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DNA Scientists Formative Assessment
DNA Scientists Formative Assessment

... 1. Stated the Chromosome Theory of Inheritance by observing how traits were passed to the offspring using grasshopper sperm. 2. Using mutated bread mold they stated that One-Gene codes for One-Enzyme. 3. Hypothesized, in 1952, that protein was the transforming agent in Griffith’s experiment. Used Su ...
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... Describe the different types of mutations and how they affect the amino acid sequence o ______________________________– involves a single nucleotide mutation ...
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... • Insulin used to be harvested from pigs, but some individuals did not tolerate it. • we are now able to use bacteria to produce human insulin in large quantities. • is tolerated much better by patients. ...
Bio 102 Practice Problems The Double Helix
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... variety of logical reasons. Which one of the following was NOT cited as a reason to doubt that DNA was the genetic material? A. DNA is made up of only four nucleotides and is too simple to encode complex traits. B. The experiments were done with bacteria, and bacteria may be too simple to have genes ...
Genetic Disorders
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... Tay-Sachs disease is a fatal genetic lipid storage disorder in which harmful quantities of a fatty substance called ganglioside GM2 build up in tissues and nerve cells in the brain. The condition is caused by insufficient activity of an enzyme called beta-hexosaminidase A that catalyzes the biodegra ...
The Avery and Hershey-Chase Experiments
The Avery and Hershey-Chase Experiments

... • Hershey and Chase provided further evidence that heredity material in bacteriophages was found in DNA, not in proteins. – Many did not accept Avery’s conclusions until 1952 when Alfred Hershey and Martha Chase conducted this experiment with bacteriophages (viruses that attack bacteria) ...
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... newborn (HDFN) or neonatal alloimmune thrombocytopenia (NAIT), and the mother need not be aggressively monitored or receive immune modulating agents. To determine the antigen status, fetal DNA can be isolated from cells obtained by amniocentesis or chorionic villus sampling. Alternatively, the disco ...
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Protein Synthesis Project

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... in the nucleotide sequence, or base pair sequence, of DNA. Most mutations are either neutral (they have no effect) or harmful, but occasionally mutations can actually cause a helpful change. Some mutations change only a single base in the DNA sequence – these are called point mutations. Other mutati ...
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Cell-free fetal DNA

Cell-free fetal DNA (cffDNA) is fetal DNA circulating freely in the maternal blood stream. It can be sampled by venipuncture on the mother. Analysis of cffDNA provides a method of non-invasive prenatal diagnosis.cffDNA originates from the trophoblasts making up the placenta. It is estimated that 2-6% of the DNA in the maternal blood is fetal in origin. The fetal DNA is fragmented and makes its way into the maternal bloodstream via shedding of the placental microparticles into the maternal bloodstream (figure 1). Studies have shown that cffDNA can first be observed as early as 7 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses. cffDNA diminishes quickly after the birth of the baby, so that it is no longer detectable in the maternal blood approximately 2 hours after birth. cffDNA is significantly smaller than the maternal DNA in the bloodstream, with fragments approximately 200bp in size. Many protocols to extract the fetal DNA from the maternal plasma use its size to distinguish it from the maternal DNA.Studies have looked at, and some even optimized, protocols for testing non-compatible RhD factors, sex determination for X-linked genetic disorders and testing for single gene disorders. Current studies are now looking at determining aneuploidies in the developing fetus. These protocols can be done earlier than the current prenatal testing methods, and have no risk of spontaneous abortion, unlike current prenatal testing methods. Non-invasive prenatal diagnosis (NIPD) has been implemented in the UK and parts of the US; it has clear benefits above the standard tests of chorionic villi sample (CVS) and amniocentesis which have procedure-related miscarriage risks of about 1 in 100 pregnancies and 1 in 200 pregnancies, respectively.As a method of prenatal diagnosis, cell-free fetal DNA techniques share the same ethical and practical issues, such as the possibility of prenatal sex discernment and sex selection.
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