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AP Biology – Chapter 5 (Worksheet) Lookabaugh – Campbell Seventh Edition Objectives: The role of dehydration synthesis in the formation of organic compounds and hydrolysis in the digestion of organic compounds How to recognize the four biologically important organic compounds (carbohydrates, lipids, proteins, and nucleic acids) by their structural formulas The cellular functions of all four organic compounds. The four structural levels that proteins can go through to reach their final shape(conformation) and the denaturing impact that heat and pH can have on protein structure Concept: Most macromolecules are polymers, built from monomers 1. ________________ are long chains molecules made of repeating subunits called monomers. Examples: Starch is composed of _________________ monomers and proteins are composed of ___________ ____________ monomers. LIPIDS are not polymers. 2. Condensation or __________________ reactions occur to create molecules from monomers. This requires the removal of _____________. Example: C6H12O6 + C6H12O6 → C12H22O11 + H2O 3. ________________ occurs when water is added to split large molecules. This occurs in the reverse of the above reaction. Concept: Carbohydrates serve as fuel and building material 4. Carbohydrates include both ____________ sugars like(glucose, ____________ and galactose) and are polymers such as starch. All carbohydrates exist in the same ratio which is: _________ C _________ H and _________ O. 5. __________________ are monomers of carbohydrates. Examples include glucose and ____________ which is in RNA. 6. __________________ are polymers of monosaccharides. Examples are starch, _______________(found in plant walls), and glycogen(found in _______________ and is how sugar is stored.) 7. Two functions of polysaccharides are energy _______________ and _______________ support. Energy Storage Polysaccharides ___________________ is a storage polysaccharide found in plants (e.g., potatoes) __________________ is a storage polysaccharide in animals, vertebrate muscle and ______________ cells. Structural Support Polysaccharides __________________ is a major component of plant cell walls. ______________ is found in the exoskeleton of arthropods, such as lobsters and insects and the cell walls of ______________. It gives cockroaches their _____________ sound. 1 Concept: Lipids are a diverse group of hydrophobic molecules 8. Lipids are all ________________________. They aren’t polymers, as they are assembled from a variety of components. Examples include waxes, ____________, fats and _______________. 9. Fats also known as ________________________ are made up of one ________________ molecule and three ______________ acid molecules. 10. Fatty acids include _________________ chains of variable lengths. These chains are nonpolar and therefore ______________________. Saturated fatty acids: have _________ double bonds between carbons tend to pack solidly at ___________ temperature are linked to ____________________ disease are commonly produced by _________________ examples are _______________ and lard ________________ fatty acids: Have some _______________ carbon bonds, this results in __________ in the molecule Tend to be _____________ at room temperature Are commonly produced by ______________ Examples include are corn oil and _________ oil 11. Phospholipids make up cell __________________. They Have a __________ backbone (head), which is hydro_____________. Have two fatty acid ____________ and are hydro_______________. 2 Are arranged in a ______________________ forming a cell membrane, with the _________________ heads pointing toward the watery cytosol or _________ cellular environmnent, and ________________ tails sandwiched between. 12. ______________________ are made up of four rings that are fused together. ___________________ is a steroid and is a common component of cell __________________. Estrogen and testosterone are steroid ___________________. ________________ ______________________ ________________ ________________ Concept: Proteins have many structures, resulting in a wide range of functions 13. Proteins are ________________ made up of amino acid ____________________. 14. Amino acids contain a central carbon bonded to a __________________ group, an amino group, a _____________ atom and an R group (variable group or side chain.) 15. _____________ bonds link amino acids. They are formed by __________________ synthesis. The “____________________” of the protein depends on the order and ____________ of amino acids. 16. There are four levels of protein structure: _____________________ structure is the unique sequence of amino acids that are joined. _____________________ structure refers to one of “two possible” 3-Dimensional shapes that are results of _______________ bonding. Alpha helix ________ is a coiled shape. _________ pleated sheet β is an _____________ shape. Tertiary structure results in a complex _______________ shape, due interactions between R-groups, such as hydrophobic interactions, van____________ interactions, ______________ bonds and disulfide bridges. Globular proteins such as ___________________ are held in position by these R-groups. ________________ structure refers to the association of two or more ____________________ chains into one large protein. Hemoglobin is a globular protein with this structure, and is composed of _______ chains. 17. Protein shape is crucial to protein _________________. When a protein does NOT fold properly, it will not work correctly. This can be a result of a ___________________ amino acid substitution. Example: Abnormal hemoglobin formation which results in _____________________ disease. 3 18. _____________________ are protein molecules that assist in the proper folding of proteins within cells. They provide an isolating environment in which a polypeptide chain may attain final __________________. 19. ________________________ occurs when a protein loses its shape and ability to function properly due to _______________, change in _______ or some other disturbance. Concept: Nucleic acids store and transmit hereditary information 20. DNA (______________________________________), and RNA(____________________________), are the two nucleic acids. Their monomers are _______________ acids. 21. Nucleotides are made up of three parts: Nitrogenous base They are: ____________,______________ _____________ _________________ _______________. A pentose (_______ carbon) sugar. DNA has _______________ and RNA has________________ _____________________ group 22. DNA is the molecule of ______________________. It is a double-stranded ______________. Its nucleotides are ______________________________________________________. They always bind _______________ + ________________ and _____________ + ____________ 23. RNA is _______________ stranded. Its nucleotides are ______________, _______________, _____________ & ______________ It does NOT have ________________________ Fill in the chart with the missing information: Macromolecule Carbohydrates Monomer/Component Lipids Fatty acids, ______________ Amino acids Nucleic Acids Examples Functions Sugar, starch, Energy, energy storage, __________,______________ structure Important energy source, _____________ Movement 4 ___________ DNA, ___________ Heredity, code for proteins