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Mills Biology I 2014-2015 Name ___________________________________ DNA, RNA, Protein Synthesis and Mutations Test Review -KEYChapter 12 pages 329-349 TEKS 5C: Describe the roles of DNA, RNA and environmental factors in cell differentiation. 6B: Recognize that components that make up the genetic code are common to all organisms. 6C: Explain the purpose and process of transcription and translation using models of DNA and RNA. 6D: Recognize that gene expression is a regulated process. 6E: Identify and illustrate changes in DNA and evaluate the significance of these changes. Summary of Topics to Review Structures and functions of DNA and RNA Nucleotide structure and how they are arranged to form DNA and RNA Structure and functions of they types of RNA Processes of protein synthesis, including transcription of DNA and translation of mRNA Translate codons of mRNA using Genetic Code chart Identify how changes in DNA may cause mutations Distinguish between the types of mutations Mitosis and chromosome number in daughter cells Distinguish between photosynthesis and cell respiration and where each process occurs in cells Structures of leaves, including functions of xylem and phloem and stoma Sample Questions 1. The diagram below shows a process occurring in cells. Name the process and label items 1-5 on the diagram. 1. 2. 3. 4. 5. mRNA Ribosome Amino acid Protein/polypeptide tRNA 2. What is transcription and where does it occur in the cell? Making a mRNA copy of DNA; occurs in nucleus 3. What is translation and where does it occur in the cell? Using the mRNA message to make proteins; occurs at the ribosomes, which are found in the cytoplasm. 4. 3 nucleotides (nitrogen bases) = 1 codon = 1 amino acid 5. Given this DNA strand, find its (refer to Genetic Code chart on page 303): G T A C A T C T T A A C G C A T A T mRNA: C A U G U A G A AU U GCG U A U A amino acids: tRNA: His Val Glu Leu Arg Iso G U A C AU C U U A A C G CU U A U 6. Label the diagrams as either proteins, DNA or RNA. DNA mRNA Proteins or Peptide Chain 7. In the diagram below, circle a phosphate group, circle a 5-carbon sugar, and name all the nitrogen bases present. Is this molecule a DNA nucleotide or an RNA nucleotide? This is a DNA nucleic acid, with Adenine (A), Cytosine (C), Guanine (G) and Thymine (T) nitrogen bases present. Phosphate 5-Carbon Sugar or Deoxyribose 8. Genes made of DNA contain information for assembling _____. a. purines b. proteins c. pyrimidines d. nucleosomes 9. Name the 3 types of gene mutations. 1. Deletion 2. Insertion 3. Substitution 10. Are all mutations harmful? No 11. Can mutations lead to genetic variation? Yes 12. Name a genetic disorder caused by a gene mutation. Sickle Cell Anemia, Huntington’s Disease 13. Compare the following codon sequences: (6E) GUG-UGA-CGC-UGU-CCA And GUG-UGA-CCG-CUG-UCC-A Which mutation is being illustrated? a. deletion b. insertion c. substitution d. inversion 14. Which of the following shows a mutation that does not change the shape or the chemical nature of the protein so that it still functions normally? a. UGU to UGG b. GCA to GAG c. ACG to AGA d. CGA to CGG 15. Label the following on the diagram below: Mitochondrion, Chloroplast, Reactants for Photosynthesis, Products for Photosynthesis, Reactants for Cellular Respiration, and Products for Cellular Respiration Chloroplast Reactants of Photosynthesis and Products of Cell Respiration Products of Photosynthesis and Reactants of Cell Respiration Mitochondrion 16. Review the structures of leaves and view the Figure 23-18, p 596. List functions of the following: a. Guard cells form stoma; changes in their shape causes the opening and closing of stoma b. Stoma where gas like CO2 to enters plants and O2 leaves plants c. Phloem transports soluble organic molecules and nutrients made during photosynthesis d. Xylem transport tissue of plants, which carries water