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Genetic Engineering
Genetic Engineering

... • If you’re worried that the FDA approved something that it should not have, this is the best way to gather evidence of their mistake • If you think that the approved genetic modifications are safe, this is the best way to gather evidence to support that ...
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Phylogenetic DNA profiling : a tool for the investigation of poaching
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Too good to be true? DNA sequencing by Oxford Nanopore. Now.
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Ectopic Gene Expression in Mammalian Cells

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... different amino acid, the result may be a protein that cannot reach its final shape – Ex: Hbs which causes sickle-cell disease ...
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DNA, chromosomes and Genes

... Interestingly, the Human Genome Project reveled we all have mutations in our DNA sequence which do not affect the phenotype!! Occurs at a very low rate: about 1 in 1mil bases. UV radiation and some chemicals can increase the rate – These agents are linked to cancer - cancer arises when there is a ch ...
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BC2004
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Chapter 24: Genes and Chromosomes
Chapter 24: Genes and Chromosomes

... Describe a current hypothesis to explain the presence of functional DNA in mitochondria and chloroplasts. Ans: These organelles are thought to have originated from aerobic bacteria and photosynthetic bacteria, which took up endosymbiotic residence within primitive eukaryotic cells. The DNA molecules ...
Discussion Questions
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... Discussion Questions: “The Power of Three” 1. Turnbull was inspired by a child named Edward. What disease did Edward have? Describe this disease and its current treatment. 2. Why do mitochondria have their own DNA, and why do children inherit it only from the mother? 3. There are several oppositions ...
Genetics and Recombinant DNA
Genetics and Recombinant DNA

...  Extrachromosomal, circular small (2-3 kb) DNA in a bacterial cell which can replicate independently but which cannot integrate into the host chromosome.  Drug resistance plasmids are not essential for the cell's growth, but confer antibiotic resistance.  Plasmids used for molecular cloning ha ...
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Extrachromosomal DNA



Extrachromosomal DNA is any DNA that is found outside of the nucleus of a cell. It is also referred to as extranuclear DNA or cytoplasmic DNA. Most DNA in an individual genome is found in chromosomes but DNA found outside of the nucleus also serves important biological functions.In prokaryotes, nonviral extrachromosomal DNA is primarily found in plasmids whereas in eukaryotes extrachromosomal DNA is primarily found in organelles. Mitochondrial DNA is a main source of this extrachromosomal DNA in eukaryotes. Extrachromosomal DNA is often used in research of replication because it is easy to identify and isolate.Extrachromosomal DNA was found to be structurally different from nuclear DNA. Cytoplasmic DNA is less methylated than DNA found within the nucleus. It was also confirmed that the sequences of cytoplasmic DNA was different from nuclear DNA in the same organism, showing that cytoplasmic DNAs are not simply fragments of nuclear DNA.In addition to DNA found outside of the nucleus in cells, infection of viral genomes also provides an example of extrachromosomal DNA.
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