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Genes and DNA Unit Test Figure 1 1. 1? What will be the result of the mutation in Figure a. b. the organism will die it will have no affect on protein c. d. only one amino acid will change nearly every amino acid in the protein will be changed function 2. What type of mutation has occurred in Figure 1? a. protein b. frame shift c. point mutation d. lethal Figure 2 3. Which of the structures in Figure 2 are composed of RNA? a. III and IV b. I and V c. II and IV d. III and V 4. In which part of the cell does this process shown in Figure 2 take place? a. in the nucleus b. on the chromosome c. in food vacuoles d. at the ribosomes 5. Structure III a. b. c. d. gene in Figure 2 represents a(n) _____. codon amino acid DNA molecule 6. Structure I in Figure 2 represents a(n) _____. a. codon b. amino acid c. DNA molecule d. anticodon 7. In Eukaryotes, structure II in Figure 2 was built in the: a. at the ribosomes b. in the mitochondria c. in the rough endoplasmic reticulum d. in the nucleus 8. The process illustrated in Figure 2 is called _____. a. transcription b. replication c. translation d. monoploidy Table 1 9. Using Table 1 to translate the mRNA sequence AUGGCAUACAAGUUCGACGUAG results in the following biological sequence: a. Ile-Ala-Tyr-Asp-Tyr-Arg b. Met-Ala-Tyr-Lys-Phe-Asp c. UACCGUAUGUUCAAGCUGCAUG d. Met-Ala Figure 3 10. Which structure shown in Figure 3 would attract a free cytosine nucleotide? a. B b. A c. D d. C 11. Which structure shown in Figure 3 is a pyrimidine? a. A b. C c. D d. B 12. Which structure shown in Figure 3 does not contain a nitrogenous base? a. B b. C c. D d. A 13. Which structure shown in Figure 3 is part of the backbone of the DNA double helix? a. C b. B c. A d. D 14. Which structure shown in Figure 3 is part of the interior of the DNA double helix? a. D b. A and D c. A and B e. C 15. Which of these chromosomal mutation diagrams shows insertion mutation? a. b. c. d. Table 2 16. The data in Table 2 provide evidence for which fact about DNA: a. C and T form base pairs b. the backbone of DNA is only stable with a certain base composition c. C and G form base pairs d. the percentage of each base is the same for all organisms 17. Which of these statements is NOT true? a. While chromosomal mutations occur in all living organisms, scientists see them most commonly in plants rather than animals. b. An organism that has been affected by a chromosomal mutation and lives to maturity is often sterile. c. The reason that chromosomal mutations usually do not get passed along to future generation is that an affected zygote usually dies. d. Asbestos is not considered a chemical mutagen responsible for chromosomal mutations. 18. Thymine and cytosine are also called __________. a. isotopes b. purines c. viruses d. pyrimidines 19. Which one of the following nucleotide pair bonds would be found in a DNA molecule? a. cytosine-uracil b. adenine-cytosine c. adenine-guanine d. guanine-cytosine 20. Which of these sequences correctly describes how DNA is copied? a. replication—bonding of bases— separation of strands—base pairing b. replication—bonding of bases—base pairing—separation of strands c. separation of strands —base pairing— bonding of bases—replication d. separation of strands—bonding of bases—replication—base pairing 21. __________ is a change in a single base pair in DNA. a. chromosomal mutation b. point mutation c. frameshift mutation d. gamma mutation 22. Which of these correctly matches with the nitrogenous base adenine in DNA? a. guanine b. thymine c. cytosine d. adenine 23. What is an intron? a. a long, noncoding nucleotide sequence in genes b. part of the translation process c. an amino acid d. a codon 24. The process where enzymes make an RNA copy of a portion of a DNA strand is called __________. a. acid creation b. replication c. transcription d. helix creation 25. AUG is __________, while UAA is __________. a. a stop codon—a start codon b. a start codon—a stop codon c. transfer RNA—messenger RNA d. a ribosome—a protein 26. Which of the following is one difference between RNA and DNA? a. RNA contains uracil, while DNA contains thymine. b. RNA and DNA are the same thing. c. RNA is double stranded, and DNA is single stranded. d. RNA's sugar is deoxyribose, while DNA's sugar is ribose. 27. Which of these is usually NOT considered a mutagen? a. nuclear radiation b. ultraviolet light c. low temperatures d. formaldehyde 28. Which of these DNA strands would the DNA strand A-T-G-C-C-G-T-T match to? a. G-C-A-T-T-A-C-C b. C-G-T-A-A-T-G-G c. T-A-C-G-G-C-A-A d. T-T-G-C-C-G-T-A 29. Which nitrogenous base does uracil pair with in RNA? a. guanine b. cytosine c. thymine d. adenine Figure 4 30. Which of the models in Figure 4 is an accurate representation of DNA replication? a. conservative replication b. dispersive replication c. semiconservative replication d. none of the above 31. The removal of introns from eukaryotic mRNA before translation is called? a. splicing b. transcription c. RNA editing d. intron excision In 1952, Hershey and Chase radioactively labeled viruses that contained only protein and DNA, before infecting bacteria with the viruses. They created two different types of viruses, one type in which only the DNA was radioactively labeled and one type in which only the protein was radioactively labeled. Upon infection only the bacteria that was infected by the viruses with radioactive DNA became radioactive, producing radioactive new viruses. 32. This experiment provided evidence for the assertion that: a. protein is the genetic material b. protein only enters the cell when it is not radioactively labeled c. viruses are only made of DNA d. DNA is the genetic material 33. DNA mutations that occur in somatic cells can lead to: a. cancer unless DNA repair mechanisms intervene b. genetic variation in off-spring c. no change in the resulting protein sequence d. a and c e. all of the above 34. Which of the following is not a function of RNA? a. carrying the genetic code from the nucleus to the cytoplasm b. providing a site for protein translation c. translating an individual codon into an amino acid d. storing the genetic code 35. Biomedical researchers use the program BLAST to: a. rapidly translate a genetic sequence b. identify a protein sequence using a database c. locate genes on the chromosome d. automatically interpret a DNA fingerprint 36. All protein sequences begin with which amino acid? a. b. c. d. methionine tyrosine proline isoleucine Figure 5 Mr. Body was killed in the library with the candlestick. There must have been a struggle since DNA from one of the suspects was found under Mr. Body’s nails at the scene of the crime. DNA fingerprinting was done using this crime scene DNA and the DNA of the four suspects, Ms. Scarlett, Mrs. Peacock, Mrs. White, and Professor Plum, resulting in the DNA fingerprint shown above. 37. Mr. Body was probably killed by which suspect? a. Ms. Scarlett b. Mrs. Peacock c. Mrs. White d. Professor Plum 38. DNA fingerprinting technology relies on the fact that: a. a typical human can be uniquely identified based on their genetic sequence b. DNA fragments separate on the basis of charge in an electrophoretic gel c. DNA restriction enzymes cut DNA at random positions d. a and c 39. Which type of mutation can result in a truncated protein product? a. chromosomal mutation b. point mutation c. frameshift mutation d. gamma mutation 40. Which type of mutation is referred to as silent when it does not result in a change in the protein product? a. chromosomal mutation b. point mutation c. frameshift mutation d. gamma mutation 41. Which of the following does not account for the low incidence rate of cancer? a. the double stranded nature of DNA which facilitates DNA repair b. the effectiveness of the immune system at eliminating cancerous cells c. the stability of DNA which does not mutate easily d. the presence of multiple copies of crucial genes 42. Which type of mutation is responsible for most of the genetic variation in the human population? a. chromosomal mutation b. point mutation c. frameshift mutation d. gamma mutation