recent trends in pharmaceutical chemistry for drug discovery
... a process referred to as combinatorial chemistry. In this technique, one part of a molecule is maintained, as different chemical groups are attached to its molecular framework to produce a series of similar molecules with distinct structural variations. Combinatorial libraries of these molecular var ...
... a process referred to as combinatorial chemistry. In this technique, one part of a molecule is maintained, as different chemical groups are attached to its molecular framework to produce a series of similar molecules with distinct structural variations. Combinatorial libraries of these molecular var ...
NS - Alyce Dickinson
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
CLASSICAL AND INSTRUMENTAL CONDITIONING: THE
... findings was obtained by Soltysik, who has shown that the "indirect" connections of Wyrwicka were mediated by the drive or emotional tenter - fear center in defensive reflexes and hunger center in alimentary reflexes (Fig. 4, right). My present concept concerning instrumental conditioning is basical ...
... findings was obtained by Soltysik, who has shown that the "indirect" connections of Wyrwicka were mediated by the drive or emotional tenter - fear center in defensive reflexes and hunger center in alimentary reflexes (Fig. 4, right). My present concept concerning instrumental conditioning is basical ...
neuropharmacological profile of somina (herbal drug) in mice and rats
... Pentothal induced sleeping time Rats were pretreated with Somina (285mg/kg) or Somina (10g/kg) or vehicle 30 min before Sodium Pentothal (42mg/kg) administration. The onset to loss the righting reflex was recorded and induction of sleep time. The onset to loss the righting reflex and the time betwee ...
... Pentothal induced sleeping time Rats were pretreated with Somina (285mg/kg) or Somina (10g/kg) or vehicle 30 min before Sodium Pentothal (42mg/kg) administration. The onset to loss the righting reflex was recorded and induction of sleep time. The onset to loss the righting reflex and the time betwee ...
Habituation, sensitization and Pavlovian conditioning
... stimulus as the CS. The more proximal nature of the US relative to the CS is true even for paradigms where the CS and the US are first encountered through the same sensory modality. For example, in taste preference conditioning, the gustatory stimulus is the CS, and the nutritive value of food which ...
... stimulus as the CS. The more proximal nature of the US relative to the CS is true even for paradigms where the CS and the US are first encountered through the same sensory modality. For example, in taste preference conditioning, the gustatory stimulus is the CS, and the nutritive value of food which ...
NS - Alyce Dickinson
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
NS - Alyce Dickinson
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
... US (light increase) --> UR (pupil of eye constricts) US (light decrease) --> UR (pupil of eye dilates) US (touch to eye/chemical irritant) --> UR (lachrimal gland secretion) US (irritation to nasal mucosa) --> UR (sneezing) US (irritation to throat) --> UR (cough) US (low temperature) --> UR (shiver ...
Lecture - Alyce Dickinson
... If Italians are always paired with “gangsters,” or “mafia,” if females are described as “inferior,” if Jews are described as “sly” and “shrewd,” if Arabs and Muslims are always described as “terrorists,” if gays are always described as “immoral,” etc., you can develop negative reactions to those gro ...
... If Italians are always paired with “gangsters,” or “mafia,” if females are described as “inferior,” if Jews are described as “sly” and “shrewd,” if Arabs and Muslims are always described as “terrorists,” if gays are always described as “immoral,” etc., you can develop negative reactions to those gro ...
NS - Alyce Dickinson
... B. X-rays X-rays are energy changes, but they cannot be stimuli for humans because humans do not have receptors that can detect them. (bats, sharks, etc. – radar/sonar -important to stress energy change that affects the receptors, cont) ...
... B. X-rays X-rays are energy changes, but they cannot be stimuli for humans because humans do not have receptors that can detect them. (bats, sharks, etc. – radar/sonar -important to stress energy change that affects the receptors, cont) ...
Psychology 381
... • S-R system activated by each stimulus that elicits a response – Each activation is stimulus specific – S-R activation and resultant habituation process universal features of elicited behaviour ...
... • S-R system activated by each stimulus that elicits a response – Each activation is stimulus specific – S-R activation and resultant habituation process universal features of elicited behaviour ...
Wise Up! Presentation for Parents
... • Average age people start drinking is 12.9 years • One out of 20 high school seniors drink daily ...
... • Average age people start drinking is 12.9 years • One out of 20 high school seniors drink daily ...
Punishment
... behavior when given noncontingently – That is, a targeted behavior neither produces nor prevents the punisher – when aversive stimuli occur independently of ...
... behavior when given noncontingently – That is, a targeted behavior neither produces nor prevents the punisher – when aversive stimuli occur independently of ...
Gobbi 2005 - Iowa Medical Marijuana
... actions: For example, even when administered at doses that completely inhibit brain FAAH activity, URB597 does not cause catalepsy, hypothermia, or hyperphagia, three key signs of cannabinoid intoxication in the rodent (16). Notably, however, URB597 elicits profound anxiolytic-like effects in rats, ...
... actions: For example, even when administered at doses that completely inhibit brain FAAH activity, URB597 does not cause catalepsy, hypothermia, or hyperphagia, three key signs of cannabinoid intoxication in the rodent (16). Notably, however, URB597 elicits profound anxiolytic-like effects in rats, ...
Punishment
... behavior when given noncontingently – That is, a targeted behavior neither produces nor prevents the punisher – when aversive stimuli occur independently of ...
... behavior when given noncontingently – That is, a targeted behavior neither produces nor prevents the punisher – when aversive stimuli occur independently of ...
Midterm 1
... A. We say that depolarization has occurred along the axon B. Neurotransmitters are released into synapses C. The activated cell can either excite or inhibit the adjacent cells based on the chemicals released *D. The refractory period varies based on the strength of the activation that occurred % Cor ...
... A. We say that depolarization has occurred along the axon B. Neurotransmitters are released into synapses C. The activated cell can either excite or inhibit the adjacent cells based on the chemicals released *D. The refractory period varies based on the strength of the activation that occurred % Cor ...
PPT - The Citadel
... or pairing of one significant reinforcing stimulus (like friendship and intimacy) with another less significant or neutral stimulus (e.g., initial use of alcohol, marijuana, ecstasy, cocaine). In learning to use drugs the following occurs: Conditioning: The close association of significant reinfor ...
... or pairing of one significant reinforcing stimulus (like friendship and intimacy) with another less significant or neutral stimulus (e.g., initial use of alcohol, marijuana, ecstasy, cocaine). In learning to use drugs the following occurs: Conditioning: The close association of significant reinfor ...
Introduction to Perception
... Figure 1.13 Results of a hypothetical experiment in which the threshold for seeing a light is measured by the method of constant stimuli. The threshold - the intensity at which the light is seen on half of its presentations - is 180 in this experiment. ...
... Figure 1.13 Results of a hypothetical experiment in which the threshold for seeing a light is measured by the method of constant stimuli. The threshold - the intensity at which the light is seen on half of its presentations - is 180 in this experiment. ...
28/03 - Instituto de Psicologia da USP
... presumably nicotine, may increase cortical membrane turnover or modify cell density. Together, these results add to growing evidence that nicotine exerts neurotoxic effects in human brain, although an a priori nature of the findings cannot be ruled out. ...
... presumably nicotine, may increase cortical membrane turnover or modify cell density. Together, these results add to growing evidence that nicotine exerts neurotoxic effects in human brain, although an a priori nature of the findings cannot be ruled out. ...
THE EMOTIOGENIC BRAIN STRUCTURES IN CONDITIONING
... AM. Hence, the activation of the structures of the emotiogenic control system of memory creates a spatial-temporal organization of brain structures that promotes the appearance of the effector conditioned response. Through what mechanisms does the emotiogenic control system act on memory? There are ...
... AM. Hence, the activation of the structures of the emotiogenic control system of memory creates a spatial-temporal organization of brain structures that promotes the appearance of the effector conditioned response. Through what mechanisms does the emotiogenic control system act on memory? There are ...
Affective Computing
... • Affective reactions need not depend on cognition • Affective reactions may become separated from content ...
... • Affective reactions need not depend on cognition • Affective reactions may become separated from content ...
Predictability Modulates Human Brain Response to Reward
... ical scan, subjects underwent two whole-brain f unctional runs of 150 scans each (echo-planar imaging, gradient recalled echo; repetition time, 2000 msec; echo time, 40 msec; flip angle, 90°; 64 ⫻ 64 matrix, 24 5 mm axial slices acquired parallel to anteroposterior commissural line) for measurement ...
... ical scan, subjects underwent two whole-brain f unctional runs of 150 scans each (echo-planar imaging, gradient recalled echo; repetition time, 2000 msec; echo time, 40 msec; flip angle, 90°; 64 ⫻ 64 matrix, 24 5 mm axial slices acquired parallel to anteroposterior commissural line) for measurement ...
Midterm Examination Stress and Coping – PSY 325 Siena Heights
... D. Carcinogens found in the garden and shrubbery 2. Per NIOSH recommendations, light physical labor is best performed in which temperature range? A. 60-62 degrees F B. 70-75 degrees F C. 66 – 72 degrees F D. They make no such recommendation. Professor Talbot is attempting to trick you. 3. The greate ...
... D. Carcinogens found in the garden and shrubbery 2. Per NIOSH recommendations, light physical labor is best performed in which temperature range? A. 60-62 degrees F B. 70-75 degrees F C. 66 – 72 degrees F D. They make no such recommendation. Professor Talbot is attempting to trick you. 3. The greate ...
Behavioral verification of associative learning in whisker
... respiration and eye movements (Misslin 2003). Differences in the level of freezing during CS presentations are used to infer alterations in the acquisition or expression of CS fear. Many reports suggest that fear conditioning is a direct function of the intensity of the UCS. For example, Morris and ...
... respiration and eye movements (Misslin 2003). Differences in the level of freezing during CS presentations are used to infer alterations in the acquisition or expression of CS fear. Many reports suggest that fear conditioning is a direct function of the intensity of the UCS. For example, Morris and ...
NIH Public Access
... Reinstatement to the CS cues—Later during the same test session on day 21, lever presses evoked in response to a CS presentation were then assessed. A single, noncontingent presentation of the CS was delivered at the 40th minute of the 90 minute test session. Thus the initial 40 minutes of the 90 mi ...
... Reinstatement to the CS cues—Later during the same test session on day 21, lever presses evoked in response to a CS presentation were then assessed. A single, noncontingent presentation of the CS was delivered at the 40th minute of the 90 minute test session. Thus the initial 40 minutes of the 90 mi ...
Conditioned place preference
Conditioned place preference (CPP) is a form of Pavlovian conditioning used to measure the motivational effects of objects or experiences. This paradigm can also be used to measure conditioned place aversion with an identical procedure involving aversive stimuli instead. Both procedures usually involve mice or rats as subjects. This procedure can be used to measure extinction and reinstatement of the conditioned stimulus. Certain drugs are used in this paradigm to measure their reinforcing properties. Two different methods are used to choose the compartments to be conditioned, and these are biased vs. unbiased. The biased method allows the animal to explore the apparatus, and the compartment they least prefer is the one that the drug is administered in and the one they most prefer is the one where the vehicle is injected. This method allows the animal to choose the compartment they get the drug and vehicle in. In comparison, the unbiased method does not allow the animal to choose what compartment they get the drug and vehicle in and instead the researcher chooses the compartments.Humans have also been shown to develop conditioned place preferences; for example, individuals taking therapeutic doses of amphetamine develop a CPP for where they consumed the drug.