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the genome of herpes simplex virus: structure, replication and
the genome of herpes simplex virus: structure, replication and

... as enabling replication of covalently linked sequences, as head-to-tail concatemers, and was termed ‘on's’, for ‘short region origin of replication’ (Stow & McMonagle, 1983). M uch further work on the properties of oris has now been performed, and in addition a similar element (onL) has been detecte ...
MAGMA manual (version 1.03)
MAGMA manual (version 1.03)

... analysis. This can be used to obtain gene p-values combined across multiple data sets as well as to prepare input for gene-level analysis on the combined results of multiple data sets. To compute meta-analytic gene p-values the genes modifier is used, which is followed by a comma-separated list of t ...
B2_Key Recall Questions
B2_Key Recall Questions

... He suggested that ‘factors’ were inherited, scientists did not know about genes at the time so did not know what these ...
AP Biology Notes Outline Chapter 27 Bacteria and Archaea Concept
AP Biology Notes Outline Chapter 27 Bacteria and Archaea Concept

...  Many prokaryotes are decomposers, breaking down dead organic matter.  Many prokaryotes are symbiotic, forming crucial relationships with other species.  Some prokaryotes are pathogenic and cause illness by producing poisons. Antibiotics are chemicals that can kill prokaryotes. They are NOT effec ...
the attached document
the attached document

... He suggested that ‘factors’ were inherited, scientists did not know about genes at the time so did not know what these ...
Unusual mutations in high functioning fragile X males
Unusual mutations in high functioning fragile X males

... found in the 5' untranslated region of the FMR1 gene."A Large increases of repeat size are called full fragile X mutations and usually coincide with hypermethylation of the expanded repeat5 6 and of upstream promoter elements.' This results in downregulation of transcription8 and absence of FMR1 pro ...
Mapping strategies for sequence reads (with focus on RNA-seq)
Mapping strategies for sequence reads (with focus on RNA-seq)

... uires a set of known junctions from the reference ond, the QPALMA pipeline’s initial mapping phase ...
Gene quantification using real-time quantitative PCR
Gene quantification using real-time quantitative PCR

... DNA copy number measurements are important in determining the extent of genomic imbalance that underlies most malignancies. There are numerous techniques available for measuring DNA copy number in tumors; each method has specific advantages and disadvantages. Chromosomal CGH can detect imbalances ac ...
GenotoxiCity
GenotoxiCity

... The Ames test typically uses five strains of Salmonella with preexisting mutations that render the bacteria unable to synthesize the essential amino-acid histidine, and, as a result, cannot grow in histidine-free medium. If a compound induces mutations on these particular genes, it can restore gene ...
AGING Dr Aubrey de Grey Chief Science Officer
AGING Dr Aubrey de Grey Chief Science Officer

... Death from aging is not only “natural causes” ...
Clustering of mandibular organ-inhibiting hormone and moult
Clustering of mandibular organ-inhibiting hormone and moult

... clone (l12) were determined and are compared in Fig. 3. The results show that there are three exons and two introns in all MIH and MO-IH genes analysed ( Figs. 2 and 3). Exons 1 and 2 contain coding sequences for the signal peptide, and introns of 347 bp or 785 bp separate the two exons of the MIH a ...
Transcription
Transcription

... 2. Make up the catalytic center of the RNA polymerase 3. Their sequences are related to those of the largest subunits of eukaryotic RNA polymerases, suggesting that there are common features to the actions of all RNA polymerases. 4. The b subunit can be crosslinked to the template DNA, the product R ...
v5_02_alcoholism_and_our_genes
v5_02_alcoholism_and_our_genes

... one neuron that control the activity of another neuron. • Neurotransmitters bind to receptor molecules on the surface of responsive cells. • Variants in genes that influence neurotransmitter receptors influence susceptibility to alcoholism. • The receptors important in alcoholism control excitation ...
biofundamentals - virtual laboratories
biofundamentals - virtual laboratories

... non-random events. These evolutionary mechanisms (which we will discuss in some detail) include the origin of mutations, that is, changes that alter the genetic material (double-stranded deoxyribonucleic acid or DNA) and the effects of these molecular variation on the behavior of the organis(their p ...
neurotic, a novel maternal neurogenic gene, encodes an O
neurotic, a novel maternal neurogenic gene, encodes an O

... relatively recently identified as components of Notch signalling, such as Suppressor of Hairless, Kuzbanian, Presenilin and Nicastrin belong to this class of genes (Lecourtois and Schweisguth, 1995; Rooke et al., 1996; Struhl and Greenwald, 1999; Ye et al., 1999; Chung and Struhl, 2001; López-Schier ...
Oliver, B., Kim, Y.-J., and Baker, B. S.
Oliver, B., Kim, Y.-J., and Baker, B. S.

... determine the order of function of two genes is to inquire whether one gene regulates the expression of the other. To this end, our initial experiments address whether the sexspecific functioning of Sxl in the germ line is regulated by alternative pre-mRNA processing as it is in the soma. A finding ...
Lectures prepared by Christine L. Case Chapter 8 Microbial Genetics
Lectures prepared by Christine L. Case Chapter 8 Microbial Genetics

... Transformation in bacteria  Genes are transferred as “naked” DNA in solution.  It can occur between unrelated genus/species.  It was discovered by F. Griffith 1928 who studied ...
Updated slides on gene prediction
Updated slides on gene prediction

... • Allows for higher precision in identifying true ORFs; much better than merely testing for length. • However, average vertebrate exon length is 130 nucleotides, which is often too small to produce reliable peaks in the likelihood ratio • Further improvement: in-frame hexamer count (frequencies of p ...
Living Things - Santee School District
Living Things - Santee School District

... What is the relationship between chromosomes and genes? ...
the handout for this video.
the handout for this video.

... a. P1 is the only antigen 1) P, Pk not officially in P system anymore 2) These three antigens define the overall P phenotype. 3) Most common P phenotype: P1 (P+P1+Pk–). b. Very rare people lack all three and make anti-PP1Pk. 1) Acute HTR and early spontaneous abortions c. P antigen is parvovirus B19 ...
QSTAR - Institute of Bioinformatics
QSTAR - Institute of Bioinformatics

... Laplace FARMS for detection of sparse signals in gene expression data ...
Arabidopsis dth9 Mutation Identifies a Gene Involved
Arabidopsis dth9 Mutation Identifies a Gene Involved

... number in wild-type plants after 3 to 5 days of growth (cf. wt[L] and dth9[L] growth curves in Figure 3A). To study this susceptibility of dth9 plants to the virulent bacteria in more detail, we addressed whether or not the dth9 mutant could be compromised in the SAR response. We inoculated wild-typ ...
rs6445975 SNPedia tehranchi
rs6445975 SNPedia tehranchi

... rs6445975 is located on chromosome 3p14.3 and corresponds to intron 4 in the PXK gene (Phox homology domain containing serine/threonine kinase) and is associated with systemic lupus erythematosus (SLE). It is expressed in a variety of tissues including brain, heart, skeletal muscle, and peripheral b ...
Document
Document

... Response: was corrected to: development Whereas, there were no hairy roots formed from control explants. When cotyledon explants were also infected and co-cultured with Agrobacterium, no hairy roots induced on these explants. Response: the statement was changed to: , whereas no adventitious roots fo ...
Comparative analysis of the Geobacillus hemicellulose utilization locus reveals a highly
Comparative analysis of the Geobacillus hemicellulose utilization locus reveals a highly

... cluster which is not essential for hemicellulose degradation, encodes a transporter of L-arabinose monosaccharides (cluster A). A gene cluster with a role in the degradation and utilization of the pectin-associated polymer L-arabinan has also been described in G. stearothermophilus T-6 [21] and is p ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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