relative o Law of Superposition Fossil Record Fossil Index Primitive Advanced Evolutionary Milestone Geologic Timescale Era: Precambrian Paleozoic Mesozoic Cenozoic Period: Quartenary Tertiary Cretaceous Jurassic Triassic Permian Devonian Silurian Ordovician Cambrian Epoch Cambrian Explosion Mass Extinction Key Concepts Evolutionary History Earliest cells & Multicellular Forms Endosymbionic Theory Molecular clock theory Enduring Understandings Molecular (biochemical) evidence supports anatomical (morphological) evidence from fossils about the sequence of descent. The great diversity of organisms is the result of more than 3.5 billion years of evolution that has filled every available niche with life forms. Evolution explains the number of different life forms we see, similarities in anatomy and chemistry, and the sequence of changes in fossils formed over more than a billion years. Essential Questions How can the history of organisms be explained in terms of Earth’s history, biodiversity and ancestry? How can common ancestry be analyzed through observation of similarities and differences among anatomy, biochemistry, and fossil changes in a diversity of organisms? What evidence indicates evolution has occurred? How has the evidence from evolution contributed to the organization of geologic time? How does fossil and biochemical evidence support evolutionary theory? How do similarities in the amino acid sequence of a protein among different species imply evolutionary relationships? What do fossil records show about changes in frequencies of phenotypes of inherited traits over time and the formation of new species? Broad Unit Topic Themes Estimated Time to Cover Perseverance of Life 2 weeks Contextual Language - Natural Selection Adaptation Regulation Fitness Biological Resistance Survival of the Fittest Evolution Derived Trait Homologous Structure Vestigial Structure Analogous Structures Speciation Gradualism Punctuated Equilibrium Adaptive Radiation Key Concepts Nature decides Only the strong survive to reproduce Enduring Understandings Essential Questions Environmental conditions affect organisms at cellular levels. What role does natural selection play in the changes in organisms over time? Organisms respond to internal changes and external stimuli to maintain homeostasis. How does natural selection influence evolution? Species evolve over time. How does comparative structure evidence support evolution? Evolution is a gradual process. Why is evolution by natural selection considered to be a mechanism for how life changes overtime? Evolution occurs in populations of organisms not individuals. How does natural selection drive the adaptations that increase the fitness of an organism for its environment? Natural selection is a primary factor in evolutionary change. How do interrelationships and interdependencies of organisms generate survivable adaptations? Change or die out Evolution is a consequence of the interactions of: 1. 2. 3. 4. 5. 6. the potential for a species to increase its numbers. the genetic variability of offspring due to mutations and recombination. a finite supply of resources required for life. the selection by the environment of those offspring better able to survive and leave offspring. Diversity among organisms is due to adaptations to changing environmental conditions. The adaptations of an organism enables the organism to be successful within an ecosystem through the action of natural selection. Favorable variations among individuals that increase the chance of survival tend to be passed onto successive generations. Broad Unit Topic Themes Estimated Time to Cover Perseverance of Life: Plant Adaptations 3 days + dissection Contextual Language - - - - - Stomata Guard Cells Turgor Pressure Nonvascular Plants o Alternation of Generations o Sporophyte o Gametophyte Vascular Plants o Xylem o Phloem Seed o Cotyledon o Seed Coat o Endosperm Pollination Gymnosperms o Cone Angiosperms o Pistil o Stamen Tropisms o Gravitropism o Phototropism o Photoperiodism o Thigmotropism Key Concepts Survival skills from primitive to advanced plants Enduring Understandings Diverse organisms carry out common life processes differently. Multi-cellular organisms are formed as highly organized arrangements of differentiated cells. Essential Questions How do plant adaptations influence their ability to survive stressful environmental conditions? Broad Unit Topic Themes Estimated Time to Cover Perseverance of Life: Animal Adaptations and Behavior 3 days + dissection Contextual Language - - - - - - - - Body Structure Anterior Posterior Dorsal Ventral Symmetry o Asymetrical o Bilateral o Radial Coelom Segmentation Cephalization Ectoderm Endoderm Mesoderm Appendages Tetrapod Bipedal Reproduction o Internal Fertilization o External Fertilization o Hermaphrodite o Sexual Selection (Courtship) Fertilization o Amnion o Placenta o Monotreme Skeleton o Invertebrate o Vertebrate o Endoskeleton o Exoskeleton o Cartilage o Bone Circulatory System o Open Circulatory System o Closed Circulatory System o Water Vascular System o Endotherm o Ectotherm Nervous System o Ganglia o Nerve Cord o Notochord o Chordate o Eye spot o Compound Eye o Binocular Vision Regeneration Respiratory System o Gills o Lungs o Diaphragm Excretory System o Nephron Integumentary/Lymphatic System o Glands o Hair Behavior o Hibernation o Migration o Foraging Behavior o Imprinting o Innate Behavior o Learned Behavior o Camouflage o Mimicry Key Concepts Survival skills from primitive to advanced animals Enduring Understandings Diverse organisms carry out common life processes differently. Multi-cellular organisms are formed as highly organized arrangements of differentiated cells. Essential Questions How have physical and behavioral adaptations affected animals’ ability to survive stressful environments? Broad Unit Topic Themes Estimated Time to Cover Chemistry of Life 2 weeks Contextual Language - - - - Monomer Polymer Calorie Macromolecule Carbohydrate o Monosaccharide o Disaccharide o Polysaccharide o Gluocose Protein o Amino Acid o Peptide o Enzyme Catalyst Substrate Activation Site Activation Energy Optimal Conditions Amylase Peptidase Lipase Lipid o Glycerol o Fatty Acid Nucleic Acid o Nucleotide o DNA o RNA o Nitrogen Base Key Concepts Monomer as related to Polymers Function of them Which make up cell parts Enduring Understandings All cells are composed of many different molecules that are organized into specialized structures that carry out cell functions. Most cell functions involve chemical reactions that utilize enzymes that either break down or synthesize compounds. Chemical bonds of food molecules contain energy that is released in the process of cellular respiration; the products are used to synthesize needed molecules. Enzymes are essential for metabolism in living things. Without enzymes, cell processes would occur too slowly for life. Enzymes work like a lock and key mechanism: the protein enzyme only fits and works with one type of substrate. Enzymes, biological catalysts, are proteins that are specific for the reactions they catalyze. Enzymes have optimal conditions (pH and temperature) for working. Essential Questions How are the four basic elements C,H,O,N bonded together to form the macromolecules? What is the function of the four major macromolecules (i.e., carbohydrates, proteins, lipids, nucleic acids). How is energy stored and released in food molecules? Describe the chemical composition and configuration of enzymes and discuss the factors that modify enzyme structure and/or function. How do enzymes function as catalysts? How does the lock and key mechanism of an enzyme work? How does the functioning of enzymes help cells/organisms do the following? a. maintain homeostasis b. cycle energy c. survive stressful conditions W h y are enzymes specific to certain substrates within organisms? How can enzymes act to decrease the energy input needed to form and break bonds in biochemical reactions? Basic Structure & Function of Life Broad Unit Topic Themes Estimated Time to Cover 3 days Contextual Language - - - - Organelle Cell Wall Cell Membrane o Plasma Membrane o Phospholipid Bilayer o Lipid Bilayer o Fluid Mosaic Model o Selectively Permeable o Transport Protein Cytoskeleton Cytoplasm Chloroplasts Nucleus o Nuclear Envelope o Nuclear Membrane o Nucleolus o Centrioles Lysosomes Ribosomes Cytoplasm Endoplasmic Reticulum o Rough o Smooth Golgi Apparatus (Body) o Vesicle Vacuole Mitochondria Flagellum Cilia Key Concepts Parts of a whole Subunit contributes to the welfare of the larger unit (organelle cell) Working cooperatively to maintain life Enduring Understandings Essential Questions Multi-cellular organisms are formed as highly organized arrangements of differentiated cells. How does cellular organization enable cells to carry out life processes? All cells are composed of many different molecules that are organized into specialized structures that carry out cell functions. How does the structural organization of a cell result in such a diversity of living things? Cells have particular structures that underlie their functions. Cellular processes of prokaryotic and eukaryotic cells are similar in-spite of their structural differences. Organisms carry out common life processes differently. How is the organization/function of organelles in a cell similar to the organization/function of departments in an industry? Why is cell differentiation necessary for the survival of multicellular organisms? Broad Unit Topic Themes Estimated Time to Cover Balance of Life 3 days Contextual Language Key Concepts Enduring Understandings Essential Questions - Homeostasis Survival and stability require that living things maintain biological balance at all levels. How do cells maintain equilibrium when environmental changes occur? Cells desire to be in an equilibrium state with the environment. How do organelles work together to maintain homeostasis in the cell? A cell can transport substances from location to location to maintain balance. How do organisms use diffusion and osmosis to maintain overall survival? - Passive Transport Active Transport Diffusion o Osmosis o Facilitated Diffusion o Isotonic Solution o Hypertonic Solution o Hypotonic Solution Concentration Gradient Turgor Pressure Endocytosis Exocytosis Phagocytosis Pinocytosis Plasmolysis Polarity Solute Solvent Solution Equilibrium Cell Transport Response to Environment Cells’ balance aids in an organism’s survival. The regulation of cell functions through the expression of genes (enzymes) allows cells to respond to the environment. Water is important for life. Water’s polarity makes it a good solvent and then helps to transport materials and maintain suitable temperatures for life. All organisms and systems are organized from simple parts into complex system that must maintain homeostasis in order to survive. Regardless of cell type, cellular components function together to maintain homeostasis. Organisms must use cell transport for survival at all levels of organization to maintain equilibrium. Broad Unit Topic Themes Estimated Time to Cover Contextual Language Key Concepts Enduring Understandings Essential Questions Energetics of Life 2 weels - Energy - Chemical Reaction Reactants Products Photosynthesis: o Chloroplast o Chlorophyll o Stomata, o Light-dependent Reaction o Light-independent Reaction Dark Reactions Calvin Cycle o Adenosine Triphosphate (ATP) o Adenosine Diphosphate (ADP) o Thylakoid o Stroma o Grana o NADP+ o NADPH o Transpiration - - Cellular Respiration: o Aerobic Respiration o Anaerobic Respiration o Lactic Acid Fermentation o Alcoholic Fermentation o Glycolysis o Kreb’s Cycle o Pyruvic Acid o Mitochondria o Electron Transport Chain o Metabolism Chemosynthesis: o Tube Worms o Chemosynthetic Bacteria o Hydrothermal Vents o Symbiosis o Hydrogen Sulfide Similarities and differences between photosynthesis, cellular respiration, and chemosynthesis. Reciprocal relationship of photosynthesis and cellular respiration. Alternatives to harsh environments Energy can be neither created nor destroyed but can be transformed from one form to another as it flows though organisms and ecosystems. Photosynthetic organisms use sunlight to combine inorganic molecules to form energy storing organic molecules and release oxygen that is vital to most living things. The process of photosynthesis provides the vital connection between the sun and the energy needs of living systems. Carbon and oxygen cycle through the processes of photosynthesis and respiration. Formulas of photosynthesis and cellular respiration are opposite of one another. What photosynthesis makes cellular respiration needs and what cellular respiration makes photosynthesis needs. Photosynthesis and cellular respiration are considered to be opposite reactions. Chemical bonds of food molecules contain energy that is released in the process of cellular respiration; the products are used to synthesize needed molecules. No light can reach the bottom of the ocean so organisms living their have to obtain energy through chemosynthesis. Chemosynthetic bacteria make glucose out of the chemicals of the earth so they are considered the producers of this environment – just as plants make glucose for other environments. How do organisms obtain and transform energy? How is energy transferred from sunlight to glucose to ATP? How is energy stored and released from food molecules? How are the processes of photosynthesis and respiration related? How do photosynthesis and respiration contribute to the Carbon cycle? How are plants and animals dependent upon one another to obtain or cycle matter? How does photosynthesis serve as the link between the inorganic and organic world? How are the processes of photosynthesis and respiration involved in the formation and breakdown of certain macromolecules? How is energy stored and released in living systems? How does the production of carbon dioxide in fermenting yeast show the cycling of energy in living systems? How are the products of cellular respiration used by photosynthetic organisms? Connections of Life 2 weeks - - - - - - - - - Thermodynamics Autotroph o Photosynthesizer o Chemosynthesizer Heterotroph o Carnivore o Herbivore o Omnivore o Detritivore Habitat Population Community Ecosystem Biome Biosphere Food Chain Food Web Ecological Hierarchy Ecological Pyramid: Trophic Level Biomass Pyramid Energy Pyramid Population Pyramid Symbiosis o Mutualism o Commensalism o Parasitism Nutrient Nutrient Cycles Biogeochemical Cycle Nitrogen Cycle: Nitrogen Fixation Denitrification o Water Cycle o Carbon Cycle o Phosphorus Cycle Niche o Producer o Predator o Prey o Decomposer Abiotic Biotic Limiting Factor o Competition o Resource o Pollution o Carrying Capacity Density-Independent Factor Density-Dependent Factor Population Growth Rate Logistic Growth Model Dispersion Emigration Immigration Population Density Exponential Growth Model Biodiversity Species Diversity Genetic Diversity Ecosystem Diversity Biological Magnification Ecological Succession Primary Succession: Pioneer Species Climax Community o Secondary Succession Endemic Extinction Habitat Fragmentation Invasive species Natural Resource Nonrenewable Resource Interdependence Patterns of ecological organization are similar to those of cells and organisms. Cycles in Nature Energy Transference Factors that affect populations Biodiversity Energy can neither be created nor destroyed but can be transformed from one from to another as it flows through organisms and ecosystems. How do energy and matter move through the ecosystem? How is ecosystem stability achieved and maintained? How do community interactions maintain stability in an ecosystem? How do biotic and abiotic factors shape an ecosystem and determine the communities that will be successful in it? How is energy transferred in an ecosystem? Energy flows through ecosystems in one direction from photosynthetic organisms to herbivores to carnivores and decomposers. Everything is connected from the biosphere to the atom. How is the biosphere like a cell in that both are composed of parts that work together to make the whole? How do the 1st & 2nd Laws of Thermodynamics apply to energy transfer in an ecosystem? How do organisms in a food chain & food web relate? The atoms and molecules on earth cycle among the living and nonliving components of the biosphere. SB4b Describe how the three ecological pyramids represent trophic levels in ecosystems. Slight changes can cause drastic changes. Describe how nutrients move through the biotic and abiotic parts of an ecosystem. Explain why decomposers are important in ecosystems. Describe the importance of nutrients to living organisms. How does energy flow through an ecosystem? Organisms both cooperate and compete in ecosystems Organisms are interdependent on each other and their environment. How much energy is available to be transferred to each level of a food chain consisting of grasses, grasshoppers, finches, and a hawk? Why is the amount of energy not the same in all trophic levels in a food chain? Why are there a limited number of trophic levels in a food chain? The distribution and abundance of organisms in populations and ecosystems are limited by the availability of matter and energy and the ability of the ecosystem to recycle materials. The interrelationships and interdependencies of organisms may generate ecosystems that are stable for hundreds or thousands of years. Compare the biogeochemical cycles of nutrients. How is a habitat different from a niche? What is an example of a habitat and an individual’s niche in that habitat? What are some abiotic factors that limit plant growth? What are some biotic factors that limit plant growth? How do adaptations affect organisms’ ability to survive stressful environmental conditions? Why do limiting factors have a lesser impact on humans than for most other organisms? The total energy found in organisms from one trophic level in a food chain is not available to organisms in the next trophic level as only a portion of energy consumed is stored as organic matter; the rest is utilized in metabolic processes or transformed into heat. Summarize the concepts of carrying capacity and limiting factors. Ecosystems result from dynamic relationships between organisms and their environment. How is energy transferred in an ecosystem? Living organisms have the capacity to produce populations of infinite size but are limited as environments and resources are finite Why does energy only flow in one direction in an ecosystem? Human activities and natural phenomena disrupt the homeostatic nature of the environment How can the human race help prevent causing negative changes within the ecosystems of the biosphere? Compare and contrast logistic and exponential growth models. Compare and contrast species diversity and genetic diversity. Explain why ecosystem diversity results in species diversity in a healthy biosphere. Why is preserving biodiversity important? How do plants and animals depend on each other based on energy flow in ecosystems? How is a food web different from a food chain? What are some changes that occur in an ecosystem caused by the activities of humans? How do human activities interrupt the stability of ecosystems? Patterns of evolution vary and can be impacted by human Activities What are the components of an ecosystem? How does human activity impact an ecosystem? How do natural selection pressures shape population growth curves? Human activities and natural phenomena often disrupt the environment causing changes in the population dynamics and steady state balances of the biotic and abiotic factors in the environment. How do ecosystems influence the relationships among organisms in changing environments? Broad Unit Topic Themes Contextual Language Growth & Reproduction of Life 3 days - - Cell Cycle Stem Cell Asexual Reproduction o Cell Growth Mitosis Diploid Somatic Cell Autosome o Budding o Vegetative Propagation o Regeneration o Binary Fission o Spore Formation o Cancer o Carcinogen Sexual Reproduction Meiosis Haploid Gametes o Conjugation o Fertilization Key Concepts Advantages and Disadvantages of Asexual and Sexual Reproduction Genetic Diversity Enduring Understandings Essential Questions Organisms must be able to grow and reproduce to ensure species survival. If every living organism is made of cells, why do we all look different? In the development of multi-cellular organisms, the progeny from a single cell forms an embryo in which the cells multiply and differentiate to form the many specialized cells, tissues, and organs that comprise the final organism. What are the advantages of sexual reproduction over asexual reproduction in terms of genetic variability and the population diversity which results? Sexual reproduction leads to diversity to help species survive bad environments, whereas asexual reproduction does not. Asexual reproduction is advantageous for producing large numbers of offspring to ensure the propagation of the species. Cells in sexually reproducing organisms contain two copies of each chromosome; therefore, two copies of each gene explain many features of heredity such as how variations that are hidden in one generation can be expressed in the next. Cells undergo programmed cell growth, division and death. Certain factors promote and control these processes. Eukaryotic cells undergo a more complex cell division than prokaryotes. The reproductive patterns of organisms are affected by environmental conditions. What are the evolutionary advantages of the maintenance of methods of asexual reproduction, even within plant species which are capable of sexual reproduction? How does natural selection help to maintain the diversity of plants so that plants can continue to use both asexual and sexual reproduction to survive? Broad Unit Topic Themes Estimated Time to Cover Codes of Life 3 days Contextual Language - - Deoxyribonucleic Acid (DNA) o Double Helix o Nucleotide o Base Pairing Rule o Replication o DNA Polymerase o Hydrogen Bond Ribonucleic Acid (RNA) o Ribosomal RNA (rRNA) o Messenger RNA (mRNA) o Transfer RNA (tRNA), o RNA Polymerase o Codon o Anticodon o Transcription o Translation Key Concepts DNA and RNA are different Importance of both DNA and RNA Enduring Understandings The instructions for specifying the characteristics of an organism are carried in DNA, a large polymer formed from the subunits ATCG, located in the cell(s) of that organism. Essential Questions How does DNA code for living organisms? How can a change in the sequence of DNA affect the type of protein that is coded? Why would two different species have similar DNA and yet have different traits? Why are the processes of translation and transcription crucial to biological function in an organism? Broad Unit Topic Themes Estimated Time to Cover Heredity of Life 2 weeks Contextual Language - - Chromosome Sex Chromosomes Genes Traits Inheritance Allele Punnett Square Probability Phenotype Genotype Homozygous o True breed Heterozygous o Hybrid Mendel’s Laws Law of Dominance: Dominant Recessive o Law of Segregation Law of Independent Assortment: Homologous Chromosome Crossing Over Polyploidy Polygenic Trait Co-dominance Incomplete Dominance Multiple Alleles Key Concepts Trait Inheritance Enduring Understandings Using the DNA code, cells manufacture needed proteins that determine an organism’s phenotype. Mendel Hereditary information, coded by DNA, is passed down from generation to generation in a predictable way. Cells in sexually reproducing organisms contain two copies of each chromosome; therefore, two copies of each gene explain many features of heredity such as how variations that are hidden in one generation (Law of Dominance) can be expressed in the next (Law of Segregation). Essential Questions What is the relationship between genetics and evolutionary adaptations? How do the laws of inheritance influence organisms’ genetic variability? What are the effects of meiosis on genetic variability? How is the basis of the principle of segregation a mechanism of genetic variability? How does independent assortment correlate with reproductive variability? By what mechanisms is heredity transmitted from generation to generation? How can the frequency of a gene in a population be determined? What conditions could cause changes in the frequency of alleles in a population? How could you trace the transmission of genetic traits through successive generations of a family? Why do Mendel's laws and the Hardy-Weinberg principle provide biologists with an avenue for prediction of trends in inheritance and evolution over time? How can a change in DNA in one organism affect future generations of a population? What is the relationship between natural selection and allelic frequencies in a population? Broad Unit Topic Themes Estimated Time to Cover Alterations in Life 3 days Contextual Language - Mutation Mutagen Biological Magnification Pedigree Karyotype Genetic Disease (Trisomy) Sex Linked Trait Carrier Restriction Enzyme Gene Mutation Chromosome Mutation o Substitution o Frameshift o Nondisjunction o Translocation o Deletion o Insertion Key Concepts Change is not always bad Mutations can be linked to the health of the environment Enduring Understandings Essential Questions Changes in DNA occur spontaneously at low rates; some of these changes make no difference to the organism whereas others can change cells and organisms. What are some of the major causes of genetic mutations that lead to diseases? Favorable variations among individuals that increase the chance of survival tend to be passed on to successive generations. What progress has been made in the research of gene therapy? The reproductive patterns of organisms are affected by environmental conditions. Mutations can occur in both autosomal and sex chromosomes and have various causes, but only mutations in germ cells can contribute to the variation that changes an organism’s offspring. What treatments can be offered to alleviate the symptoms of a genetic disorder? How are Mendel's laws demonstrated by the occurrence of genetic diseases? Was your investigated syndrome or disease an autosomal mutation or a mutation that occurred in the germ cells? Explain your answer using Mendel's laws of inheritance. Why do dental assistants take care to cover your reproductive organs while X-raying your teeth without shielding your head, neck or arms? How can mutation and meiosis result in a new trait appearing in an organism? How do human activities alter mutation rate in populations of organisms? How can mutation adversely affect a population? Enhance the viability of a population? How can adaptations and mutations in a population become more prevalent by processes such as natural selection? Biotechnology Broad Unit Topic Themes Estimated Time to Cover 3 days Contextual Language Key Concepts Enduring Understandings Essential Questions - Genetic technology is expanding DNA offers important information about life that can provide technological advances in forensics, medicine, and agriculture. How has genetics influenced the development of genetically modified organisms? Genetic Engineering Genetic Recombinant Biological Resistance Cloning Selective Breeding Transgenic Organism DNA Fingerprinting PCR Gel Electrophoresis Bioethics Genome Gene Therapy Inbreeding Plasmid Recombinant DNA Restriction Enzyme Selective Breeding The development and use of technologies may lead to social, moral, ethical, and legal issues. Biotechnology provides potential solutions to problems or improvements to products by applying modern biological techniques to many environmental and health issues in our world. Biotechnology may have significant social, environmental or ethical concerns which must be considered and addressed. The development of new biotechnical solutions is a complicated and extensive process and requires the input of many disciplines, people, and consideration of many issues. What impact will advances in DNA biotechnology have on your life? How can the differences in each organism’s genetic material be used to isolate/identify specific organisms? What are some uses of DNA fingerprinting? How can biotechnology be used to solve problems and/or resolve current environmental and health issues? How can a new or improved biotechnology product be marketed? What role does DNA have in storing and transmitting cellular information? What impact would altering a segment of DNA have on cell function? What types of DNA technology are being used to treat known genetic diseases? How has the Human Genome Project contributed to our knowledge of genetic diseases? Why have gene therapies and their development been debated among members of the medical community over the past few years? What impact do lethal genetic recombinations have on populations? Pres Students will understand importance of epidemiology, disease progression, spread and prevention. They will further understand how antigens and antibodies work and that there are certain tests that can be used to detect the presence and track the spread of some infectious diseases. Essential Question(s): 1. What types of microorganisms can cause an epidemic? 2. How can an infectious disease be detected and tracked? 3. How can we prevent the spread of infectious diseases such as Hepatitis B? Vocabulary Words: Reagents Antigen Immunity Antibody Epidemiology Vaccine Antibiotic