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Gene Section AF1q (ALL1 fused gene from chromosome 1q)
Gene Section AF1q (ALL1 fused gene from chromosome 1q)

... Tse W, Zhu W, Chen HS, Cohen A. A novel gene, AF1q, fused to MLL in t(1;11)(q21;q23), is specifically expressed in leukemic and immature hematopoietic cells. Blood 1995 Feb ...
Diffusion and random walks - California Institute of
Diffusion and random walks - California Institute of

... Figure 21–37 The regulatory hierarchy of egg- polarity, gap, segmentation, and homeotic selector genes. The photographs show expression patterns of representative examples of genes in each category, revealed by staining with antibodies against the protein products. The homeotic selector genes, discu ...
WilsonR Whit Abstract
WilsonR Whit Abstract

... Osteocytes, cells embedded within bone matrix, have been shown to regulate of bone adaptation, signaling bone formation or resorption based on mechanical cues from their microenvironments. However, studies thus far have only investigated the collective cellular behavior of osteocytes. Because bone i ...
Lec206
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... Trans-heterozygous phenotypes • When two genes are in the same “pathway” mutants heterozygous for both genes will display a phenotype even though each individual heterozygous mutant does not • Can be combined with ENU mutagenesis to screen for genes in the same pathway as another known “knocked out ...
VII. Some methods for studying gene expression
VII. Some methods for studying gene expression

Name Epigenetics http://learn.genetics.utah.edu/content/epigenetics
Name Epigenetics http://learn.genetics.utah.edu/content/epigenetics

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supplementary materials and methods

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Reverse Transcription PCR (RT-PCR)
Reverse Transcription PCR (RT-PCR)

... observing proteins • Can only determine transcription ...
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...  Proto-oncogenes can become oncogenes  Leads to an increase in protein production  OR an increase in the activity of normal protein ...
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... 1. Network-based identification of candidate cancer genes • Identification of functionally relevant genes in copy number regions • Co-expression and transcriptional analysis 2. Identification of differentially expressed miRNAs and their target genes in the GBM network 3. Identification of prognostic ...
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DNA Methylation
DNA Methylation

... • If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. • If the allele from the mother is imprinted, then only the allele from the father is expressed. • Forms of genomic imprinting have been demonstrated in fungi, plants and ...
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... decreased mobility and are genomic silencing regions, while the centre is dynamic and transcriptionally active. • Gene kissing is the intra (cis) or interchromosomal (trans) overlap of sequences within the same position, causing transcription activation or repression. • Transcription factories const ...
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... complex chain of reactors linked together by a mul3tude of control networks that normally determine its func3onality. Most disaster-like processes involve a sequence of events that occurs due to the availability of residual energy and materials. Understanding this p ...
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2 Sex chromosomes

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... BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2). Cancer Res. 2003 Sep 1;63(17):5329-34 Rohr O, Lecestre D, Chasserot-Golaz S, Marban C, Avram D, Aunis D, Leid M, Schaeffer E. Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodefic ...
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... Hemoglobin is a protein composed of two pairs of globin molecules. During the process of development from conception to adulthood, human hemoglobin changes in composition. Adult hemoglobin consists of two alpha- and two beta-globin molecules. Two globin genes occur on chromosome 16: alpha- and zeta- ...
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... In this example there three heterozygous possibilities AB, AO, and BO and one homozygous possibility OO ...
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Chapter 18: Regulation of Gene Expression
Chapter 18: Regulation of Gene Expression

... Different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns. Regulatory proteins specific to cell type control intron-exon choices by binding to regulatory sequences within the primary transcript. ...
Gene Expression Deconvolution with Single-cell Data
Gene Expression Deconvolution with Single-cell Data

... 2DEPARTMENT OF MOLECULAR AND CELL BIOLOGY ...
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Long non-coding RNA

Long non-coding RNAs (long ncRNAs, lncRNA) are non-protein coding transcripts longer than 200 nucleotides. This somewhat arbitrary limit distinguishes long ncRNAs from small regulatory RNAs such as microRNAs (miRNAs), short interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), and other short RNAs.
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