Download C. African American

NAME _____________________________ f12
Chapter 14 -GENETIC DISORDERS TEST
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
A. ACHONDROPLASIA
B. HUNTINGTON’s
C. COLORBLINDNESS
D. TAY-SACHS
E. HEMOPHILIA
F. SICKLE CELL DISEASE
G. CYSTIC FIBROSIS
H. PHENYLKETONURIA
I. TURNER SYMDROME
J. DOWN SYNDROME
K.KLINEFELTER SYNDROME
L. DUCHENNE MUSCULAR
DYSTROPHY
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
and result in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation resulting in a person with a normal size
head and torso, but short arms and legs
NAME _____________________________ f12
Chapter 14 -GENETIC DISORDERS TEST
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
A. TAY-SACHS
B. ACHONDROPLASIA
C. HUNTINGTON’s
D. COLORBLINDNESS
E. HEMOPHILIA
F. CYSTIC FIBROSIS
G. DOWN SYNDROME
H.KLINEFELTER SYMDROME
I. TURNER SYNDROME
J. SICKLE CELL DISEASE
K. PHENYLKETONURIA
L. DUCHENNE MUSCULAR
DYSTROPHY
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
and result in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation resulting in a person with normal size
head and torso, but short arms and legs
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
NAME _____________________________ f12
Chapter 14 -GENETIC DISORDERS TEST
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
A.
B.
C.
D.
E.
F.
PHENYLKETONURIA
CYSTIC FIBROSIS
HUNTINGTON’s
COLORBLINDNESS
HEMOPHILIA
SICKLE CELL DISEASE
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
which results in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Defect in ion channels which transport Cl- ions causing mucous to build up
in lungs and digestive organs
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Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation resulting in a person with a
normal size head and torso, but short arms and legs
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
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A. TURNER SYNDROME
B. DOWN SYNDROME
C. TAY-SACHS
D.KLINEFELTER SYNDROME
E. ACHONDROPLASIA
F. DUCHENNE MUSCULAR
DYSTROPHY
MULTIPLE CHOICE:
Tell how each of the following disorders is inherited:
_______
Achondroplasia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Sickle Cell Disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Hemophilia
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Tay-Sachs disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Down syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Colorblindness
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Duchenne Muscular Dystrophy
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Phenylketonuria (PKU)
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Cystic Fibrosis
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Turner syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
_______
Klinefelter syndrome
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
________
Huntington’s disease
A. autosomal dominant
B. autosomal recessive
C. autosomal COdominant
D. X-linked recessive
E. nondisjunction
MULTIPLE CHOICE:
Put the letter of the answer that best completes the statement on the blank at the left.
_______ In humans an XX genotype makes you a ___________________
A. male
B. female
C. mutant
D. carrier
________
________
________
_________________ cell mutations happen in sperm or eggs and can be passed on to the
offspring.
A. Body
B. Somatic
C. Germ
D. Allele
____________________ mutations cause death, often before birth.
A. Somatic cell
B. X-linked
C. Germ cell
D. Lethal
__________________ cell mutations happen in body cells so they affect the organism itself,
but are NOT passed on to offspring.
A. Gamete
B. Somatic
C. Germ
D. Allele
_______ In humans an Xy genotype makes you a ____________________.
A. male
B. female
C. mutant
D. carrier
________
A gene that is carried on an X or Y chromosome is called ______________________.
A. sex influenced
B. sex linked
C. autosomal
D. lethal
________
The failure of homologous chromosomes to separate during meiosis is called ______________
A. nondisjunction
B. frameshift
C. crossing over
D. synapsis
________ A family record that shows how a trait is inherited
over several generations is called a _____________
A. karyotype
B. Punnett square
C. pedigree
D. periodic table
________ A person that has one copy of a recessive autosomal allele and does not express the trait but can
pass it on to his/her offspring is called a __________________.
A. mutant
B. carrier
C. hemophiliac
D. gene marker
________
_______________________ can be carriers for AUTOSOMAL RECESSIVE disorders.
A. Only males
B. Only females
C. Both males and females
________
_______________________ can be carriers for X-LINKED RECESSIVE disorders.
A. Only females
B. Only males
C. Both males and females
________
A human cell with 3 copies of a chromosome would have 47 chromosomes instead of 46.
This condition is called ____________________.
A. monosomy
B. disomy
C. tetrads
D. trisomy
________
_____________________________ twins have identical DNA.
A. monozygotic
B. dizygotic
C. fraternal
D. trisomic
________
This picture of an organism’s chromosomes is called a
______________________
A. pedigree
B. Punnett square
C. karyotype
________
The chromosomes that DO NOT determine sex are called ____________________
A. sex chromosomes
B. autosomes
C. gene markers
D. pedigree partners
________
Which parent determines the sex of the baby?
A. father
B. mother
________
The dense region in the nucleus of female cells that forms when one of the X chromosomes is
randomly inactivated is called a _____________________ body.
A. autosomal
B. sex-linked
C. nucleolus
D. Barr
________
Turner’s syndrome is an example of a _____________________ disorder.
A. trisomy
B. monosomy
C. somatic cell mutation
________
X-linked recessive disorders show up more frequently in ____________________.
A. females
B. males
________
Sickle cell disease is found more frequently in __________________________ populations.
A. Jewish
B. Caucasians
C. African American
________
Tay-Sachs disease is found more frequently in_________________________ populations.
A. male
B. Caucasion
C. African American
D. Jewish or Middle Eastern
________
Cystic fibrosis is found more frequently in _______________________ populations.
A. male
B. Caucasion
C. African American
D. Jewish or Middle Eastern
Match the symbol letter with the correct description (Circle ONE best answer)
Which member of this family shows the trait?
A
B
C
D
E
F
Which represents a male is a carrier for this trait?
A
B
C
D
E
F
A and E in the diagram above are __________________
A. normal females
B. normal males
C. diseased males
D. diseased females
B and D in the diagram above are __________________
A. normal males
B. carrier males
C. diseased females
D. carrier females
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BONUS
Which genetic disorder can be found in a pedigree showing the royal families of Europe?
A. Huntington’s disease
B. hemophilia
C. colorblindness
D. Achondroplasia
What trait changes in female cats as a result of the production of Barr bodies?
A. length of whiskers
B. length of tail
C. length of hair
D. spot color
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